Neurotransmitters - facts Flashcards
(7 cards)
1
Q
Main neurtransmitters involve in generation of wake
A
Acetylcholine Dopamine Glutamate Histamine Hypocretin (orexin) Norepinephrine Serotonin
2
Q
Main neurotransmitters in generation of sleep
A
Acetylcholine (REM sleep) Adenosine GABA Galanin Glycine Melatonin
3
Q
Responsible for cortical EEG desynchroniation during wake and REM
A
Acetylcholine
4
Q
Anticholinergic drugs e.g. TCA
A
decrease REM
5
Q
Adenosine receptor blocker
A
Caffeine
6
Q
Dopamine agonsts
A
D1 increase wakefulness
e.g. amphetamines release dopamine
D2/D3 agonists e.g. pramipexole and ropinirole paradoxically cause sedation by presynaptc auto inhibiton of dopamine of dopamine
7
Q
Dopamine antagonist
A
promote sleep e.g. haldol, chlorpromazine
