Neurotransmitters Week 2

Question 1

How neurons communicate with eachother

Answer 1

Neurotransmission

Question 2

Action potential signals release of ___________

Answer 2

neurotransmitters

Question 3

Neurotransmitter result in _____ or ______ in post synaptic cell

Answer 3

EPSP or IPSP

Question 4

Synthesis of neurotransmitters in soma or terminal button

Answer 4

Step 1: of synaptic transmission

Question 5

Storage (stay in terminal button till needed)

Answer 5

Step 2: Synaptic transmisson

Question 6

Release (Action potential changes voltage and Ca+ floods the cell)

Answer 6

Step 3: Synaptic transmission

Question 7

Binding ( postsynaptic receptors -control receptors and autoreceptors)

Answer 7

Step 4: Synaptic transmission

Question 8

Deactivation (reuptake and degredation)

Answer 8

Step 5: Synaptic transmission

Question 9

Recycling

Answer 9

Step 6: Synaptic transmission

Question 10

receptor binds to ion channel

Answer 10

ionotropic

Question 11

uses energy; metabolic process

Answer 11

Metabotropic

Question 12

_______ units signal channel to open/slow process

Answer 12

G protein

Question 13

Most common mechanism of neurotransmitter deactivation

Answer 13

Reuptake

Question 14

Presynaptic neuron recaptures neurotransmitters (binds, does its job, floats around, gets reabsorbed)

Answer 14

Reuptake

Question 15

Enzymes break down neurotransmitters within the synapse (microglia clean up)

Answer 15

Enzymatic Degradation

Question 16

3 Chemical Messengers in the brain

Answer 16

Neurotransmitters
Neuromodulators
Neurohormones

Question 17

chemical messenger of the brain, acts on nearby cells

Answer 17

Neurotransmitters

Question 18

Diffuse to act on distant cells

Answer 18

Neuromodulators

Question 19

Endocrine system; cant travels great distances through circulatory system;

Answer 19

Neurohormones

Question 20

1. synthesis and storage
2. release
3. receptor binding
4. response mimicry
5. inactivation

Answer 20

Neurotransmitter Criteria

Question 21

3 Classifications of neurotransmitters:

Answer 21

• Small Molecule
• Neuropeptides
• Soluble Gas

Question 22

3 classifications of Small molecule neurotransmitters

Answer 22

• Amino Acids
• Monoamines (biogenic)
• Acetylcholine

Question 23

Types of Neuropeptides

Answer 23

• Endorphines
• Substance P
• Insulin
• Oxytocin

Question 24

Types of soluble gas

Answer 24

• Nitric Oxide

- Carbon Monoxide

Question 25

ACh is synthesized from:

Answer 25

- Acetly-CoA (muscle movement) - Choline - ChAT

Question 26

ACh is packed into vesicles by:

Answer 26

vesicular Ach transporter

Question 27

Receptors of ACh:

Answer 27

``` Nicotinic FAST(ionotropic) muscarinic (metabotropic) ```

Question 28

ACh is degraded by:

Answer 28

AChE

Question 29

ACh reuptake by:

Answer 29

choline transporter

Question 30

- Common synthetic pathway and structure - vesicular and reuptake transporters - degradative pathways

Answer 30

catacholamines

Question 31

receptors of catacholamines

Answer 31

metabotropic

Question 32

Amino Acids: Excitatory

Answer 32

Glutamate

Question 33

Amino Acids: Inhibitory

Answer 33

GABA | Glycine

Question 34

peptide secreted by neurons that functions as a signaling molecule

Answer 34

Neuropeptides

Question 35

diverse, often long-lived effects; substance P

Answer 35

neuropeptides

Question 36

exclusively in the hypothalamus; B-endorphin

Answer 36

Opiods; Endorphin

Question 37

Most abundant endogenous opiod peptides

Answer 37

Enkephalins and dynorphins

Question 38

Found in the periaqueductal gray and dorsal horn of spinal cord

Answer 38

Enkephalins and dynorphins

Question 39

Inhibit the flow of pain information to the brain

Answer 39

Enkephalins and dynorphins

Question 40

Mu, Kappa, Delta

Answer 40

Opiod receptors