neutrophils Flashcards

1
Q

what are the different functions of neutrophils

A

phagocytosis, degranulation and NETs

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2
Q

describe the neutrophil process of phagocytosis

A

pathogen releases chemical signals that attract neutrophils, neutrophils use PRRs to bind to and phagocytose

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3
Q

describe the neutrophil process of degranulation

A

this is the release of anti-bacterial proteins from neutrophil granules into extracellular fluid, killing extracellular pathogens(bacteria and fungi), could cause tissue damage and (possibly)systemic inflammation

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4
Q

describe the neutrophil process of NETs

A

NETs = Neutrophil Extracellular Traps
cell commits suicide in order to trap and kill pathogen, NETs are composed of the cells DNA, histones, enzymes and granular proteins

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5
Q

what type of cell are NK(natural killer) cells

A

lymphocytes

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6
Q

what cells do NK cells target and kill

A

specifically infected or abnormal(cancerous) cells

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7
Q

how do they kill other cells

A

they release cytotoxins that cause the cell to undergo apoptosis

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