pro-inflammatory mediators

Question 1

name some pro-inflammatory mediators

Answer 1

TNF alpha, histamine, C3a, C5a

Question 2

what is the function of pro-inflammatory mediators

Answer 2

they cause acute inflammation

Question 3

describe some of the physiological changes caused by acute inflammation

Answer 3

vasodilation of small vessels, increased permeability of PCVs, stimulation of nerve endings, swelling/pain

Question 4

describe the vascular changes caused by acute inflammation

Answer 4

vasodilation/increase blood flow, larger gaps in vessel wall, expression of adhesion molecules on endothelial cells(wall), recruitment and activation of neutrophils