Normal Ion concentrations Flashcards
(66 cards)
1
Q
Sodium extracellular
A
140mM
2
Q
Sodium intracellular
A
5-15mM
3
Q
Bicarbonate intracellular
A
10-20mM
4
Q
Bicarbonate extracellular
A
25mM
5
Q
Calcium intracellular
A
0.1 micromolar
6
Q
Calcium extracellular
A
2.4mM
7
Q
K+ extracellular
A
4mM
8
Q
K+ intracellular
A
140mm
9
Q
Hydrogen ions and pH extracellular
A
40mM, pH =7.4
10
Q
Hydrogen ions and pH intracellular
A
50-100mM, pH-7-7.3
11
Q
Plasma glucose in fasting
A
4mM-6mM
12
Q
Cl- Intracellular
A
25 mM
13
Q
Cl- Extracellular
A
110mM
14
Q
Plasma osmolarity
A
~300mOsm/L
15
Q
Resting membrane potential
A
-70mv
16
Q
Ek
A
-90mv
17
Q
ENa
A
+55-60mv
18
Q
ECl
A
-65-45mv
19
Q
Systemic blood pressure
A
120/80mmHg
20
Q
Pulmonary blood pressure
A
20/10mmHg
21
Q
PaO2
A
100mmHg, 13.3Kpa
22
Q
PaCO2
A
40mmHg, 5.3Kpa
23
Q
PvCO2
A
45mmHg
24
Q
What is the number of WBC in a litre
A
7 x 10^9
25
What is percentage of neutrophils
40-70%
26
What is the percentage of basophils
<1%
27
What is percentage of monocytes
6%
28
What is proportion of lymphocytes
20-40%
29
Diameter of RBC
7.2 micrometer
30
Normal V/Q ratio
0.8
31
What is normal heart rate at rest
60-100
32
What is alveolar ventilation rate
4L /min
33
What is resting SV
70ml
34
What is resting cardiac output
5L
35
What is basal O2 consumption
250ml/min
36
What is basal CO2 production
200ml/min
37
What is normal pulse pressure?
40mmHg
38
Normal CVP
5mmHg
39
Rough bp in arterioles and capillaries
Arterioles: 50mmHg
Capillaries: 20mmHg
40
Duration of normal neurone AP and in skeletal muscle
Neurone 1ms
Skeletal muscle 2-5ms
41
How do you work out clearance of something from blood
Urine conc x urine flow rate/ plasma conc
42
Range of urine osmolarity
30-1200mOsm
43
What are volumes of body fluid compartments
Total: 42
Intracellular: 28
Extracelular as plasma: 3, as interstitial fluid: 10, Transcellular fluid: 1
44
Cells of RBC in one litre
5 x 10^12
45
What is haematocrit
45%
46
What is GFR
125ml/min
47
How do you work out Volume of distribution (Vd)?
Dose/Concentration
48
How do you work out drug clearance (2 ways)?
(Dose/Interval)/ Total steady state plasma concentration
Elimination constant x Volume of distribution
49
What is percentage of eosinophils
3%
50
How to work of total peripheral resistance
(MAP-CVP)/ CO= TPR
51
How to find VO2/ rate of O2 uptake?
CO ( arterial O2 conc - venous O2 conc)
52
BP in foot capillaries can reach ...
100mmHg
53
Systolic pressure in right ventricle
25mmHg
54
What is the respiratory quotient?
CO2 eliminated/O2 consumed
It is a dimensionless number ratio used in a calculation for basal metabolic rate
55
How to calculate alveolar ventilation rate
(tidal volume - dead space) x breath rate
56
Anatomical dead space?
150ml
57
Tidal volume?
500ml
58
Inspiratory reserve volume?
Max air intake after normal inhalation ~ 3L
59
Expiratory reserve volume?
Max air exhalation after normal exhalation ~1.5L
60
Residual volume?
Volume left in lungs after maximum exhalation~1.2 L
61
Functional residual capacity?
ERV + RV ~2.5-3L
62
Vital capacity?
After max inhale the max exhale ~5L
63
Glomerular hydrostatic pressure
45mmHg
64
Renal plasma flow
625ml/min
65
Diuresis urine
Up to 20l/day / 20ml/min @ 50mosm
66
Antidiuresis urine
0.5l/day @ 1200mosm
