Nucleic Acids Flashcards

(42 cards)

1
Q

DNA

A

Deoxyribonucleic acid

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2
Q

What are the nitrogenous bases if DNA?

A

Adenine - Thymine
Guanine - Cytosine

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3
Q

Basic Nucleotide Structure

A

Phosphate, Pentose sugar, Nitrogenous Base

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4
Q

Purines

A

Two-ring structure. Adenine and Guanine.

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5
Q

Pyrimidines

A

Cytosine, Thymine and Uracil

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6
Q

RNA

A

Ribonucleic acid

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7
Q

What are the nitrogenous bases in RNA?

A

Adenine - Uracil
Guanine- Cytosine

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8
Q

Structure of DNA

A

Double helix structure

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9
Q

Structure of RNA

A

Single stranded

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10
Q

Function of DNA

A

Repository of genetic information

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11
Q

Function of RNA

A

Involved in protein synthesis and gene regulation; carrier of genetic information in some viruses

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12
Q

What are the monomers of nucleic acids?

A

Nucleotides.

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13
Q

What are the three components of a nucleotide?

A

Phosphate group, pentose sugar, nitrogenous base.

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14
Q

What are the four bases in DNA?

A

Adenine, thymine, cytosine, guanine.

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15
Q

Which base replaces thymine in RNA?

A

Uracil.

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16
Q

What is the sugar in DNA and RNA?

A

Deoxyribose in DNA, ribose in RNA.

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17
Q

What type of bond forms between nucleotides?

A

Phosphodiester bond.

18
Q

What is complementary base pairing in DNA?

A

A pairs with T, C pairs with G via hydrogen bonds.

19
Q

Describe the structure of DNA.

A

Double helix formed by two antiparallel strands joined by complementary base pairing.

20
Q

What is semi-conservative replication?

A

Each new DNA molecule has one old strand and one new strand.

21
Q

Which enzymes are involved in DNA replication?

A

DNA helicase (unwinds) and DNA polymerase (adds new nucleotides).

22
Q

What are the roles of mRNA, tRNA, and rRNA?

A

mRNA carries code, tRNA brings amino acids, rRNA forms ribosomes.

23
Q

What is the process of transcription?

A

Copying a gene into mRNA using RNA polymerase.

24
Q

What is the process of translation?

A

mRNA is decoded by ribosome to assemble a polypeptide chain.

25
What is ATP and what is it made of?
Adenosine triphosphate; adenine, ribose, and three phosphate groups.
26
How does ATP release energy?
By hydrolysis of the terminal phosphate bond to form ADP + Pi.
27
What enzyme is involved in ATP synthesis?
ATP synthase.
28
What is transcription?
The process of copying a gene's DNA sequence into a complementary mRNA strand.
29
Where does transcription occur?
In the nucleus of eukaryotic cells.
30
What enzyme is used in transcription?
RNA polymerase.
31
What happens during the initiation stage of transcription?
RNA polymerase binds to the promoter region of the DNA.
32
What is the role of RNA polymerase?
It unwinds DNA and synthesizes mRNA using complementary base pairing.
33
What is the product of transcription?
A single-stranded mRNA molecule.
34
What is translation?
The process of decoding mRNA to build a polypeptide (protein).
35
Where does translation occur?
In the cytoplasm at the ribosome.
36
What molecules are involved in translation?
mRNA, tRNA, ribosomes, and amino acids.
37
What does tRNA do in translation?
tRNA carries specific amino acids and has anticodons that pair with mRNA codons.
38
What is a codon?
A sequence of three mRNA bases that codes for one amino acid.
39
What is an anticodon?
A three-base sequence on tRNA that is complementary to a codon on mRNA.
40
What happens during the elongation phase of translation?
Amino acids are joined together by peptide bonds to form a polypeptide chain.
41
What is the role of ribosomes in translation?
They facilitate the binding of tRNA to mRNA and catalyse peptide bond formation.
42
What signals the end of translation?
A stop codon is reached on the mRNA.