Nuerons Flashcards
(40 cards)
what is the cell membrane?
the semipermeable membrane surrounding the cytoplasm of a cell.
(double layer)
what is polarization of a cell?
difference in electrical charge between the inside and outside of a cell
what is voltage?
the difference in electrical charge between two points
what is resting potential?
A resting (non-signaling) neuron has a voltage across its membrane
what does resting potential charge come from?
ions
what are ions?
any atom or group of atoms that bears one or more positive or negative electrical charges.
- Positively charged ions are called cations; negatively charged ions, anions.
what is negatively charged?
chloride, proteins & amino acids
what is positively charged?
Na+ and K + (sodium and potassium)
why does resting potential occur?
because of the unequal distribution of +/- ions across membrane
what happens to Na+ and K+ during resting potential?
at rest, Na+ is outside the cell and K+ is inside, when nueron fires an abrupt reversal of electrical charge occurs (Na+ and K+ switch)
what is action potential?
A large, sudden and brief reversal in the polarity of a membrane. (an abrupt depolarization (becomes less negative) inside the cell membrane)
why does action potential occur?
when different ions cross the neuron membrane. A stimulus first causes sodium channels to open (Na+). Because there are many more sodium ions on the outside, and the inside of the neuron is negative relative to the outside, sodium ions rush into the neuron.
what are postsynaptic potentials?
a temporary change in the electric polarization of the membrane of a nerve cell (neuron).
what happens during postsynaptic potentials?
chemical transmission of a nerve impulse at the synapse, the postsynaptic potential can lead to the firing of a new impulse.
what do postsynaptic potentials look like?
they are graded (waves)
what are excitatory postsynaptic potentials?
small local depolarization (inside becomes more positive)
what are inhibitory postsynaptic potentials?
small local hyperpolarization (inside becomes more negative)
where do postsynaptic potentials take place?
axon hillock
what is the threshold of excitation?
a level above which any simulation produces a massive depolarization
what is a synapse?
The junction between the most distal (farthest from soma) part of an axon terminal and the membrane of a second neuron.
what are the postsynaptic receptors?
The particular effect of a neurotransmitter on the postsynaptic membrane depends on these
(ionotropic and metatropic)
what is a ionotropic receptor?
open channels directly produce fast action
- opens directly and rapidly when the
correct neurotransmitter molecule binds with it.
what is a metabotropic receptor?
open channels indirectly and slowly to produce longer lasting effects
- This type of receptor opens more slowly, and has longer lasting and more diffuse effects.
what are glial cells?
Cells in the CNS that can become malignant.