Nutrition Lecture Flashcards

(51 cards)

1
Q

Macronutrients?

A

Carbs/Sugars
Amino acids
Fatty acids and lipids

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2
Q

Micronutrients?

A

Vitamins
Minerals
Water

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3
Q

Adequate diet?

A

Energy (carbs, fats, proteins)
Essential/Nonessential amino acids and fatty acids (building blocks for synthesis of structural and functional proteins and lipids)
Vitamins and minerals (coenzymes and hormones in metabolic pathways - calcium and phosphate)

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4
Q

Dietary Essentials?

A

Not produced by the body
Provided by diet
- Phenylalanine, leucine, isoleucine, methionine, valine, tryptophan, threonine, lysine

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5
Q

Dietary nonessentials?

A

Synthesized by body

- Glycine, serine, aspartic acid

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6
Q

Nutrient deficiencies?

A

Developing: Common undernutrition or protein-energy malnutrition
Industrialized: dietary impropriety can cause: atherosclerosis, cancer, diabetes, hypertension

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7
Q

Primary malnutrition?

A

One or all of the components are missing

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8
Q

Secondary or conditional malnutrition?

A

Supply of nutrients is adequate

Malnutrition occurs: nutrient malabsorption, impaired nutrient use of storage, excess nutrient losses, increased need

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9
Q

Reasons for deficiencies?

A
Poverty
Infections
Acute and chronic illnesses
Ignorance and failure of diet supps
Chronic alcoholism (thiamine, pyridoxine, folate, vit A)
Self imposed: anorexia, bulimia
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10
Q

Nutritional Disorders

A

Protein-energy malnutrition
Anorexia or Bulimia
Vitamin Deficiencies
Mineral Deficiencies

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11
Q

Protein-Energy Malnutrition

A

Low body weight, fat storage and reduced plasma proteins
Determined by BMI
Children- loss of skeletal muscles and subq fat
25% in developing
High death rate among children >5 yo

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12
Q

Marasmus

A

Somatic protein compartment
- Severe reduction in caloric intake
60% reduction in weight

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13
Q

Kwashiorkor

A
Visceral protein compartment
Protein deprivation
African kids: weaned too early bc of another kid, receive exclusively carb diet
Muscle and fat are not effected
Causes fatty liver
- Hypoalbuminemia + generalized edema
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14
Q

Consequences of Marasmus

A
Loss of muscle 
Growth retardation
Subq fat used as fuel
Head appears too large
Anemia, multivitamin deficiences
Immune deficiency
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15
Q

Related disease to kwashiorkor

A
Nephrotic syndrome
Damaged kidneys
After extensive burns
Enteropathies after protein loss
Non absorption of proteins because of chronic diarrhea
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16
Q

Anorexia

A

Self induced starvation
Similar to PEM consequences
Permanent effects of system
Amenorrhea: decreased secretion of gonadotropin-releasing hormone, luteinizing hormone, and follicle-stimulating hormone
Cold intolerance, bradycardia, constipation, change in skin and hair, decreased bone density, postmenopausal

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17
Q

Bulemia

A

Individual binges and pukes
Amenorrhea (less than 50%)
Medical complications: electrolyte imbalance (cardiac arrhythmias), pulmonary aspiration of gastric content, esophagel and cardiac rupture

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18
Q

Vitamin deficiencies

A

4 fat soluble
- more readily stored, poorly absorbed in GI of fat malabsorption
9 water soluble

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19
Q

Fat soluble

A

A
D
E
K

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20
Q

A

A

visual pigment and cell proliferation

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21
Q

D

A

Facilitates intestinal Ca and K absorption and bone mineralization
- synthesized endogenously

22
Q

E

A

Antioxidant and radical scavenger

23
Q

K

A

Cofactor in hepatic carboxylation of pro-coagulants –> bleeding disorders
- synthesized endogenously

24
Q

Water soluble

A
B1
B2
Niacin
B6
B12
C
Folic Acid
Pantothenic acid
Biotin
25
B1
Thiamine | Pyrophosphate
26
B2
Riboflavin | Flavin nucleotides
27
Niacin
Incorporate into nicotinamide adenine nucleotides (redox rxn) - synthesized endogenously
28
B6
Pyridoxine | Derivatives serve as coenzymes in rxns
29
B12
Required for folate metabolism and DNA synthesis
30
C
Serves in many redox rxns and hydroxylation of collagen
31
Folic acid
Essential cofactor for nucleic acid synthesis
32
Pantothenic acid
CoA
33
Biotin
Carboxylation rxns | - synthesized endogenously
34
Zinc deficiency
Oxidases - rash around eyes, mouth, nose, and anus - anorexia and diarrhea - growth retardation
35
Iron deficiency
Hemoglobin | - anemia
36
Iodine deficiency
Thryoid hormone | - goiter and hypothyroidism
37
Copper deficiency
CytochromE C oxidase - Muscle weakness Neurologic defects
38
Fluoride deficiency
Dental caries
39
Selenium deficiency
Glutathione peroxidase and antioxidant | - Cardiomyopathy
40
Obesity
Sedentary lifestyle, socioexconomic conditions, availability of processed, high calorie foods, soft drinks - BMI, skin fold measurement, body circumference (hip to waste) - Increased morbidity and mortality - Prevention and management
41
BMI
703* (weight/ht^2) 25 normal 25-29.9 overweight 30+ obese
42
Central/visceral obesity
Accumulates fat in trunk and abs | - Higher risk of several diseases
43
Obesity etiology and definition
Genetic, environmental, psychological - Disorder of energy balance; when food-derived energy exceeds energy expenditure, the excess calories are stored as TGs in fat tissue - - Intake vs expenditure
44
Energy expenditure
Basal energy expenditure Thermic effect of food Activity related expenditure
45
Basal energy expenditure
Energy for metabolic processes while at rest | - 69% of total
46
Thermic effect of food
Energy required for digestion and absorption of food | - 10% of total
47
Activity related expenditure
Varies with level of activity | - 20-30% of total
48
Hungry
Ghrelin goes up and activates anabolic circuit --> want to eat -- increases leptin, insulin, and PYY, and reduces energy usage - Ghrelin falls, inhibition
49
Hyperinsulinemia
Decreased IGFBP-1/2 Increased bioavailability of IGF-1 --> Increases free IGF-1 for increased cell proliferation and decreased apoptosis (increased risk of cancer)
50
Less obese, less
Adiponectin | - Sensitivity to insulin --> more secretion --> hyperinsulinemia
51
Total food intake (calories)
1000-2000 day Carbs 50-60% Fat 30% Proteins 10-20%