O&G Sexual Health Flashcards

(57 cards)

1
Q

Risk factors for endometrial cancer

A

Age <35:
- chronic anovulatory bleeding
- diabetes
- FHx colon ca
- infertility
- nulliparity
- obesity
- tamoxifen use
- obese adolescents with 2-3 years untreated anovulatory bleeding
- >35 with anovulatory bleeding
- Bleeding not responsive to medical therapy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Causes of anovulatory bleeding

Irregular/infrequent periods
Range of flow from absent to excessive

A

Endometrial ca
PCOS
Diabetes
Hyper/hypothyroid
Hyperprolactinaemia
Antiepileptics, antipsychotics
Eating disorder
Adolescence, perimenopause, pregnancy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Causes of ovulatory bleeding

Regular bleeding intervals
Excessive or prolonged (>7 days) bleeding

A

Coagulopathy (von Willebrand’s, factor deficiency, leukaemia, platelet disorder)
Endometrial ca
Hypothyroid
Endometrial polyps
Uterine fibroids
Advanced liver disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Causes of first trimester bleeding

A

Miscarriage (10-20%)
Ectopic pregnancy (1-2%)
Cervical/vagina lesions (malignancy, ectropion, polyps)
Infection
Gestational trophoblastic disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Management of endometriosis

A

Tranexamic acid for menorrhagia
Hormone therapy
- Provera/depo-provera
- COCP
Paracetamol, NSAIDs (ibuprofen, naproxen, mefenamic acid)
Smoking cessation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Ectopic pregnancy:

Prevalence
Time of diagnosis
Location

A

1% pregnancies
6-10 weeks gestation
Fallopian tubes 95%
- Others in peritoneum, abdominal organs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Risks of ectopic pregnancy

A

Previous tubal surgery/pathology
Previous ectopic surgery
In utero diethylstilbesterol exposure
Prev STI/PID
Infertility
Current smoker
Current/prev IUD use

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Woman with pelvic pain - conditions to rule out

A

Ectopic pregnancy
Ruptured ovarian cyst
Ovarian torsion
PID
Appendicitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Management of abnormal anovulatory and ovulatory bleeding

A

Anovulatory
- COCP
- Provera

Ovulatory
- Mirena
- Provera
- TXA
- NSAIDs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Women with first trimester bleeding and haemodynamic instability

A

Ruptured ectopic pregnancy
Incomplete miscarriage with cervical shock (parasympathetic stimulation - hypotension, bradycardia)
Massive haemorrhage secondary to miscarriage

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Complications of endometriosis

A

Reduced fertility
Adhesions > bowel obstruction
Risk of ovarian ca - clear cell serous endometriod
Ovarian cysts - rupture and torsion
Inflammatory bowel disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Locations of endometriosis

A

Superficial peritoneal lesions <5mm deep
Deep infiltrating >5mm deep, or into muscular proper of organs
Ovarian endometrioma
Pleural, diaphragm, umbilicus lesions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

bHCG levels in normal vs ectopic pregnancies

A

Lower level in ectopic vs intrauterine pregnancy
Normal - increases 50-66% in 48 hours
Discriminatory level = 1500-3500 - level when pregnancy visible in uterus on ultrasound

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Prevalence of first trimester bleeding

A

20-40%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Types of miscarriage and management

A

RHD negative - refer to ED for Rh D immunoglobulins

Threatened - vaginal bleeding <20/40
- expectant management

Inevitable - miscarriage occurring/expected to occur
- expectant/medical/surgical

Incomplete - Some retention of POC
- expectant/medical/surgical

Missed - non-viable IUP, no bleeding
- expectant/medical/surgical

Complete - full passage POC

Septic
- Referral stat

Recurrent - >3 consecutive miscarriages

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Risks of placenta previa

A

Chronic HTN
Multiparity
Multiple gestations
Older age
Prev C section
Smoking uterine curettage

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Types of placenta previa

A

Complete previa - placenta overlies internal os
Marginal previa - placental edge within 2cm of os
Low-lying placenta - edge within 2-3.5cm os

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Presentation of placenta previa bleed vs plancental abruption

A

Gestation >20 weeks
Sudden onset painless PV bleeding, often after sex.

Abruption - with pain (uterine, back), bleeding may be concealed. Foetal distress, contractions, DIC

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Risks for placental abruption

A

Chronic HTN
Multiparity
Prev abruption
Pre-eclampsia
Short umbilical cord
Sudden decompression of extended uterus
Thrombophilia
Smoking
Drugs - cocaine, meth
Trauma
Fibroids
Raised maternal alpha fetoprotein

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Risks for vasa previa (umbilical cord inserting in lower uterine segment, foetal vessels between cervix and presenting part)

A

IVF
Low lying placenta/second trimester placenta previa
Marginal cord insertion
Multiple gestation
Succenturiate-lobed, bilobed placentae

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Blood volume of full term foetus

A

250mL

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Post partum haemorrhage - levels of shock

A

Mild shock
- <20% blood loss
- diaphoresis, cool peripheries, anxiety, delayed cap refill

Moderate shock
- 20-40% blood loss
- tachycardia, tachypnoea, postural drop, oliguria

Severe shock
- >40% blood loss
- Hypotension
- Agitation
- Altered mental state, LOC

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Causes of post partum haemorrhage

A

Uterine atony - oxytocin 10 IU + bimanual uterine massage
Trauma, vaginal/perineal laceration
Uterine inversion

24
Q

Prevalence of nausea and vomiting in pregnancy

Usual duration

A

60-70% mild nausea and vomiting
- Begins week 4-7, peaks week 9, resolves weeks 16-20

1-2% hyperemesis gravidarum

25
Management of hyperemesis gravidarum
Small frequent fluids and food (high carb low fat), avoid hunger Lie down if dizzy Avoid smells and triggers Acupressure Mild - No dehydration - PO antiemetic - oral rehydration Moderate - Dehydration (dizziness, dry MM, slow cap refill, postural drop, sunken eyes, slow skin turgor, tachycardia, hypotension) - Ketones >+2 - Community IVF and antiemetics Severe - >5% weight loss, biochemical abnormalities - Community +/- hospital IVF and antiemetic - Dietician referral - Thiamine + omeprazole Antiemetics of choice - cyclizine, metoclopramide, prochlorperazine, promethanzine, ondansetron
26
Risk factors for hyperemesis gravidarum
Molar pregnancy Multiple pregnancy Primiparous Young Non-smoker Chronic H. pylori Pasifika
27
Pre-eclampsia symptoms
>20 weeks gestation New onset hypertension Mild - 140-159 systolic, 90-109 diastolic Severe >160 systolic, >110 diastolic Plus one of: - Proteinuria +/- oedema - Organ dysfunction - Neuro (hyperreflexia, clonus, visual scotoma) - Haem (low platelets, haemolytic) - Renal impairment - Deranged LFTs - Uteroplacental dysfunction (growth restriction, abruption) HELLP - pre-eclampsia variant Haemolysis Elevated LFTs Low platelets
28
Eclampsia definition Timing
Seizure in pregnant patient with or without pre-eclampsia 60-90s duration, self-limiting 53% antepartum 19% intrapartum 28% 48 hrs postpartum Late post-partum = >2 weeks
29
Risk factors for pre-eclampsia
Major: - Antiphospholipid abs - SLE - Hx pre-eclampsia - self, mother, sister - Pre-existing HTN - Diabetes, renal disease Minor: - Oocyte donation - African, Indian, Maori, Pacific - Primiparous, pregnancy interval >10 years - Multiple pregnancies - Hx pre-eclampsia in paternal family - Change in partner, sperm donor - BMI >35 - Age >40
30
Management of pre-eclampsia
Urgent obstetrics referral Antihypertensives - labetalol, nifedipine, hydralazine Target BP 130-150/80-100 MgSO4 Aspirin and calcium to women at high risk of pre-eclampsia
31
Levonorgestrel for emergency contraception Indications Dose Contraindications
Levonorgestrel 1.5mg stat 3mg stat BMI >26 or >70kg Within 72 hours of UPSI (ideally 12hrs) Contraindications: clots, breast ca, IBD, porphyria, active trophoblastic disease Reduced efficacy within 28 days liver enzyme inducing meds - barbiturates, anti epileptics, rifampicin
32
Copper IUD for emergency contraception Indication Timing Side effects
BMI >26 more effective Only option for BMI >30 Insert within 5 days of ovulation or within 120 hours of UPSI May worsening heavy menstrual bleed or menorrhagia
33
STI testing for males
1. Urethral swab 2. First void urine - no PU within 1 hour, do not clean first, take first 30mL 3. Consider MSU for cystitis 4. Consider herpes swab Send for chlamydia + gonorrhoea NAAT
34
PID risk factors
<30 years Sexually active Recent change in sexual partner Multiple sexual partners Prev STI Post partum Post TOP Post instrumentation
35
Complications of PID
Tubo-ovarian abscess Chronic pain Ectopic pregnancy Tubal factor infertility Fitz-Hugh-Curtis syndrome - peri hepatitis
36
Management of PID
Usually ascending chlamydia, gonorrhoea infection Ceftriaxone 500mg IM with 2mL lignocaine 1% Doxycycline 100mg BD 14 days Metronidazole 400mg BD 14 days Leave IUD in, don't remove until on abx for >24 hours Contact trace and treat for chlamydia all partners of last 3/12 No sex until pain resolves Condoms for 14 days after treatment and 7 days after treatment of sexual contacts Repeat STI check in 3/12
37
Herpes subtypes
HSV 1 - mostly facial lesions. 30-40% genital herpes HSV 2 - 60-70% genital herpes 20% adults have asymptomatic HSV 2
38
Herpes symptoms First vs reactivation
Flu-like illness Painful ulcers, vesicular rash in groin, perineum, genitals, mucosa - lasts 2-3 weeks if untreated Tender local lymphadenopathy Dysuria and difficulty passing urine in women Reactivation: Smaller lesions, more closely grouped Lasts 5-10 days No flu-like prodrome
39
Herpes transmission and causes of reactivation
Skin to skin transmission Viral shedding 100-1000 times greater in active episode Unlikely fomites - virus dies at room temperature Lifelong infection - latent in ganglia of sensory nerves Reactivation and recurrence - Minor trauma - Other infection - UV radiation - Menstrual - Emotional stress
40
Management of herpes
Valaciclovir 500mg BD 7 days Immunocompromised: 1g BD 7-10 days Salt wash Lignocaine Increase fluids, urinate in shower Avoid sex Refer if herpes proctitis, neonates, pregnant Recurrence: Valaciclovir 500mg BD 3 days Prophylaxis for frequent recurrence: Valaciclovir 500mg OD or Acyclovir 400mg BD No increased risk of ca Not indicative of partner cheating
41
Genital warts presentation
90% caused by HPV 6, 11 Can appear 3-6 months after skin-skin contact Flesh coloured papule, may join together to form plaques Pain Bleeding Itch
42
Treatment for genital warts
Podophyllotoxin 5mg/mL apply BD for 3 consecutive days/week for 5 weeks Imiquimod 3 alternate days/week for 16 weeks Cryotherapy - only option in pregnancy Laser Hyfrecation Surgical excision Refer: - Children if NAI concerns, cervical warts, intraurethral, extensive, pregnancy, immunosuppression, diabetes, HIV, ?malignancy
43
Symptoms of primary syphilis
50% asymptomatic 10-90 days incubation Solitary genital/anal/mouth ulcer, usually painless - 30% multiple lesions - Resolves spontaneously
44
Transmission of syphilis
Treponema pallidum Contact with mucocutaneous skin Vertical transmission - congenital syphilis
45
Risks for syphilis
Sexually active Contact of syphilis case MSM Routine checks - sexual health - pregnancy - immigration
46
Signs of secondary syphilis
Incubation time 2-24 weeks 90% involving skin: - rash on palms or soles - generalised body rash - Atypical mouth ulcer - condylomata lata - patchy alopecia Constitutional: Fever, lethargy, lymphadenopathy Neuro: ocular nerve palsy, unilateral deafness, meningitis
47
Signs of tertiary syphilis
Atypical neuro - paraesthesia, ataxia, dementia, deafness, visual impairment Cardiovascular disease - aortitis Gummata - inflammatory nodules on skin/bone
48
Management of syphilis
Contact tracing Referral to sexual health - do not start treatment without advice (usually benazathine penicillin) Abstain from sex until treatment complete Notify MOH
49
Risks for gonorrhoea
<30 years sexual contact of gonorrhoea Recent gonorrhoea Multiple sexual contacts MSM Coexisting STI - HIV, chlamydia Inconsistent condom use Anal, oral sex Drug use Commercial sex work
50
Gonorrhoea symptoms
Symptomatic in 95% men and 50% women Purulent discharge, dysuria, abdo pain Men: scrotal pain, anal pain/pruritis/bleeding Women: abnormal bleeding, dyspareunia, rectal infections often asymptomatic 90% pharyngeal infections asymptomatic
51
Management of gonorrhoea
Ceftriaxone 500mg IM Azithromycin 1g stat If rectal chlamydia - add doxycycline 100mg BD 7 days Abstain or condoms for 1 week after treatment and treatment of contacts Contact trace 2 months Notify MOH Follow up 7 days
52
Most common STI in NZ Most common preventable cause of infertility
Chlamydia
53
Risk factors for chlamydia
Age <25 Sexual contact with chlamydia 2+ sexual partners in last year Recent change in sexual partner Inconsistent condom Co-infection with another STI
54
Symptoms of chlamydia
Asymptomatic in 50% men, 70% women Men: urethritis (dysuria, discharge), epididymo-orchitis (unilateral testicular pain, swelling) Women: Dysuria, vaginal discharge, intermenstrual/post coital bleeding, deep dyspareunia, lower abdo pain, fever Cervix - friable, "cobblestone" appearance, contact bleed Rectal chlamydia - asymptomatic in 70% MSM, 90% women. Proctitis + mucopurulent discharge
55
Treatment of chlamydia
1st line: doxycycline 100mg BD 7 days (97% effective) - More effective in rectal chlamydia 2nd line: azithromycin 1g stat (94% effective) - Emerging resistance in other STIs Abstain or condoms for 7 days post treatment of self and contacts Contact trace 2 months Follow up in 7 days
56
Routine STI check females
Vulvovaginal swab for chlamydia, gonorrhoea, +/- trichomoniasis (Maori, Pacific, low SES, incarceration, contact) HIV and syphilis serology Consider: Speculum + bimanual if symptomatic High vaginal swab - BV, candida Endocervical swab for gonorrhoea Anorectal, pharyngeal swabs Hep B, C serology
57
Routine STI check male
First pass urine for chlamydia, gonorrhoea HIV, syphilis serology Consider: Urethral swab for gonorrhoea if discharge Pharyngeal/anorectal NAAT swabs if MSM Herpes swab if ulceration Hep B, C serology Hep A serology if MSM