Obligate Intracellular Pathogens Flashcards
(40 cards)
True or False:
Rickettsiales family can only grow and reproduce inside a host cell
true
what type of organism is the rickettsiales family
gram negative
coccoid, rod-like
what is the best virulence factor of the Rickettsiales family
high strain variation through the ability to change surface protein expression
True or False:
It is easy for pathogens of the Rickettsiales family to evade the immune systems
true
what is used to treat pathogens of the Rickettsiales family
antibiotics (tetracyclines and chloramphenicol)
what cell types are the Rickettsiales family able to infect
immune cells or hemopoitic cells
what is the transmission route of the Rickettsiales family
ticks
fleas
flukes
what are the virulence factors of the Rickettsiales family
release of endotoxins
invade lots of cells
block phagolysosomal fusion or escape
which pathogen is responsible for rocky mountain spotted fever
R. rickettsii
which pathogen is responsible for canine monocytotropic ehrilichiosis
E. canis
which pathogen is responsible for canine granulocytic ehrilchiosis
E. ewingii
what is the target host of E. canis
dog
what is the target host of E. ewingii
Dog
human
what is the target host of E. chaffensis
Multiple + humans
what is the target host cell of E. canis
monocytes
macrophages
lymphocytes
what is the host cell target of E. ewingii
Neutrophils
what is the host cell target of E. ruminantium
vascular endothelial cells
neutrophils
what is the reservoir host of E. canis
multiple
what is the reservoir host of E. ewingii
white tailed deer
what is the reservoir host of E. ruminantium
wild and domestic rumiants
which ehrlichia spp is not found in the US
E. ruminantium
what disease does E. canis cause
canine monocytotropic ehrlichiosis (CME)
what disease is associated with E.. ruminantium
heartwater
what disease is associated with E. ewingii
canine granulocytic ehrlichiosis (CGE)
