Obs and Gynae Flashcards
(179 cards)
what causes stress incontinence?
weakened urethral sphincter muscles mean that the detrusor pressure > urethral closing pressure which causes leakage when coughing and exervising
RF for stress incontinence
menopause, vaginal births, congenital weakness, pelvic surgery
How do you investigate urinary incontinence?
Urine stix - exclude UTI freq/vol chart - functional capacity of the bladder urodynamics QoL questionaire vaginal exam
how do you manage stress incontinence?
- Conservative - 3 months of pelvic floor exercises, lose weight, stop smoking, treat a cough and constipation
- peri-urethral bulking agents
Medication: Duloxetine
what causes overactive bladder?
overactive detrusor muscle
what are the RF for an overactive bladder?
MS/neurological/incontinence surgery/increasing age
what provokes symptoms of an overactive bladder?
provoked by cold weather, opening the front door, coughing and sneezing
how do you manage an overactive bladder? what are the side effects of the first line medical treatment
- Lifestyle - avoid excess fluids, caffeine, carbonated drinks, alcohol
1st line = oxybutynin (anti muscarinic) - relaxes the detrusor by blocking the parasym - SE = dry mouth/constipation/nausea
2nd line = mirabegron (B3 agonist)
3rd line = botox injection
what is a prolapse?
protrusion of organs into the vagina due to weaened pelvic floor
Features of a prolapse (retrocele/cystocele)?
dragging sensation
Cystocele - urinary frequency/urgency/incomplete emptying
Retrocele - constipation/difficulty defacating
what are the RF for a vaginal prolapse?
prolonged labour, trauma and surgery to the pelvic floor, forcep delivery, chronic cough, obesity, high BMI
How do you investigate a prolapse?
clench test
bimanual examination
How do you manage a prolapse?
- pelvic floor exercises, lose weight, treat cough, stop smoking
- pessary (SE - discharge)
- surgical repair
what does LH do?
binds to theca cells which stimulates production of androgens
induces ovulation
what does FSH do?
binds to granulosa cells and converts androgens to oestrogen, and stimulates the production of inhibin
what are primary and secondary amenorrhea?
primary - no period by the age of 16
secondary - periods stop for >6 months in women with a previous regular cycle
Name some causes for primary amenorrhea?
congenital malformation of organs
Turner’s syndrome
familial
androgen insensitivity
what is Turner’s syndrome? what are the signs?
45X Coarction of aorta spade shaped chest - wide nipples and neck horseshoe kidney primary amenorrhea
what is androgen insensitivity syndrome?
peripheral insensitivity to testosterone despite having genotype 46XY - female phenotype but genetically male
name some causes of secondary ameonrrhea?
thyrotoxicosis PCOS Asherman's syndrome Sheeshan's syndrome prolactinoma hypothalamic
what is asherman’s syndrome?
scarred uterus from D&C - blood can’t leave uterus due to the scarring
what is sheeshan’s syndrome?
ischaemic damage to AP (panhypopituitarism)
name some causes of raised prolactin? what are the signs?
prolactinoma, antipsychotics (2nd generation)
galactorrhea, reduced libido, amenorrhea
how do you investigate amenorrhea?
bHCG, oestrogen, progesterone
FSH and LH levels
testosterone