Obstetrics Flashcards

(58 cards)

1
Q

What is a miscarriage?

A

The spontaneous termination of pregnancy; early is before < 12 weeks and late is 12 to 24 weeks

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2
Q

Different classifications of miscarriage?

A

Missed - no symptoms but the foetus is dead
Threatened - vaginal bleeding, cervix closed and foetus alive
Inevitable - vaginal bleeding with an open cervix
Incomplete - retained products of conception
Complete - full miscarriage
Aembryonic - no embryo, just gestational sac

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3
Q

Investigation for miscarriage

A

TVUS
1) Foetal HR?
2) Crown-rump length of 7mm?
3) Gestational sac of 25 mm diameter and foetal pole

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4
Q

Management of miscarriage

A

Less than 6 weeks - expectant
More than 6 weeks - expectant, medical (misoprostol) or SMM

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5
Q

Types of SMM

A

Manual vacuum aspiration - LA, syringe to aspirate, must be below 10 weeks. Better in parous women

Electric vacuum aspiration - GA

Rhesus D proph to rhesus negative women

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6
Q

Incomplete miscarriage management

A

Medical - misoprostol
Surgical - ERPC (evacuation of retained products of conception)

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7
Q

When to be concerned about miscarriages?

A

Infection or heavy bleeding

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8
Q

Define recurrent miscarriages

A

3 x first trimester
1 x second trimester

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9
Q

Causes of recurrent miscarriages

A

Idiopathic
Haematological (APLS and inherited thrombophilias)
Structural (fibroid, cervical insufficiency, congenital)
Genetics - balanced translocations
Chronic diseases - DM, thyroid, SLE
Other - chronic histiocytic intervillositis

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10
Q

Management of recurrent miscarriages

A

Referral to specialist

Pelvic US
Blood tests - APLS and hereditary thrombophilia
Genetics - of conception products and parents

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11
Q

Presentation of ectopic

A

Abdo/pelvic pain
Missed period
Bleeding
Cervical excitation
Dizziness and shoulder tip pain

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12
Q

Investigation for ectopic

A

TVUS - bagel sign

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13
Q

Management of ectopic pregnancy

A

Expectant - if unruptured, less than 35 mm, hCG < 1500, no HB or significant pain

Medical with methotrexate - same as above but hCG less than 5000

Surgical - laparoscopic salpingectomy or salpingotomy, with rhesus D proph is rhesus negative

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14
Q

Timeline of sickness in pregnancy

A

Starts at 4-7 weeks, peaks at 10 to 12 weeks and settles at 16-20 weeks

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15
Q

Definition of hyperemesis gravidarum

A

Protracted N&V plus 5% loss of body weight, dehydration an electrolyte imbalance

Can use PUQE score to quantify

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16
Q

Management

A

Obs, ketones, can they keep stuff down, weight

Cyclizine, prochlorperazine or metoclopramide, in that order

Think about reflux as an issue

Ginger and acupuncture

Depending on severity admission may be indicated for IV fluids, electrolyte correction, observation, IV antiemetics, thiamine and VTE proph

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17
Q

What is a hydatidiform mole?

A

A molar pregnancy is a tumour that grows like a pregnancy in the uterus

Two types: a complete and partial mole

Complete - no foetal material; two sperm fertalise and empy egg

Partial - some foetal material; two sperms fertilise an eg

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18
Q

Presentation of a molar pregnancy

A

Increased N&V
Vaginal bleeding
Abnormally large uterus
Abnormally high hCG
Thyrotoxicosis - hCG mimics TSH

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19
Q

Investigation for molar pregnancy

A

TVUS - snowstorm appearance

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20
Q

Management of molar pregnancy

A

Refer to gestational trophoblastic disease centre

Evacuation and follow-up

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21
Q

Anaemia in pregnancy

A

Screen at booking and 28 weeks, 110 and 105 respectively

Micro - give iron
Macro - give folate/B12

Remember pregnancy is a high volume, low pressure physiology and so there will be a dilutional anaemia to some degree

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22
Q

Pre-existing diabetes in pregnancy

A

5 mg of folate
Diet, metformin and insulin only
Opthalmology review shortly after booking and at 28 weeks
Planned delivery between 37 and 38+6
Sliding scale during labour if type 1

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23
Q

Gestational diabetes RFs

A

Had it previously, big baby, BMI over 30, ethnic origin and family hx of diabetes

They get OGTT at 24- 28 weeks, previous gestational diabetes also get one soon after booking

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24
Q

OGTT results and actions

A

Fasted, then give 75g of glucose
Fast - 5.6 upper limit
After 2 hours - 7.8 upper limit

fasted < 7 - a 1-2 week trial of exercise and diet
fasted >7 - inulin +/- metformin
if > 6 but big baby then start treatment anyway

Targets of 5.3 fasted, 7.8 an hours after meal and 6.4 two hours after

25
Why is diabetes bad?
Babies: - big - neonatal hypoglycaemia - jaundice - CHD - cardiomyopathy Mum: - delivers bigger baby
26
If already has HTN, which meds?
- labetalol - nifedipine - methyldopa - aspirin from 12 wekks
27
Management of gestation hypertension (> 20 weeks)
- treat for 135/85 - admit if 160/110 - dipstick weekly - weekly blood tests - serial growth scans - PlGF at least once - aspirin from 12 weeks if 1 x HRF or 2 x MRF
28
Management of pre-eclampsia
Largely the same as gestation HTN except for weekly dipsticks not needed as a diagnosis was made, BP every 48 hours and two weekly scans
29
Management of pre-eclampsia
Labetalol, nifedipine or methyldopa, with aspirin if needed
30
Management of eclampsia
Magnesium sulphate
31
Other considerations of pre-eclampsia
Planned delivery and corticosteroids?
32
High RFs for pre-eclampsia
- pre-existing HTN - previous NTH in pregnancy - autoimmune disorders - diabetes - CKD
33
Moderate RFs for pre-eclampsia
- age of 40 - BMI over 30 - 10 years since last pregnancy - multiple pregnancy - first pregnancy - FHx of pre-eclmapisa
34
Presentation of pre-eclampsia
- N&V - headache - visual disturbances - abdominal pain - oedema - reduced urine output - brisk reflexes
35
Diagnosis pre-eclampsia
HTN plus organ dysfunction either on dipstick, blood tests or placental scans
36
Complications of pre-eclampsia
HELPP (haemolysis, elevated liver enzymes and low platelets)
37
UTI in pregnancy
Pregnant women are routinely tested for UTI and symptomatic bacteremia - nitrofurantoin (not in the third trimester) - amoxicillin (need sensitivities) - cefalexin Can lead to premature birth
38
Medication for women with epilepsy
Lamotrigine and levetiracetam preferred, 5mg of folate
39
Depression in pregnancy
Common, can still take medications but a discussion about risks vs benefits needs to be had
40
Issues with obesity in pregnancy
Mum: - thrombosis - gestational diabetes - HTN and pre-eclampsia - increase likelihood of IoL, C-section, anaesthetic complications and wound infections Baby: - big baby - NTD - miscarriage and stillbirth 5mg dose of folic acid
41
VZV in pregnancy
- More severe in pregnant women leading to pneumonitis, hepatitis, encephalitis - Foetal varicella syndrome in unborn or severe infection if around delivery - If previous chickenpox then woman safe - Any doubt then IgG should be tested - If unprotected, then IV varicella IGs should be given within 10 days of exposure - If rash has developed, then give oral aciclovir if less than 24 hours and more than 20 weeks
42
What is congenital varicella syndrome?
If infected in the first 28 weeks, can cause: - growth restriction - microcephaly, hydrocephalus and LD - scars and skin changes across dermatomes - limb hypoplasia - cataracts and chorioretinitis
43
Syphilis during pregnancy
- prem - stillbirth/miscarriage - small baby - issues with placenta and cord
44
TORCH?
- Toxoplasmosis Tiad of intracranial calcification, hydrocephalus and chorioretinitis - Others - syphilis and hep B - Rubella MMR during conception/after birth, live vaccine so not during pregnancy. Can cause deafness, cataracts, CHD and LD - CMV FGR, microcephaly, vision loss, hearing loss, LD, seizures - HSV (HIV and Zika sometime included)
45
Define labour
process of uterine contractions and cervical dilation that enables the uterus to deliver a viable foetus (24 weeks), placenta and membranes. Diagnosed when there are regular and increasing painful uterine contraction brining about cervical dilation and/or effacement
46
What is the first stage of labour?
Onset of regular and increasing painful contractions to full dilation of the cervix Latent is fully effaced and 3cm dilated (6-8 hours first time and 4-6 hours after that) and active is to fully dilated (0.5cm/hr)
47
Stage 2 of labour
From full dilation to delivery of foetus (hur first time, half an hour after that)
48
Stage 3 of labour
From delivery of the foetus to delivery of placenta and membranes (15 mins or less with active management)
49
Causes of slow labour?
Power, passenger or passage
50
Active management of third stage
Syntometrine and controlled traction of cord
51
Three key steps to a successful labour
Reassurance, hydration and analgesia
52
Slow labour management
Oxytocin at 2- 4MU/min, then can increase by 2-4 MU if needed Aiming for 4-5 contractions every 10 minutes lasting at least 40 seconds Usually achieved at the 8-12 MU mark Beware of hyperstimulation, uterine rupture and water intoxication (ADH effect)
53
Process of labour
Enters occipito-trasnverse Head flexion Internal rotation Extension Restitution (external rotation) Anterior shoulder then posterior shoulder
54
Presentation of cord prolapse
Compression of the cord leads to foetal hypoxia, showing as foetal distress on the CTG Can be palpated and seen on PV and speculum exam
55
Management of cord prolapse
- put the mother in the left lateral position or knee-chest position - keep cord wet and warm (saline and gauze) with minimal handling - push presenting part of the head back - organise emergency caesarian - tocolytic agents
56
Biggest RF for cord prolapse
Abnormal lie
57
Presentation of shoulder dystocia
- struggle to deliver head - failure of restitution - turtle-neck sign
58