Obstetrics Flashcards
(154 cards)
Does MAP decrease or increase in pregnancy?
Descrease
Does preload decrease or increase in pregnancy?
Increase
Does heart rate decrease or increase in pregnancy?
increase
Does systemic vascular resistance decrease or increase in pregnancy?
Decrease
Does hemoglobin decrease or increase in pregnancy?
Decrease (RBC increase but plasma increases more)
Does FEV1 decrease or increase in pregnancy?
Doesn’t change
Does PaO2 decrease or increase in pregnancy?
Doesn’t change
Does the functional residual capacity decrease or increase in pregnancy?
Decrease
Does the tidal volume decrease or increase in pregnancy?
Increases
Changes in coagulation during pregnancy
↑von Willebrand factor= more fibrinogen
↑factors 7, 8, 10
↑inhibitor to tPA
↓Protein C, S and antithrombin
Nephrologic changes during pregnancy
o ↑GFR
o ↑Creatinine (0.4–0.8)
o More risk of kidney stones (usually at the pelvic brim)
GI changes durign pregnancy
o Reflux: PPI
o Nausea: Ondansetron
o Constipation: stool softener and motility agents
o Iron deficiency: Iron with stool softener and motility agents
o Gallbladder disease
What to do during the preconception visit
Safety: - Genetics - Age - Screen for domestic violence and abuse Vitamins: Folate Vaccines: - Flu IM - Hep B - MMRV (live attenuated) Lifestyle: - Smoking - Alcohol - Drugs/medications - Getting enough sleep - Manage stress - Plan maternity leave - Safe to have sex Optimization of disease - DM - HTN - Hypothyroid
First-trimester visit assessment.
Person
- Is the pregnancy desired? (abortion, adoption)
- Barriers to care
- Vitals
- Weight
- Screen for abuse and safety
- Social, medical, surgical, family histories
- Medications and allergies
First trimester visiti assessment tests/labs
- UPT
- Confirm with TV U/S (location of pregnancy, gestational age, multiple gestation)
- Hgb/hct
- ABO type
- Rh status
- HIV
- Hep B
- RPR
- Titers for varicella and rubella
- U/A + Urinary culture (infection and bBaseline of proteinuria)
- Screen for gonorrhea and chlamydia
- Cytology
- Genetic screen (cystic fibrosis for caucasic and sickle cell disease for african Americans)
Existing nomenclature to establish obstetric history
- GPAC (gravid, para, abortions, c-sections)
* (G)TPAL (gravid, term, pre-term, abortion, living)
Examples of aneuploidies
Trisomy
• Down’s: 21
• Edwards: 18
• Patau’s: 13
1st trimester screening for aneuploidy
- Nuchal translucency in a U/S (normal < 3 mm)
- PAPP-A
- hCG
2nd trimester screening for aneuploidy results for Down’s
↑ hCG
↓ PAPP-A
↓ Estriol
↑ Inhibin A
2nd trimester screening for aneuploidy results for Edward’s
↓ hCG
↓ AFP
↓ Estriol
↓ Inhibin A
Combined vs sequential screening for aneuploidy
Combined screening
- 1st trimester + 2nd trimester
- ↑Sensitivity
- It’s good when mom is negative, but if positive, she’ll have less options because you waited
Sequential screening
- 1st trimester –> invasive test if positive
- ↑Specific but more invasive
Risk factors of gestational diabetes
BMI > 30
Hx of gestational DM
Pre-diabetic
Dx of gestational diabetes
1-hr glucose tolerance test (50 gr)
• Positive if > 140
• If positive, do the 3-hr
3-hr glucose tolerance test (100 gr) Dx is made with 2 or more of these positive o Fasting > 95 o 1 hr > 180 o 2hr > 155 o 3 hr > 140
Tx of gestational diabetes
Insulin
- Goal: postprandial < 180