Oculomotor Mechanisms Flashcards

(45 cards)

1
Q

What type of lesions do eye exams reveal?

A

Central lesions.

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2
Q

Pick 2 conditions that are not a symptom of occulomotor disturbance:

  • Diploplia
  • Oscillopsia
  • Aphasia
  • Vertigo
  • Dysequilibrium
  • Brainstem related syptoms
  • Blindness
A

Aphasia, blindness

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3
Q

How many postural control adjustments are generated each day by the oculomotor complex?

A

100,000

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4
Q

What level of the brainstem is the occulomotor nucleus and nerve?

A

Rostral midbrain

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5
Q

Name the muscles not innervated by CNIII and name their nerve and function.

A

TROCHLEAR
Superior oblique
-down and out

ABDUCENS
Lateral rectus
-abduction

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6
Q

With a lesion to CNIII, what is the resting position of the eye?

A
  • Exotropia (outward)
  • Ptosis (eyelid drop)
  • Diploplia
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7
Q

What functional deficits exist with a CNIII lesion?

A

NO

  • upward gaze
  • medial gaze on side of lesion
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8
Q

What does the pupillary light reflex test?

A

Integrity between retina and midbrain (CNII, CNIII):
-retina>CNII (optic nerve) >midbrain>CNIII (sphincter)>direct consensual response

-important test of increased intracranial pressure

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9
Q

When describing the pupillary light reflex, what is direct and consensual response?

A

DIRECT
-the pupil in which the light is entering constricts

CONSENSUAL
-the pupil which is not receiving light constricts somewhat

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10
Q

What is the direct response circuit?

A

Retina (sensory) to optic nerve to optic tract to pretetum to CN III (motor).

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11
Q

The consensual response to light includes a crossing effect where?

A

The pretectum.

-cross to opposite side CN III which effect a response.

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12
Q

What happens to the pupillary light reflex with a CNIII lesion?

A

No constriction on side of lesion, but still consensual response.

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13
Q

What happens to the pupillary light reflex with a CN II (Marcus Gunn) lesion and how would you determine what side the lesion is?

A

No direct or consensual with light in the side of the lesion. When light is in non-lesion side, there will be direct and consensual.

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14
Q

Where is the nucleus of CN IV (trochlear)? What movement do you lose with a lesion?

A

CAUDAL MIDBRAIN

No downward gaze when adducted

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15
Q

Where is the nucleus of CN VI and what movement do you lose with a lesion? Does the resting position change?

A

CADUAL PONS

Esotropia (medial strabismus) & diploplia

No lateral gaze side of lesion

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16
Q

What level of the brain stem hosts horizontal conjugate gaze? What nucleus drives the gaze?

A

Pons.

Abducens nucleus handles all traffic.

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17
Q

Describe the recruitment pathway for horizontal conjugate gaze.

A

Lateral rectus neuron > abducens nucleus > interneuron > MLF (on opposite side) > CN III nucleus > medial rectus

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18
Q

If you had a lesion to CNVI nucleus on the right side, how does that affect conjugate horizontal gaze?

A

You would lose lateral rectus (CNVI) on the right and medial rectus (CNIII) on the left.

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19
Q

What is the function of the medial longitudinal fasiculus, and where is it located?

A

interconnects CN VI with contralateral CN III as well as vestibular nuclei.

Located medial to abducens nucleus.

20
Q

What happens with a lesion just to the MLF (internuclear opthalmoplegia)?

A

No ipsilateral adduction of the right eye with gaze to the left (contralateral).

21
Q

Where and what are the center s for vertical conjugate gaze? What nerves produce it?

A

Reticular formation in the midbrain.

CNIII innervating superior rectus bilaterally.

22
Q

Do eye movements involves lower motor neurons?

A

Yes, of III, IV and VI.

23
Q

What types of eye movements exist to hold the image on the fovea?

A
  • Gaze fixation
  • Vestibulo-ocular reflex (VOR)
  • Optokinetic nystagmus
24
Q

What is gaze fixation?

A

Ability to hold eye in fixed position.

25
Where is gaze fixation moderated in brain? What does it contain?
Rostral medulla Contains medial vestibular nucleus -reticular formation in midbrain
26
Where are the neural integrators for horizontal and vertical eye movement?
HOR -medial vestibular nucleus and nucleus prepositus hypoglossi in medulla VER -Interstitial nucleus of Cajal in midbrain
27
What does the VOR do?
Maintains a visual target with movement of the head. | -shortest latency in body (10ms)
28
Optokinetic nystagmus is a series of stablizing movements which include saccades and smooth pursuit. Describe each.
SACCADE - watching telephone polls; action that gets eye to next poll - voluntary or reflexive - very fast (250-600* / sec) SMOOTH PURSUIT -watch moving object Cortical initiation
29
How do you test saccades?
18 inch separation of fingers, have pt go back and forth.
30
What are the 2 steps of saccades?
Pulse -get eye to new position Step command to hold
31
What area of the frontal eye field initiates voluntary horizontal saccades? Where is it generated?
8 (cortical area). Generated in contralateral paramedian pointine reticular formation (PPRF) of pons. -burst signal to ipsilateral abducens nucleus, MLF.
32
What happens with damage to the front field?
Inability to initiate saccades to the contralateral side.
33
With damage to the frontal field, which direction is gaze preference?
Towards side of cortical lesion
34
With damage to pons, you cannot generate saccades to ipsilateral side. Which direction is gaze preference?
Away from side of lesion.
35
How much damage is required for vertical saccades to be affected?
Bilateral damage.
36
What is the alternative pathway to voluntary saccades (happens with horizontal lesion)?
Basal ganglia to superior colliculus.
37
Involuntary saccades do not require the cortex. What is their pathway?
Subcortical projection to superior colliculus. | -orienting behaviour.
38
Smooth pursuit requires cerebral cortex which projects to the ____ and ____ system.
Cerebellum and vestibular system.
39
When are corrective saccades seen?
Abnormal smooth pursuit.
40
T/F Mammals and converge for near focus and diverge.
False.
41
Why is it tiring to read in the dark?
Pupillary constriction occurs during convergence (required in reading) as a reflex. When it's dark you must dilate, which is working against the reflex.
42
How do you name a nystagmus?
In the direction of the fast (saccadic) component.
43
Name the 4 physiologic (normal) nystagmus.
1. Optokinetic (voluntary eye movement) 2. Rotation-induced - occur when you've been passively spun - first phase in same direction as spin 3. Caloric-induced - artificially inducing flow of endolymph in semi-circ canals - COOL = OPPOSITE - WARM = SAME 4. End-range nystagmus - seen at extreme end ROM
44
Name 4 pathological nystagmus.
1. Spontaneous - seen at rest - always CNS pathology 2. Gaze-evoked 3. Congenital (most are gaze-evoked) 4. Positional - change in head position (vertigo)
45
Do central nystagmus signs diminish over time?
No, only peripheral.