OM and lower resp infections Flashcards

1
Q

etiology of AOM

A

usually viral- rhino, paraflu, flu, entero

may lead to bacterial superinfection: strep pneumo, H flu, M catarrhalis. pneumococcal vaccine helps.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

When do you treat OM

A

if child under 2. if child is over 2 but has otorrhea or bilateral AOM. If over and severe disease (fever over 39).
if you decide to watch and wait and kid isn’t better within 72 hrs.
give antibiotics

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

complications of OM

A

eustachian tube dyfunction/recurrent infections
TM rupture
cholesteatoma
acute mastoiditis (brain infection, deep necak abcess, lateral sinus thrombosis)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Olser’s triad

A

endocarditis, meningitis, S. pneumo pneumonia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

presentation of acute bronchitis

A

persistent cough for 1-3 weeks, often w/ sputum production
fever and constitutional symptoms are uncommon
wheezing might be present.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

etiology of acute bronchitis

A

usually flu, paraflu, RSV (others like rjhino, corona, adeno possile)
atypical bacteria also can cause acute bronchits: mycoplasma, chlamydia, pertussis
typical bacteria DON’T cause acute bronchitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Diagnosis and treatment of acute bronchitis

A

clinical presentation. labs should be normal. CXR only warrented if the clinical picture is weird (fever) or you have focal exam findings. No sputum culture needed.
supportive treatment. no abx unless pt is old, immunocompromised, or has pertussis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

clinical presentation of bronchiolitis

A

kid under 2 with wheezing and airway obstruction from infection. May be hard to distinguish from a triggered astham attach. Peak is age 2-6mo in winter. leading cause of hospitalization in kids under 2. kids are tachypnic with increased use of intercostal muscles and retratctions. Expiratory wheeze with prolonged expiratory phase. crackles and mild hypoxemia. hyperventilation and peribronchial coughing.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

2 major causes of acute brionchiolitis

A

RSV and human metapneumovirus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

bronchiolitis pathophysiology

A

virus infects the airway epithelial cells leading to damage and inflammation of small airways. this yeilds edema, mucus, sloughed epithelial debris. You see obstruction and air trapping

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What are the risks of severe disease with bronchiolitis?

A

prematurity, low birth weight, age under 6-12 wks, chronig pulmonary disease, congenital heart disease, immunodeficiency.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Brionchiolitis treatment

A

supportive. Maybe bronchodilators? No abx. Riaviran may be used in severe case, but it is inhaled, hard to use, and teratogenic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

briochiolitis prevention

A

palivizumab: monocolonal Ab against RSV fusion glycoprotein. given once per month in RSV season among premies

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

community acquired vs. hospital acquired pneumonia

A

community acquired: found in people who haven’t had hospital care or long term care in last 14 days. If in hospital less than 72 hrs and become ill during hospital stay, this is also considered community acquired. hospital acquired is seen in people who have been in the hospital within the last 14 days.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

5 ways to gain access to the lung parenchyma

A
  1. aspiration (S. pneumo, H flu, gram neg rods, S aureus, actinomyces)
  2. infection of the upper airway with subsequent spread (RSV, chlamydia, mycoplasma
  3. direct inhalation of infection in lungs: TB, flu, fungi
  4. hematogenous: VZV, CMV, S aureus, septic pulmonary emboli
  5. contiguous spread from adjacent infection:
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Host defenses against pneumonia

A
  1. Mechanical: hairs and turbinates, branching of the tracheobronchial tree to trap particles and allow for clearance
  2. cough and gag reflex
  3. normal flora prevent pathogenic bacterial binding
  4. resident alveolar macrophages and surfactants
17
Q

Inflammatory response for pneumonia

A

IL1 and TNF trigger fever
IL8 and GSF recruit neutrophils
WBCs increase
purulent sputum production

18
Q

4 stages of classical pneumonia

A
  1. alveoli fill with fluid
  2. red hepatization: RBCs, polys, bacteria
  3. Grey hepatization: PMNs, fibrin, bacteria
  4. resolution: macrophages, fibrin, inflammatory response cleared