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Det Orala Ekosystemet > Onkogener > Flashcards

Onkogener Flashcards

1
Q

Cell proliferation

A

Celltillväxt + celldelning

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2
Q

Onkogen

A

En muterad gen som bidrar till att cancer utvecklas. Ex RAS

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3
Q

Mutation

A

Fel i nukleotiderna.

Nya/ borttappade nukleotider

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4
Q

Proto-onkogen

A

En gen som inte är muterad och fungerar som vanligt innan eventuell mutation sker

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5
Q

Kännetecken hos cancer

A

10 steg

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6
Q

Bibehålla proliferativ signalering

A

A) autokrin signal. (Producera egna tillväxtsignaler)

B) signalera till stromacell att producera signalmolekyler

C) ändrad typ och eller mängd av ytterreceptorer

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7
Q

Undvika tillväxthämmande signaler

A

A) ändra typ och eller mängd av receptorer

Eller stimulera storma celler att inte producera

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8
Q

Motstånd till celldöd

A

Undvika apoptos

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9
Q

Möjliggör replikativt odödlighet

A

Genom telomerer

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10
Q

Endokrina signaler

A

Hormon reglering tex insulin

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11
Q

Parakrina signaler

A

Lokal signalering tex vid sår

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12
Q

Autokrina signaler

A

Skickar ut signalmolekyl till sig själv

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13
Q

Synaptisk signalering

A

Exempel nervcell—> elektrisk potential

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14
Q

Kontaktberoende signalering

A

Mekanisk signalering ex tight junction

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15
Q

Extracellulära signaltyper

A
  1. Små/ hydrofoba kan passera genom cellmembran

2. Större molekyler som kräver receptorer

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Det Orala Ekosystemet (10 decks)

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