ophthalmology Flashcards

lecture 59 (36 cards)

1
Q

risk factors glaucoma

A

age (40+) or race
corneal thickness or eye injury
use of steroids or hypertension (can affect pressure)
nearsighted or farsighted
diabetes or sickle cell anemia (especially untreated)

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2
Q

symptoms of open

A

none in the early stage
patchy blind spots in peripheral vision
vision difficulty in central vision

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3
Q

diagnosis of open

A

measuring of IOP
testing for optic nerve damage
vision loss assessment
corneal thickness measurement
inspection of drainage canal

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4
Q

symptoms of closed

A

medical emergency!!
severe HA or blurred vision
severe pain or halos around light
NV or redness in eye/cloudy cornea

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5
Q

drugs that increase aqueous humor outflow

A

prostaglandins
rho kinase inhibitors
cholinergics

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6
Q

drugs that block aqueous humor production

A

beta blockers
carbonic anhydrase inhibitors

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7
Q

drugs that increase outflow and reduce production

A

alpha-2 agonists

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8
Q

how is open glaucoma treated?

A

either by increasing aqueous humor outflow, blocking aqueous humor production, or both

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9
Q

what drugs are prostaglandins?

A

latanoprost
bimatoprost
travoprost
tafluprost
bimatoprost

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10
Q

goal of prostaglandins

A

decrease IOP by 30%

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11
Q

warnings of prostaglandins

A

eyelash increase (both length/number)
darkening of eyelid, iris, skin, and eyelash

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12
Q

se of prostaglandin

A

blurred vision
stinging
light sensitivity

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13
Q

drug of rho kinase inhibitors

A

netarsudil/latanoprost

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14
Q

SE of rho kinase inhibitors

A

burning
corneal disease
conjunctival hemorrhage
conjunctival hyperemia

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15
Q

drugs of cholinergics

A

carbachol
pilocarpine

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16
Q

cholinergic warnings

A

use caution in patients with history of retinal detachment or corneal abrasion

17
Q

SE of cholinergics

A

corneal clouding
pupil constriction
hypotension
bronchospasm
cramping in the abdomen/GI distress

18
Q

beta blocker drugs

A

betaxolol
timolol
carteolol
levobunolol

19
Q

CI of beta blockers

A

sinus bradycardia
other heart related conditions
bronchospastic disease

20
Q

SE of beta blockers

A

blurred vision
stinging
bradycardia
breathing problems

21
Q

how would the SE of beta blockers be minimized?

A

closing eyes for 1-2 minutes

22
Q

carbonic anhydrase inhibitor drugs

A

dorzolamide/timolol (drop)
acetazolamide (oral)
brinzolamide/brimonidine (drop)
methazolamide (oral)

23
Q

warnings of carbonic anhydrase inhibitors

A

sulfonamide allergy

24
Q

SE of eye drop carbonic anhydrase inhibitors

A

blurred vision
burning
blepharitis
taste disturbance

25
SE of oral carbonic anhydrase inhibitors
ataxia confusion photosensitivity nausea metabolic acidosis
26
alpha-2 agonists drug
apraclonidine brimonidine brimonidine/timolol/brinzolamide
27
warnings of alpha-2 agonists
CNS depression
28
SE of alpha-2 agonists
blurred vision dry eyes xerostomia sedation/confusion conjunctival hyperemia (redness)
29
what is first line treatment of open glaucoma?
prostaglandins analogs beta blockers alpha-2 agonists (ish)
30
what is second line treatment of open glaucoma?
carbonic anhydrase inhibitors alpha-2 agonists (ish)
31
what is third line treatment for open glaucoma?
rho kinase inhibitors
32
what is the last line treatment for open glaucoma?
cholinergics
33
treatment of closed glaucoma
hyper osmotic agents surgery
34
hyperosmotic agents drug
mannitol (IV) glycerin (po)
35
surgery option
iridotomy --> tiny holes in iris to allow fluid drainage
36
what medications are safe to take after iridotomy?
anticholergics topiramate chronic steroids decongestants antidepressants