Opioid Analgesics And Antagonists Flashcards Preview

Neuro II Final > Opioid Analgesics And Antagonists > Flashcards

Flashcards in Opioid Analgesics And Antagonists Deck (16):
1

Codeine

Full agonist

Metabolites: hydrocodone and oxycodone

2

Fentanyl

Full agonist

Metabolites: alfentanil, remifentanil, sufentanil

3

Levorphanol

Full agonist

4

Meperidine

Full agonist

5

Morphine

Full agonist

Metabolites: hydromorphone* and oxymorphone

6

Tramadol

Full agonist

7

Methadone

Full agonist

8

Buprenorphine

Partial agonist

9

Butorphanol (k)

Partial agonist

10

Nalbuphine

Partial agonist

11

Naloxone (narcan ; IV)

Full antagonists

12

Naltrexone (oral)

Full antagonists

13

Tramadol##

Inhibits catecholamine reuptake

Can cause seizures if you take a lot

14

Meperidine###

Full agonist, eyes: pupil dilation (unique)

Normeperdine (a metabolite) is toxic and can cause seizures if it accumulates

Rarely given to pts now

15

Methadone##

Longer half life and better bioavailability than morphine

Pts addicted to opioids- give and it helps decrease peaks/troughs that drive them to seeking/abusing

16

Antidote for opioid OD

Naloxone (aka Narcan)- typical one given

Naktrexone- long duration of action (48 hrs)- given orally