Opioid Analgesics And Antagonists Flashcards Preview

Neuro II Final > Opioid Analgesics And Antagonists > Flashcards

Flashcards in Opioid Analgesics And Antagonists Deck (16)
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1
Q

Codeine

A

Full agonist

Metabolites: hydrocodone and oxycodone

2
Q

Fentanyl

A

Full agonist

Metabolites: alfentanil, remifentanil, sufentanil

3
Q

Levorphanol

A

Full agonist

4
Q

Meperidine

A

Full agonist

5
Q

Morphine

A

Full agonist

Metabolites: hydromorphone* and oxymorphone

6
Q

Tramadol

A

Full agonist

7
Q

Methadone

A

Full agonist

8
Q

Buprenorphine

A

Partial agonist

9
Q

Butorphanol (k)

A

Partial agonist

10
Q

Nalbuphine

A

Partial agonist

11
Q

Naloxone (narcan ; IV)

A

Full antagonists

12
Q

Naltrexone (oral)

A

Full antagonists

13
Q

Tramadol##

A

Inhibits catecholamine reuptake

Can cause seizures if you take a lot

14
Q

Meperidine###

A

Full agonist, eyes: pupil dilation (unique)

Normeperdine (a metabolite) is toxic and can cause seizures if it accumulates

Rarely given to pts now

15
Q

Methadone##

A

Longer half life and better bioavailability than morphine

Pts addicted to opioids- give and it helps decrease peaks/troughs that drive them to seeking/abusing

16
Q

Antidote for opioid OD

A

Naloxone (aka Narcan)- typical one given

Naktrexone- long duration of action (48 hrs)- given orally