Oral Manifestations of GI Disorders Flashcards Preview

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Flashcards in Oral Manifestations of GI Disorders Deck (17):
1

What is recurrent aphthous stomatitis?
Describe epidemiology

Canker sore-- occurs exclusively on non-keratinized mucosa (not dorsum of tongue, gingiva, hard palate)

Aphthous stomatitis usually develops after puberty with recurrences; no sex predilection

2

What is the difference between minor/major aphthous stomatitis?

1cm= major; heal with scarring

3

In which disorders do you see aphthous stomatitis?

Crohn's disease and ulcerative colitis (IBD)==> result from immune response to underlying disorder (not direct consequence of either disorder)

4

Describe histologic appearance of aphthous stomatitis

Mixed inflammatory response-- neutrophils, plasma cells, maybe eosinophils

5

Describe oral lesions in Crohn's patients (4)

Ulcerations
Localized/generalized erythema
Hyperplastic, polypoid or papular lesions
Non-caseating granulomas (50% cases)

6

What type of lesion is pathognomonic for Crohn's disease

Linear ulcerations

7

What types of lesions are seen ini UC?

Ulcerative lesions==> nonspecific and often prodromal

8

What are the oral manifestations of celiac disease? (2)

Ulcerations
Enamel pitting=> predominantly permanent teeth

Both are nonspecific

9

What is an oral manifestation that occurs in GERD?

Enamel erosion due to increasing acidity of oral cavity

10

What are oral manifestations of FAP (3) and HNPCC (1)?

FAP: osteomas, odontomas (mini-teeth), supernumerary teeth

HNPCC: fordyce granules (ectopic sebaceous glands that are white-yellow in color)

11

What is the histologic appearance of fordyce granules?

Sebaceous glands in oral mucosa

12

Describe the oral manifestations observed in Peutz Jeghers Syndrome

Hyperpigmentation/freckling of lips

This is pathognomonic for Peutz-Jeghers

13

What is pyostomatitis vegetans?

How does it present?

Oral manifestation of IBD or GI malignancy

They look hella nasty--"snail track lesions" but have minimal oral discomfort

14

Describe the histologic appearance of pyostomatitis vegetans

Separation of epithelium and accumulation of neutrophils and eosinophils within blister

15

What is treatment for pystomatitis vegetans? (2)

Treat GI disease
Systemic corticosteroid therapy

16

What is malignant acanthosis nigricans?

Unusual manifestation of GI cancer, other malignancies

Hyperkeratotic brownish patches in folds of skin with leathery texture-- usually not intraoral

17

Describe histologic appearance of malignant acanthuses nigricans

Hyperkeratotic epithelium with papillary architecture