Histology of Para-alimentary tract Flashcards Preview

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Flashcards in Histology of Para-alimentary tract Deck (15):

Parotid gland gland types:

Just serous-- glandular due to abundance of zymogen granules


Sublingual and submandibular gland types:

Both serous and mucinous


What is the function of the minor salivary glands?

Moisten the mucous membranes of the upper aero-digestive tract

Continous fluid secretion


Where are the minor salivary glands located?

Submucosa of oral cavity, nose, paranasal sinuses, pharynx, larynx, esophagus, upper airways


What are principle functions of liver? (2)

Metabolism (synthesis, storage and breakdown) of proteins, triglycerides, cholesterol, carbs, bile salts/acids, urea and heme
Degradation of endogenous and exogenous toxins
Bunch of reactions


Describe blood supply for liver

Describe drainage

Portal vein (70%; nutrient rich) and hepatic artery (30%; oxygen rich) enter at hilum/porta hepatic and ramify through branches into sinusoids

Drainage: Blood perfuses parenchyma via sinuosoids, which then drains into hepatic central veins to IVC


Describe lobule anatomy

Hexagonal shape with portal triads at edges; sinusoids lead to central vein


Describe three zones in sinusoid

From outside (1) to inside (3)....how close they are to blood supply


Know how to identify difference in appearance between central vein, portal vein hepatic arteriole and bile duct

Know both gross and histologically


What is a kuppfer cell? Describe it

Macrophage/monocyte cell of liver (an APC)

Tends to have a fatter nucleus and be more round than endothelial cell


What is the space of disse?

A perisinusoidal space around hepatocytes allowing for diffusion


Describe the two main categories of liver enzymes and the enzymes that belong to each category (2)

Hepatocyte integrity: AST, ALT
Biliary excretory function: GGT, alkaline phosphatase


What are exocrine and endocrine functions of pancreas?

Exocrine (80% volume): Production of digestive enzymes via secretory acini

Endocrine (2% gland): hormonal secretion regulating glucose metabolism via Islets of Langerhans


Describe difference in glycogen/glucose metabolism among hepatocyte zones

Zone 1 tends to be more involved than 2/3 as seen via a PAS stain for glycogen


What is the function of the gallbladder

Concentrate store and release bile via coordinated neural and hormonal stimuli:

Contraction of sphincter of do allows accumulation of bile from liver
CCK promoted gallbladder contraction