Histology of Para-alimentary tract Flashcards Preview

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Flashcards in Histology of Para-alimentary tract Deck (15):
1

Parotid gland gland types:

Just serous-- glandular due to abundance of zymogen granules

2

Sublingual and submandibular gland types:

Both serous and mucinous

3

What is the function of the minor salivary glands?

Moisten the mucous membranes of the upper aero-digestive tract

Continous fluid secretion

4

Where are the minor salivary glands located?

Submucosa of oral cavity, nose, paranasal sinuses, pharynx, larynx, esophagus, upper airways

5

What are principle functions of liver? (2)

Metabolism (synthesis, storage and breakdown) of proteins, triglycerides, cholesterol, carbs, bile salts/acids, urea and heme
Degradation of endogenous and exogenous toxins
Bunch of reactions

6

Describe blood supply for liver

Describe drainage

Portal vein (70%; nutrient rich) and hepatic artery (30%; oxygen rich) enter at hilum/porta hepatic and ramify through branches into sinusoids

Drainage: Blood perfuses parenchyma via sinuosoids, which then drains into hepatic central veins to IVC

7

Describe lobule anatomy

Hexagonal shape with portal triads at edges; sinusoids lead to central vein

8

Describe three zones in sinusoid

From outside (1) to inside (3)....how close they are to blood supply

9

Know how to identify difference in appearance between central vein, portal vein hepatic arteriole and bile duct

Know both gross and histologically

10

What is a kuppfer cell? Describe it

Macrophage/monocyte cell of liver (an APC)

Tends to have a fatter nucleus and be more round than endothelial cell

11

What is the space of disse?

A perisinusoidal space around hepatocytes allowing for diffusion

12

Describe the two main categories of liver enzymes and the enzymes that belong to each category (2)

Hepatocyte integrity: AST, ALT
Biliary excretory function: GGT, alkaline phosphatase

13

What are exocrine and endocrine functions of pancreas?

Exocrine (80% volume): Production of digestive enzymes via secretory acini

Endocrine (2% gland): hormonal secretion regulating glucose metabolism via Islets of Langerhans

14

Describe difference in glycogen/glucose metabolism among hepatocyte zones

Zone 1 tends to be more involved than 2/3 as seen via a PAS stain for glycogen

15

What is the function of the gallbladder

Concentrate store and release bile via coordinated neural and hormonal stimuli:

Contraction of sphincter of do allows accumulation of bile from liver
CCK promoted gallbladder contraction