Oral Mucosa 2 Flashcards

(57 cards)

1
Q

What branchial arch does the mucosa of the body of the tongue derive from?

A

BA 1

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2
Q

T/F: Tongue root mucosa is derived from BA 2

A

False- This mucosa is from BA 3

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3
Q

What lies beneath the lamina propria of the tongue?

A

Muscle. There is no submucosa present.

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4
Q

What cranial nerves convey taste?

A

CN VII, IX, X

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5
Q

Which CN provides somatosensory innervation to the anterior mouth?

A

CN V

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6
Q

Which CN provides somatosensory innervation to the posterior tongue/pharynx?

A

CN IX

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7
Q

What do A-beta fibers convey?

A

Touch

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8
Q

Pain is conveyed through A-delta and C fibers. T or F?

A

True

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9
Q

Which fiber responds to both painful and innocuous cooling?

A

C fiber

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10
Q

Which fiber responds to both painful and innocuous warmth?

A

A-delta fiber

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11
Q

What mechanoreceptor terminates b/t rete pegs (never enters the epithelium), and senses dynamic, rapidly adapting forces?

A

Meissner’s Corpuscles

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12
Q

Where do Merkel receptors terminate?

A

At the apices of rete pegs

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13
Q

What type of force do Merkel receptors detect?

A

Static forces

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14
Q

T/F: Free nerve endings always terminate in the lamina propria.

A

False- They can either terminate in the lamina propria or the epithelium

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15
Q

Do Merkel and Meisner receptors code for pain if the stimulus reaches noxious levels?

A

No, only mechanoreception. Free nerve endings carried by A-delta and C fibers deal with pain.

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16
Q

What are the 5 types of taste and an example of each?

A
Sweet-Sugars
Umami-Amino Acids
Salty-Sodium
Sour-Acids
Bitter-Coffee, Beer, (Notes say alkaloid, purine base, glycosides)
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17
Q

How is a taste bud oriented in regards to the basal lamina?

A

Right angle

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18
Q

What is the shape of a taste bud?

A

Goblet-shaped

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19
Q

T/F: All cells of the taste bud possess microvilli.

A

False-Only the Elongated cells possess them. (I looked up if all 3 types of elongated cells have microvilli and came to the conclusion that only Type I and II have them.–Google Books, “Taste and Smell: An Update”)

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20
Q

About how many taste buds are on the oral mucosa?

A

8,000

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21
Q

What are the percentages for taste buds for tongue, pharynx/larynx, and soft palate?

A

Tongue-68%
Pharynx/Larynx-27%
Soft Palate-5%

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22
Q

T/F: Circumvallate Papillae are located on the posterior 1/3 of tongue

A

False: They are located on the most posterior portion of the anterior 2/3 of the tongue

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23
Q

Where are fungiform papillae located?

A

Anterior 2/3 of dorsum of tongue

24
Q

Location of foliate papillae?

A

Lateral portion of tongue at most posterior portion of the anterior 2/3.

25
What papillae does the chorda tympani branch of CN VII (BA 2) innervate?
Fungiform Papillae
26
Taste buds are located on what surface of fungiform papillae?
Dorsal
27
About how many taste buds are on 1 fungiform papillae?
average of 3
28
On average, how many taste buds do filiform papillae contain?
0-no buds here
29
What type of fibers innervate filiform papillae?
Only Somatosensory-Merkel&Meisners (A-beta), free nerve endings (C, A-delta)
30
What CN innervates foliate papillae?
CN IX (BA 3)
31
What is location of taste buds on foliate papillae?
In trenches on sides, not on top like the fungiform papillae
32
Which papillae are most closely associated with Von Ebner's glands?
Foliate and Circumvallate
33
Where are circumvallate taste buds located?
In trenches on sides
34
What is the location of taste buds that mainly respond to deviations from isotonicity?
Larynx
35
What was main point of study regarding responses of individual fungiform papillae and taste?
Pretty much 1 fungiform can discriminate b/t multiple tastes.
36
Are taste stimuli undetectible on the front side of the tongue contralateral or ipsilateral to chorda tympani anesthesia?
Ipsilateral
37
Does chorda tympani nerve anesthesia effect "whole mouth" taste perception?
Very minimally b/c of the functional redundancy of the taste system makes it resilient to partial taste loss
38
According to study: Do all individuals have about the same number of fungiform papillae?
No, the number varies greatly person to person
39
Do all people have the same ability to taste different molecules? What about PTC?
Everyone has a different affinity to taste specific molecules. The ability to taste PTC is an inherited trait.
40
Name a specific bitter receptor.
Tas2r
41
What did she "impress" upon us in regards to the vegetable bitterness and intake studies?
Certain vegetables taste more bitter to those who are homozygous for the PTC-senstive form of tas2r38 and vice versa. This varying sensitivity has been shown to impact the intake of certain vegetables based upon bitterness
42
Where are perigemmal cells located on the taste bud?
Lateral aspect
43
What is the main function of basal cells of taste bud?
Renewal-very high turnover
44
Are type I elongated cells dark or light in EM views?
Dark
45
Which type of elongated cell has a suggested supportive role?
Type 1 Dark-stains for glial markers, supportive role.
46
T/F: Type 1 Dark cells have microvilli and synapse with a primary afferent nerve
False-They do have microvilli but do not synapse
47
Which elongated cells express receptors for taste and respond to taste stimuli?
Type II and Type III Light
48
Which taste(s) corresponds to Type II Light cells?
Bitter, Sweet, Umami
49
Which taste(s) corresponds to Type III Light cells?
Sour
50
T/F: Type III Light cells synapse with primary afferent nerve
True. Type II Light do NOT synapse with primary afferent
51
What is used as a non-synaptic taste transmitter for Type II cells? (Also Type III can do this as well)?
ATP
52
What intermediate filament protein is thought to reflect rapid turnover of taste receptor cells?
Keratin-19 (K19)
53
What appears at week 12 embryologically?
Taste Pores
54
When does the tongue appear?
Week 4
55
When do taste buds 1st appear?
Week 8
56
What happens in EW 8?
Lingual papillae develop, taste buds 1st appear
57
Glance at Enfamil/Nutramigen study, no questions posted.
Good luck