Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

Oral Histology > Oral Mucosa > Flashcards

Oral Mucosa Flashcards

(71 cards)

Start Studying
1
Q

What is the mouth, nasal passages, and GI tract lined by?

A

Mucous membrane

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What 2 tissues make up a mucous membrane?

A

Epithelium

Underlying Connective tissue

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What makes up the underlying connective tissue?

A

Lamina propria

Sometimes the submucosa

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What layer are blood vessels located in the mouth?

A

Lamina propria or Submucosa

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What layer are minor salivary glands located?

A

Submucosa

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Where are ducts from minor and major salivary glands located?

A

Travel through the connective tissue to communicate with the mucosal surface

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What are the functions of oral mucosa?

A

Protection
Aid in digestion
Sensory innervation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What are the types of protection the Oral mucosa provieds?

A

Barrier

Anti-microbial

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Barrier defense of oral mucosa

A

Epithelium provides a physical barrier for things to not come into contact with deeper underlying tissues

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Anti-microbial defense of the oral mucosa

A

Immune cells are found mostly in the lamina propria, but also found in the epithelium

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

B-defensins

A

Anti-microb secreted by teh superficial epithelium of the oral cavity
Large amount is secreted when there is an infection
Cysteine-rich, cationic molecule that binds to negative charges on bacterial membranes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

How does the oral mucosa aid in ingestion?

A

Provides flexibility and a moist surface, making chewing and swallowing easier

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Which is capable of more type sensation, oral mucosa, PDL, or pulp?

A

Oral mucosa

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What types of fibers innervate pulp/dentin and what type of sensation do they provide?

A

C, A-delta, A-beta = mostly pain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What types of fibers innervate the PDL, and what type of sensation do they provide?

A

C and A-delta = pain

A-beta = proprioceptive

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What types of fibers innervate the oral mucosa and what type of sensation do they provide?

A

A-beta = touch
A-delta and C = pain
A-delta and C = thermal
A-delta = taste

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What type of cells are found in oral mucosa epithelium

A

Stratified Squamous epithelium

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What occurs in the deep layers of the oral mucosa epithelium?

A

Location of cell division

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

What occurs at the superficial layers of oral epithelium?

A

This is where cells migrate, mature, become part of the surface, and then slough off

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

What is the turnover time for gingiva epithelium?

A

41-57 days

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

What is the turnover time for cheek epithelium?

A

25 days

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

What is the turnover time for taste buds?

A

10 days

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

What is the turnover time for junctional epithelium?

A

5-10 days

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

What is the cost/benefit of having fast turnover in epithelium

A

They can heal faster, but it also makes the tissues more vulnerable to conditions that affect cell division (chemotherapy, radiation, ulceration)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
What are the most numerous cells of the oral mucosa?
Keratinocytes (aka epithelial cells)
26
What are the non-keratinocytes found in the oral mucosa?
Merkel cells Melanocytes Langerhans (dendritic cells)
27
Merkel cells
Sensory cells in the basal layer of the epithelium
28
Melanocytes
Pigment cells in the basal layer of the epithelium
29
Langerhans (dendritic) cells
Immune cells in the supra-basal layers
30
T/F - Different oral regions are lined by keratinized v non-keratinized epithelium
True
31
Describe keratinized epithelium
No organelles Dehydrated Tougher
32
Describe non-keratinized epithelium
Has organelles | Felixble
33
What do all epithelial cells/keratinocytes contain?
Cytokeratin
34
Cytokeratins
Large multigene family of proteins | Assemble into intermediate filaments to provide cytoskeletal support - mechanically tough
35
What are the two major groups of cytokeratines?
``` Type I (acidic) Type II (basic) ```
36
Cytokeratin structure
Central helical core surrounded by non-helical ends Each cell expresses at least 2 cytokeratins (one of each type) They assemble into coiled heterodimers
37
What are the strongest cytokeratin structures?
Intermediate filaments
38
What are the intracellular components cytokeratins?
Desmosomes and Hemidesmosomes
39
What do keratin mutations create
Mutations to cytokeratins, which can lead to blistering in response to minor trauma
40
T/F - Different epithelial layers and tissues contain the same cytokeratins
False - Cytokeratins are characterisitic of the different layers and tissues
41
What can changes cytokeratin expression?
Cytokeratin expression can change with disease state | Mutations in cytokeratin genes can produce regionally specific diseases
42
Which is more permiable, keratinized or non-keratinized epithelium?
Non-keratinized
43
T/F - The amount of cytokeratin only increases in the supericial layers keratinized epithelium
False - The amount of cytokeratin increases towards the superficial layers of both types of epithelium
44
What are the biochemical properties of Keratinized cytokeratins
They promote aggregations | They promote binding to another molecule (fillagrin)
45
Describe the superficial layers of Keratinized epithelium
Very flat cells Dehydrated No organelles Packed with cytokeratin and fillagrin complexes
46
What are the biochemical properties of non-keratinized cytokeratins?
Do not promote aggregation | Can't complex with fillagrin
47
Describe the superficial layers of non-keratinized epithelium
Cells are not flat or dehydrated Retain nuclei Cytokeratin tonofilaments
48
T/F - The permiability differences between keratinized and non-keratinized are due to cytokeratins
False - desmosomes contribute and are somewhat more numerous in keratinized epithelium
49
Membrane coating granules
Membrane bound organelles in the cell, filled with glycoproteins 1st appear in upper prickle layer Released in more superficial layers to coat the cell Found in both keratinized and non-keratinized cells to serve as an intercellular barrier to aqueous substances (more effective in keratinized)
50
Describe Membrane thickening
Envelope of 15nm cross-linked protein sheath comprised of loricrin and other proteins Impermiable On the inner face of keratinocytes in the upper layers of both types of epithelium
51
What takes up the most volume of the lamina propria?
ECM
52
What cells are present in the lamina propria
Fibroblasts Macrophages Mast cells Other inflammatory cells
53
What makes up the ECM of the lamina propria
PGs, and PAGs Glycoproteins (fibronectin) Collagen (types I and III) Elastin
54
Describe the epithelial/connective tissue interface
Scalloped | -has epithelial rete pegs, connective tissue papillae, and paipillary and reticular layers
55
Lining mucosa epithelium type
Non-keratinized
56
Describe the thickness of the epithelium in the buccal mucosa v the floor of the mouth
Buccal = thick (.5mm) | Floor of mouth = thin (.1mm)
57
Clinical implications of lining mucosa
Incisions more likely to gape and need to be sutured | Injections are less painful
58
Masticatory mucosa epithelium type
Keratinized
59
T/F - Lining epithelium has submucosa
True - it usually does
60
T/F - Masticatory mucosa has submucosa
False - it varies, but usually only in the hard palate
61
Clinical implications of the masticatory mucosa
Incisions don't gape and may not require suturing | Injections are more painful
62
What are the three areas of the lip region?
Exterior skin Vermillion zone Labial mucosa
63
Exterior skin of lip
Keratinized Thinnest Sweat glands Hair follicles
64
Vermillion zone
Keratinized Thin Blood vessels close to surface No sweat or mucous glands
65
Labial mucosa
Non-keratinized Thicker Mucous glands
66
Sulcular epithelium
Part of free gingiva, which faces the tooth | Gernerally not keratinized
67
Junctional epithelium
Forms a ceal around the tooth Oriented along the long axis of the tooth Highly permiable
68
What are the 2 basal lamina of the junctional epithelium
External (JE/lamina propria) | Internal (JE/tooth)
69
What supplies vasculature for the maxilla?
Superior alveolar and palatine arteries
70
What supplies vasculature for the mandible?
Inferior alveolar a Buccal a Mental a Sublingual aa
71
What are the 3 routes blood can reach its destination in a tooth?
PDL Interdentinal septa Oral mucosa

Oral Histology (12 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions