Oral Surgery Flashcards

(312 cards)

1
Q

Trigeminal nerve (CN V)

A

largest CN, the principal general sensory nerve to the head and face, sensory and motor

motor root exits foramen ovale

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

does CN V have parasympathetics at its origin?

A

NO

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

mandibular division of CN V innervates how many muscles?

A

8

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

CN V somatic SENSORY bodies of the ganglion’s sensory fibers enter the 3 divisions:

A

V1 Ophthlamic - ORBIT and SKIN above eyes

V2 Maxillary - nasal cavity, max teeth, palate, skin over maxilla

V3 Mandibular - mandible, TMJ, mand teeth, FOM, tongue, skin of mandible

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

CN V, axons of neurons enter the __ through the sensory root and terminate in 1 of 3 nuclei of the trigem sensory nuclear complex (3)

A

PONS

  1. mesencephalic - proprioception ex. muscle spindle
  2. main sensory - general sensation ex. touch
  3. spinal nucleus - pain and temp
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

proprioceptive fibers from muscles and TMJ found in which CN V division?

cell bodies of proprioceptive 1st order neurons are found in the __ nucleus

A

V3

mesencephalic NOT the trigem ganglion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

branchiomeric motor fibers innervate which muscles?

A
Temporalis
Masseter
Medial and Lateral Pterygoids
Anterior belly of the Digastric
Mylohyoid
Tensor tympani
Tensor veli palatini
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Mandibular Div (V3) of the trigem passes through __ and supplies sensory/motor? innervation to these muscles

A

foramen ovale
MOTOR

to tensor veli palatini, tensor tympani, muscles of mastication (temporalis, masster, lateral and medial pterygoids), anterior belly of digastric, mylohyoid muscles

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

CN V3 sensory innervation (4 nerves)

A
  1. long buccal (sensory only) -> cheek, md buccal gingiva
  2. auriculotemporal (sensory only) -> TMJ, auricle, external auditory meatus
  3. lingual (sensory only) -> FOM, mand lingual gingiva, anterior 2/3 tongue
  4. inferior alveolar nerve (sensory & motor!) -> mand teeth, chin skin, lower lip
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

massteric nerve is a branch of CN V3 that carries sensory/motor? fibers to the TMJ’s anterior portion

A

sensory

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

auriculotemporal nerve is a branch of VN V3 that provides major sensory/motor? innervation to the TMJ’s posterior portion

also transmits pain in the TMJ __ and __

A

SENSORY

pain in TMJ capsule and disc periphery

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

nerve to mylohyoid muscle is a branch of the mandibular nerve (V3), functions to?

A

elevate hyoid bone, base of tongue, FOM

-sublingual gland is superior to mylohyoid muscle

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

when the floor of the mouth is lowered surgically, the __ and __ muscles are detached

A

mylohyoid & genioglossus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

suprahyoid muscles (4) and their innervations

A
  1. Digastrics (ant and post) - CN V3 (ant), CN VII (post)
  2. Mylohyoid - CN V3
  3. Geniohyoid - C1 via hypoglossal CN XII
  4. Stylohyoid - CN VII
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

infrahyoid muscles (4) and their innervations

A
  1. Thyrohyoid
  2. Omohyoid
  3. Sternohyoid
  4. Sternothyroid

all innervated by Ansa Cervicalis (loop formed by branches of cervical plexus C1, C2, C3)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

hypoglossal nerve is a motor nerve supplying what muscles?

A

all intrinsic and extrinsic tongue muscles EXCEPT palatoglossus (vagus nerve)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

unilateral lesions of the hypoglossal nerve cause deviation of the protruded tongue to the affected or opposite side?

A

affected side, cause of lack of fxn of genioglossus on diseased side

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

if the __ muscle is paralyzed, the tongue can fall back and obstruct the oropharyngeal airway

A

genioglossus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

carotid sheath location? what does it contain?

A

lateral boundary of retropharyngeal space at level of oropharynx, deep to SCM muscle

contains carotid arteries, internal jugular vein, vagus nerve, deep cervical lymph nodes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

when you retract the carotid sheath, the __ __ __ stays because it is not within the sheath

A

cervical sympathetic trunk

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

facial vein unites with the __ vein below the border of the mandible and empties into the internal jugular vein

A

retromandibular

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

internal jugular vein descends through neck inside carotid sheath, eventually to forms the

A

superior vena cava -> right atrium

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

max 1st molar innervated by what nerves

A

middle superior and posteiror superior alveolar

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

what injection must you give to ext all molars and 2nd PM?

A

long buccal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
greater (anterior) palatine nerve is a branch of the maxillary (CN V2) that innervates? GP foramen is where?
soft tissue to posterior 2/3 of hard palate -> canine (overlaps with nasopalatine) btw 2nd and 3rd max molar, ~1 cm from palatal gingival marign toward midline
26
which cranial nerves have parasympathetic activity?
III VII IX X
27
Cranial nerves (12)
I - olfactory - smell II - optic - sight III - oculomotor - eyeball movement, pupils, vision IV - trochlear - eyeball movement V - trigem - sensation to face, scalp, teeth, muscles of mastication, mandible movement VI - abducens - eyeball movement VII - facial - taste, face muscles, saliva secretion VIII - vestibulocochlear - hearing, equilibrium IX - glossopharyngeal - taste, sensory for cardiac, respiratory, bp reflexes, pharynx contraction, saliva X - vagus - sensory in cardiac, respiratory, bp reflex, larynx, decr HR, peristalsis, incr. digestive secretions XI - accessory - contract neck and shoulder XII - hypoglossal - motor to tongue except palatoglossus
28
external carotid artery supplies? passes through the __ gland
most of head and neck cept brain through parotid salivary gland terminates as max and superficial temporal arteries
29
maxillary artery supplies what? 3 branches
max and mand teeth, muscles of mastication, palate, nasal cavity IA artery -> mand teeth PSA artery -> post max teeth ASA & MSA -> ant max teeth
30
venous return of both dental arches is?
pterygoid plexus of veins
31
greater (descending) palatine artery supplies?
hard palate, gingiva of max teeth and lateral nasal wall lesser palatine also does tonsils
32
lingual artery supplies? arises from? terminates as?
blood to tongue (also gets blood from tonsillar branch of facial artery and ascending pharyngeal artery) also supplies FOM arises from external carotid artery, terminates as deep lingual artery does NOT accompany its nerve throughout its course
33
lingual artery branches (4)
suprahyoid dorsal lingual deep lingual - anterior 2/3 tongue sublingual
34
inferior alveolar nerve and artery, and lingual nerve are found in the __ space?
PTERYGOMANDIBULAR SPACE btw medial pterygoid and ramus of mandible IA nerve passes lateral to sphenomandibular ligament
35
tongue sensory innervation
lingual nerve (branch of V3) - ant 2/3 tongue glossopharyngeal (CN IX) - post 1/3, vallate papillae, tonsil, nasopharynx, pharynx vagus (CN X) via internal laryngeal nerve - near epiglottis facial nerve (CN VII) via chorda tympani - taste to ant 2/3
36
facial nerve CN VII exits cranium through __ and extends laterally around mandible thorugh the __ gland
stylmastoid foramen parotid gland
37
fxns of facial nerve
1. motor - muscles of expression, post belly digastric, stylohyoid, stapedius 2. sensory (proprioception) - muscles of facial expression 3. motor (parasympathetic) - tear secretion from lacrimal gland, salivary from sublingual and submand glands 4. sensory (taste and sweet) - taste buds ant 2/3 tongue, FOM, palate
38
Parotid gland is a pure __ gland supplied by general visceral efferent (motor) nerve fibers of the __ nerve. Drained by? supplied by what artery? lymphatic drainage?
SEROUS, glossopharyngeal nerve Stenson's duct - pierces buccinator, crosses masster where it opens opposite max 2nd molar external carotid artery lymph -> parotid nodes to deep cervical lymph nodes
39
the only other adult salivary glands purely serous
Von Ebner's - around circumvallate papilla of tongue - fxn to rinse food away from papilla
40
__ is a viral disease of the parotid gland
mumps
41
Wharton's duct (submandibular) is closely related to what nerve? innervated by? blood supply from?
LINGUAL NERVE parasympathetic secretomotor fibers from FACIAL NERVE FACIAL ARTERY
42
sublingual gland is the smallest salivary gland that contains mostly ___ acini
MUCOUS - in FOM below tongue, close to midline - has many small RIVIAN ducts - secretory units are mucous secreting with serous demilumes
43
lymphatic drainage from the sublingual and submandibular glands goes to what lymph nodes
submandibular, deep cervical
44
sometimes the numerous sublingual ducts join to make a main excretory duct called __ that empties into the __ duct
Bartholin's Duct -> submandibular
45
in the H&N, all lymph ultimately rains into the __ lymph nodes
deep cervical - form a chain along course of the internal jugular vein - efferent lymph vessels join to form jugular lymph trunk, drains into thoracic duct or right lymphatic duct
46
regional lymph nodes (3)
1. parotid 2. submandibular - max and mand teeth, ant 2/3 tongue, paranasal sinuses 3. submental - mand incisors and gingiva, tip tongue, FOM, center lip
47
maxillary sinuses open into innervation?
hiatus semilunaris max division of trigem nerve (CN V2 - incl ASA, PSA, MSA, infraorbital)
48
antibiotics to treat sinus infxns
ampicillin - sinusitis from upper respiratory infxns penicillin and amoxicillin - sinusitis caused by odontogenic foci
49
max sinus communication if tooth or large fragment displaced, what do you do?
if small then just allow blood clot if fragment then remove it, if you can't get it thru socket then use Caldwell-Luc approach
50
integrity of max sinus floor is at greater risk with surgery removing a single remaining max molar cause of
possible ankylosis
51
pterygopalatine fossa is a small space where? what nerve and artery passes through?
behind and below orbital cavity max nerve (V2) and artery
52
buccinator originates from 3 areas: what arteries supply it? action?
pterygomandibular raphe (btw buccinator and superior constrictor), maxillary and mandibular alveolar processes facial and maxillary arteries action - compress cheeks against molars for sucking and blowing
53
these muscles are the primary protractors of the mandible
lateral pterygoids -open and protrude, mandible side to side ex. right lateral movement, the LEFT is the mover
54
mandible deviates toward/away site of injury in condylar ankylosis, unilateral condylar fracture, latearl pterygoid injury
TOWARD
55
mandible deviates toward/away site of injury in cases of condylar hyperplasia
AWAY
56
what muscle forms the roof of the pterygomandibular space?
lateral pterygoid
57
masticator space is composed of what 3 spaces? infxns are almost always of dental origin from what region? symptoms?
masseteric, pterygomandibular, temporal mandibular molar region TRISMUS, pain, swelling
58
needle tract infxn after IA block initially involve what space?
pterygomandibular
59
most definite clinical sign indicating extension of odontogenic infxn into masticator space
TRISMUS | -can also be caused by passing needle through medial pterygoid muscle during IA block
60
temperomandibular joint is the articulation btw mandibular condyle and squamous portion of what bone?
temporal
61
TMJ components (4)
1. mandibular condyle (condyloid process) 2. articular fossa (mandibular or glenoid) 3. articular eminence (articular tubercule) 4. articular disc (meniscus)
62
condyle surface is covered with
vascular layer of fibrous CT
63
articular fossa (mandib or glenoid)
concave fossa, anterior 3/4 of larger mandib fossa NON-FUNCTIONING
64
articular eminence (articular tubercule) is a
CONVEX ridge lined with fibrous CT (fibrocartilage) FUNCTIONAL and articular portion of the TMJ
65
articular disc is
bioconcave, saddle shaped, made of fibrous CT - central intermediate zone separates anterior and posterior bands - posterior band has RETRODISCAL tissue/bilaminar zone which is VASCULAR and INNERVATED - anterior band is thinner, contiguous with capsular, condyle, superior belly of lateral pterygoid
66
muscles acting on TMJ
masseter, temporalis, pterygoids, digastric
67
3 TMJ ligaments are
1. Temperomandibular (lateral) 2. Stylomandibular 3. Sphenomandibular
68
Temperomandibular ligament fxn?
major one from articular eminence to condyle, the ONLY one that directl ysupports TMJ capsule -prevents posterior and inferior displacement of condyle
69
Stylomandibular ligament
accessory ligament, separates infratemporal from parotid region, located on POSTERIOR border of mandible
70
Sphenomandibular ligament
accessory ligament, located on MEDIAL surface of mandible
71
4 arteries that vascularize TMJ
1. Middle meningeal (branch of maxillary, terminal branch of external carotid) 2. Ascending pharyngeal 3. Deep auricular 4. Superficial temporal (terminal branch of external carotid)
72
TMJ syndrome divided in 3 categories
1. Myofascial pain 2. Internal derangement (disc displacement) 3. Degenerative join disease (osteoarthritis)
73
what's the syndrome that's the most common cause of TMJ pain?
myofascial pain dysfunction (MPD) - involves muscles of mastication - STRESS related - responds to night guard
74
internal derangement (disc displacement) is most common direction for disc to be displaced?
abnormal relationship of articular disc to condyle, fossa and articular eminence anteriorly - retrodiscal tissue (bilaminar zone) becomes abnormally stretched
75
if posterior band returns to normal position then this condition is called
anterior displacement with reduction | "pop" or "click"
76
subluxation (dislocation or open lock) is when
pt can't close mouth
77
disc displacement WITH redxn is when signs?
disc is out of place, hear a "click", painless patient has normal opening or "S" shaped, TMJ is only ROTATING (not translating), reciprocal clicking on opening and closing -on closing, the disc is forward to condyle
78
disc displacement WITHOUT reduction (closed lock) is when jaw deviates toward/opposite affected side? what direction are disc displacements?
clicking and opping is gone with limited opening and pain, a HARD-END feel deviates TO affected side NO reciprocal click most displacements -> ANTERIOR and MEDIAL
79
most common cause of restricted mandibular movement is
disc interference disorders
80
best way to palpate posterior aspect of the condyle is?
EXTERNALLY over posterior surface of condyle with mouth open | -palpate laterally in front of external auditory meatus while pt opens and closes
81
what is the best incision to expose the TMJ?
preauricular anterior to external ear, parallel to superficial temporal artery, be careful of facial nerve
82
__ approach is the standard to approach the mandibular ramus and neck of the condyle
Submandibular (Risdom)
83
the most common cause of TMJ ankylosis
TRAUMA
84
most common complication of rheumatoid arthritis
ankylosis
85
control of __ is vital to tx any pt with a facial fracture
airway
86
highest incidence of fractures occurs in what population
young males 15-24, trauma
87
3 muscle groups displace the condyles
1. masseter, medial pterygoid, temporalis - ELEVATE mandible during mastication, causes UPward displacement of proximal segment 2. digastric, mylohyoid, geniohyoid, lateral pterygoid - DEPRESS mandible and displaces DISTAL segment inferiorly and posteriorly 3. lateral pterygoid - FORWARD displacement of condylar head when the condylar neck is fractured
88
30% of fractures in the mandible happen in the 25% in the 22% in the 17% in the
1. ANGLE - proximal segment usually displaced anteriorly and superiorly 2. condylar neck 3. symphysis (chin) 4. body of mandible 5. ramus (2%) 6. coronoid process (1%)
89
on opening, pt's mandible deviates toward/opposite injury?
TOWARD
90
most common pathognomonic sign of mandibular fracture is
MALOCCLUSION
91
open reduction is? most common site is? indications?
the reduction of a fractured bone by manipulation after incision into skin and muscle over fracture site mostly at ANGLE of mandible best when teeth are missing in one or more of the fractured segments, when there's continued gross displacement of the segments
92
condylar neck fractures best treated by what method?
CLOSED reduction
93
closed reduction is? intermaxillary fixation is?
rdxn of fractured bone by manipulation without incision into skin applying wires or elastics btw jaws, most common is PRE-FAB arch bars
94
bilateral sagittal split osteotomy most common to correct?
mandibular retrognathia (Class II malocclusion) split mandible can be advanced or set back *position of condyle is UNCHANGED
95
vertical ramus osteotomy is used to correct
mandibular PROgnathism
96
body osteotomy is used to correct
``` mandibular PROgnathism (Class III malocclusion) -ext mand teeth bilaterally (usually PMs) ```
97
ways to immobilize a fracture (4)
1. Barton bandage 2. Intermaxillary fixation (IMF) 3. external skeletal fixation 4. Direct intraosseous wiring + IMF, traditional method after OPEN RDXN
98
greenstick fracture
mand fracture that extends only thru cortical portion of bone without complete fracture; most common in KIDS
99
classifications of mandibular fractures (3)
1. simple - 2 parts with no external communication (closed) 2. compound - communicates with outside (open), most common complication is INFECTION 3. comminuted - multiple fractures of a single bone that can be either single or compound
100
unfavorable fracture occurs if fracture line results in ___ favorable fracture occurs if fracture line __
muscle pull displacing the fracture segment prevents displacement of fracture by muscle pull
101
midfacial fractures affect these 3 structures
maxilla zygoma nasoorbital ethmoid complex
102
6 types of midfacial fractures 1. LeFort I 2. LeFort II 3. LeFort III 4. Zygomatic complex 5. Zygomatic arch 6. Nasoorbital Ethmoid
1. LeFort I - HORIZONTAL, causes OPEN BITE, used to correct Mx RETROgnathia 2. LeFort II - PYRAMIDAL, PARESTHESIA common over infraorbital nerve 3. LeFort III - TRANSVERSE or CRANIOFACIAL dysfunction, restricted mandibular movement 4. Zyogmatic complex - most common, can have paresthesia, hematoma in sinus, impaired ocular muscle 5. Zygomatic arch - no probs 6. Nasoorbital Ethmoid
103
what are the 1st and 2nd most common fractures of facial bones?
1. nasal | 2. zygomatic bone
104
signs and symptoms of zygomatic fracture
binocular diplopia, trismus, ipsilateral epistaxis
105
what view is best to evaluate orbital rim areas?
Water's view
106
symptoms of fracture of infraorbital rim?
numb upper lip, cheek, nose on affected side
107
3 radiographic views for midfacial fractures
1. Water's 2. PA skull 3. submental vertex
108
blows to the maxilla drive the maxilla in what direction? results in what kind of bite?
back and down -> open bite or impinged airway
109
segmental osteotomy is?
maxilla sectioned into 2+ pieces
110
fracture healing (4)
1. Endosteal proliferaiton - in bone 2. Periosteal proliferation - in CT 3. Primary (bone to bone) healing - endosteal and periosteal proliferation 4. Secondary bone healing - mostly endosteal proliferation
111
3 phases for healing bone
1. hemorrhage - first 10 days 2. callus formation - in 10-20 days, then a secondary callus 3. functional reconstruction - line up Haversion systems, bold will be molded, takes 2-3 years
112
4 reasons fractures don't heal
1. ischemia 2. excess mobility 3. interposition of soft tissue 4. infection
113
___ is the most of often sequela of fractures
FAT embolism
114
3 types of inappropriate healing
1. delayed-union: satisfactory healing 2. non-union: failure of segments to unite properly 3. mal-union: can be delayed or complete union in an improper position
115
Geudel's stages of general anesthesia (4)
1- Amnesia & Analgesia - best monitor is VERBAL 2- Delirium/Disinhibition & Excitement - loss of consciousness, onset of total anesthesia 3- Surgical Anesthesia - regular pattern of breathing, total loss of consciousness, 4 planes, spinal reflexes depressed, no pain reflexes 4- Premortem or Medullary Depression - signals danger, dilated pupils, cold skin, low bp, cardiac arrest imminent, severe respiratory and cardiovascular depression
116
3 agents for surgical anesthesia
cyclopropane - good muscle relaxant halothane - not good muscle relaxant, not good analgesic, halogenated hydrocarbons are assoc. with liver damage if toxic doses are used methoxyflurane - good muscle relaxant, respiratory depressant, good analgesic
117
ASA classes (6)
I - healthy II - mild systemic disease III - severe disease not incapacitating IV - severe systemic disease, threat to life V - moribound pt not expected to survive without operation VI - brain dead
118
elements of general anesthesia include (4)
analgesia relaxation hyporeflexia narcosis
119
__ is the last area of the brain depressed during general anesthesia
medulla | -contains cardiac, vasomotor, respiratory centers of the brain
120
most reliable sign of "oxygen want" is
increased pulse rate | cyanosis may also be present
121
most common emergency during outpatient general anesthesia is
respiratory obstruction
122
best anesthetic technique used in OS to avoid aspiration of blood or other debris when a pt is under general is
endotracheal intubation with pharyngeal packs
123
pt with __ infxn is contraindicated in general anesthesai
acute respiratory
124
Induction is
starts with admin of anesthetic and continues until desired level of pt unresponsiveness is reached rate and recovery depends on rate of change of tension in tissue, blood supply to lungs, pulmonary ventilation, concentration of anesthetic influence
125
Recovery is
when surgery is complete and delivery of anesthetic is terminated; ends when anesthetic is eliminated in the body
126
dissociative anesthesia
reduces anxiety and produces a trance-like state where the person is not asleep but feels separated from their body, good for KIDS, they usually don't remember, can have intense dreams or hallucinations
127
__ is the primary med used in dissociative anesthesia
KETAMINE, but usually give them a sedative first to reduce anxiety
128
local anesthetics are most effective in tissue about pH __ cause __
7 (alkaline) | locals are alkaloid bases combined with acids to make water-soluble salts
129
local anesthetics affect the nerve membrane by INCR/DECR? membrane's permeability to Na+ and INCR/DECR membrane's excitability
DECR membrane permeability DECR membrane's excitability bind to inactivation gates of fast voltage gated Na channels K, Ca, Cl conductances are unchanged reversibly block nerve impulse conduction and produce reversible loss of sensation
130
which nerve fibers are affected first by local? and last?
small NONmyelinated nerve fibers (pain, temp) > touch > proprioception > skeletal muscle tone
131
max. allowable dose of 2% lido with 1:100000 epi? carbo with no epi? max dose of epi for cardiac-risk pt?
3. 2 mg/lb or 7 mg/kg 3. 0 mg/lb 0. 04 mg (if 1:50000 then 1 carp, if 1:100000 then 2 carps, if 1:200000 then 4 carps) there is 0.018 mg epi in each carp of 2% lido with 1:100000 epi
132
1 cc 2% lido with 1:100000 epi has how much ``` mg lido? mg epi? mg NaCl? mg sodium-metabisulfate? mg methylparaben? ```
``` 20 mg lido 0.01 mg epi 6 mg NaCl 0.5 mg sodium-metabisulfate (preservative to stabilize epi) 1 mg methylparaben ```
133
allergic rxns are more common in esters or amides?
esters usually caused by an antigen-antibody rxn
134
PABA esters include
``` procaine (novocain)* was the prototype tetracaine/pontocaine (most common) propoxycaine (ravocaine) benzocaine (monocaine) cocaine ```
135
ester local anesthetics undergo rapid biotransformation in __ amides undergo biotransformation where?
blood plasma hydrolysis to PABA by the enzyme pseudocholinesterase (can't detox ester agents at a normal rate so use amides instead) amides in LIVER by microsomal enzymes
136
amide local anesthetics include
``` prilocaine (citanest) bupivicaine (marcaine) LIDOCAINE/XYLOCAINE (most common) mepivacaine (carbocaine) etidocaine (duranest) ```
137
what do you use for pts allergic to esters and amides?
diphenhydramine
138
local anesthesia works by?
reducing anxiety and sensitivity during the procedure
139
__ is the local anesthetic that may manifest toxicity clinically by initial depression and drowsiness
lidocaine | -usually it's stimulation first
140
what 2 anesthetics can show cross-allergenicity?
lido and mepivacaine
141
first clinical sign of mild lidocaine toxicity is?
nervousness related to CNS excitation
142
how do you tx sustained convulsive rxns to locals?
oxygen | diazepam IV
143
side effects of lido systemic absorption
tonic-clonic convulsions respiratory depression decreased CO
144
4 reasons why vasoconstrictors (ex. epi) are placed in locals
1. prolong duration of action* 2. reduce toxicity 3. reduce rate of vascular absorption by causing vasoconstriction 4. more profound anesthesia by incr. concentrations at nerve membrane
145
do vasoconstrictors reduce the change of developing an allergic rxn?
NO
146
3 anesthetics that contain epi
lido prilo marcaine
147
what anesthetic contains levonordefrin (neo-cobefrin)? which one has norepi?
mepivacaine procaine
148
vasoconstrictors act at what receptors to constrict arterioles? cocaine is an instrinsic vasoconstrictor that does what?
alpha receptors increases PRESSOR activity of both epi & NE
149
local anesthetics depress small/big? myelinated or non? nerve fibers FIRST and what last?
small non-melinated first then large, myelinated fibers last variations depend on nerve diameter and distance btw nodes of Ranvier
150
clinically, order of loss of nerve fxn from a local anesthetic is (5)
pain - temperature - touch and pressure - proprioception - skeletal muscle tone
151
what is the drug of choice for managing an acute allergic rxn involving bronchospasm and hypotension?
epi
152
inhalation anesthetic with fastest onset it inhibits what enzyme that is required for vit B12 production?
nitrous oxide - poorly soluble in blood - in surgery provides light anesthesia inhibits methionine synthetase
153
cons of N2O inhalation of 100% oxygen is contraindicated in a pt with what condition?
nausea, diffusion hypoxia COPD
154
N20 contraindications
hypoxemia, respiratory disease, emotional instability, contagious diseases OK for pregnant pt
155
N20 works where? organic or inorganic? excreted where? main effect on what systems? first symptom is?
CNS, INORGANIC, excreted by lungs (unchanged) reticular activating and limbic systems tingling of hands
156
neurolept analgesia only produces an unconscious state if __ is also administered
nitrous oxide
157
neuroleptic (droperidol) + narcotic analgesic (fentanyl) is
neurolept ANALGESIA (conscious)
158
neuroleptic + narcotic analgesic + N2O is
neurolept ANESTHESIA
159
nitrous oxide and ethylene are useful only for __ and __
sedation and analgesia N2O: ventricular fibrillation is LEAST LIKELY to occur with nitrous ethylene: rapid induction and recovery, but explosive and stinks
160
primary danger with using N2O > 80% conc. is
hypoxia
161
desflurane is
inhalation anesthetic, but irritates airway
162
SPEED of inhalation induction of anesthetics depend on 5 things
1. gas solubility* (more soluble, slower rate of induction) 2. inspired gas partial pressure 3. ventilation rate 4. pulmonary blood flow 5. arteriovenous conc. gradient
163
admin of inhalation anesthetic is usually preceded by administration of what drug
IV or intramuscular admin of a short-acting sedative hypnotic (often a BARBITURATE)
164
barbiturates do what to the CNS? 2 major effects? drugs to avoid in pts taking barbiturates? last tissue to become saturated? properties?
DEPRESS the CNS effects - sedative, hypnotic avoid - phenothiazines, alcohol, antihistamines, antihypertensives FAT is the last to be saturated cause it's not as vascular properties - respiratory depression, induction of liver microsomal enzymes, tolerance development, suppression of REM sleep, hyperanalgesia (incr sensitivity to pain)
165
most effective agent in initial tx of respiratory depression from overdose of barbiturates is
oxygen under positive pressure
166
most resistant part of CNS under general anesthesia is the
MEDULLA OBLONGATA
167
most controllable route of admin of general anesthetic is
inhalation
168
most common drug used to attain general anesthesia is most common side effect?
brevital (methohexital) -an IV barbiturate, induce anesthesia in short surgery as supplement to other aneshetics side effect - hiccoughs
169
malignant hyperthermia is what kind of condition? characterized by?
autosomal dominant inherited condition, life threatening, acute pharmacogenetic disorder in pts undergoing general anesthesia sudden rapid rise in body temp, incr. muscle metabolism (tachycardia, tachypnea, sweating, cyanosis, incr CO2 production, muscle rigidity)
170
the only drug that treats malignant hyperthermia
dantrolene
171
optimum site for IV sedation is what vein? avoid entering what artery?
median cephalic vein | avoid brachial artery
172
IV sedation usually with what drug? 3 common signs that indicate correct level of sedation has been reached?
Valium (diazepam) signs - blurred vision, slurring of speech, 50% ptosis of eyelids (Verrill's sign)
173
phlebitis (thrombophlebitis) of a vein after admin of IV valium is usually due to __ in the mixture clinical observations of phlebitis? (4)
propylene glycol obs - vessels are hard, sensitive to pressure, area is erythematous and warm, limb is pale/cold/swollen
174
scopolamine is a drug structurally similar to __ good for preventing __
acetylcholine good for motion sickness - depresses CNS, a sedative and anti-spasmodic - rdxn of secretions by competitive block of ach and other cholinergic stimuli
175
anticholinergic drugs work by:
interfering with binding of Ach at its receptor - categorized by ionization state of nitrogen (affects ability to penetrate CNS) - it's an anti-sialogue (decreases saliva!)
176
tertiary anticholinergic compounds include?
atropine, benztropine, scopolamine - atropine is contraindicated for nursing mothers and pts with glaucoma (atropine causes MYDRIASIS, dilated pupils) - these decr saliva flow and secretion from respiratory glands
177
quaternary anticholinergic compounds include?
glycopyrrolate, ipratropium, probanthine - can't penetrate CNS
178
Air volumes 1. TV 2. RV 3. ERV 4. IRV 5. VC 6. FRC
1. tidal - air inhaled 2. residual - what doesn't participate in ventilation 3. expiratory reserve - what can be exhaled in addition to TV 4. inspiratory reserve - what can be inhaled in addition 5. vital capacity - total lung capacity 6. functional reserve capacity - air left in lungs at end of expiration
179
pulmonary volumes and capacity or __ % less in females than males
20-25
180
laryngospasm is a how do you manage?
acute spasm of vocal cords and epiglottis manage by applying oxygen under positive pressure and aministering succinylcholine
181
universal sign of laryngeal obstruction is? what do you administer?
STRIDOR (crowing sounds) give epi and oxygen
182
if oxgen doesn't get to lungs, blood, brain, permanent neurologic damage occurs in how many minutes?
3-5
183
tracheotomy is for cricothyrotomy for
long-term airway maintenance EMERGENCY airway, ex. anaphylactic rxn
184
in an IA block, needle passes through mucous membrane and what muscle? and lies lateral to what muscle?
passes through BUCCINATOR and is lateral to the MEDIAL PTERYGOID -if it goes posterior at level of mandibular foramen, it penetrates the PAROTID GLAND
185
most common cause of post-op hypotension? how do you treat it?
anesthesia/analgesics on the myocardium if it was from narcotics -> Narcan if there is bradycardia -> atropine (anti-cholinergic)
186
vasovagal syncope is how do you manage?
a psychogenic rxn (caused by psychological factors), most common complication assoc. with local anesthetics - initial event is stress induced release of incr. catecholamines - signs resemble shock, early sign is PALLOR (pale) -put pt in supine position, legs elevated above heart (trendelenburg position), cool towel
187
most common cause of transient loss of consciousness in a dental office is
vasovagal syncope
188
3 drugs when given 1 hr before appt are safe to fearful patients
1. diazepam (valium) 2. promethazine (phergan) 3. pentobarbital (nembutal) or secobarbital (seconal)
189
hyperventilation in an anxious pt can lead to a __ spasm
carpodedal spasm (hand, thumbs, foot, toes)
190
a somatogenic reaction is
development of a rxn from an organic pathophysiologic cause
191
Shock symptoms include: the main factor in all types of shock is __ the 3 stages of shock are:
symp - tired, sleepy, confused, cold sweaty skin, BP drops main factor is reduced cardiac output! 1. compensatory stage - incr HR and peripheral resistance 2. progressive stage - metabolic acidosis 3. irreversible/refractory - organ damage
192
cardiogenic shock is most commonly caused by
myocardial infarction | -collapse from pump failure of the LEFT VENTRICLE
193
5 major types of shock
``` cardiogenic hypovolemic septic - from endotoxin from gram (-) bacteria neurogenic anaphylactic ```
194
the most abused drugs by dental professionals is
Meperidine (demerol) - narcotic analgesic to releive pain, cough suppressant - compares with MORPHINE
195
admin of meperidine and __ can cause life threatening hyperpyrexic rxns that can lead to seizures and coma
MAO-inhibitors
196
morphine causes
euphoria, analgesia, drwosiness, miosis, respiratory depression
197
2 tests that should be done before using a general anesthetic are
CBC | urinalysis (urine pH should be 6)
198
CBC includes 4 things
1. hematocrit - min is 30% for elective surgery 2. hemoglobin 3. total leukocytes (WBC) 4. total erythrocytes (RBC)
199
``` normal values for coagulation template bleeding time = __ min prothrombin time = __ sec partial thromboplastin time = __ sec platelets = __K/ml ```
1-9 min 11-16 sec 32-46 sec 140-440K
200
local contraindications to tooth extractions include
``` ANUG irradiated jaws malignant disease acute infection with uncontrolled cellulitis acute infectious stomatitis ```
201
systemic contraindications to tooth ext
- uncontrolled: diabetes mellitus, cardiac disease, dysrythmias, leukemias and lymphomas - debilitating diseases - severe bleeding disorders - pts on immunosuppressives, corticosteroids, cancer chemotherapeutic agents
202
conditions that require abx prophylaxis prior to OS
1. prosthetic heart valve 2. rheumatic valve disease 3. most congenital heart malformations NOT pacemakers cause endocardium isn't involved
203
standard prophylaxis for amoxicillin? clindamycin?
amox - 2 g | clinda - 600 mg
204
ideal time to remove impacted 3rd molars is when root is approx. how much formed?
2/3
205
complication most seen after ext of isolated max molare are
fracture of tuberosity or sinus floor
206
cavernous sinus thrombosis (CST) is usually caused by? usually occurs in what vein?
late complication of an infection (staph aureus) of the central face or paranasal sinuses OPHTHALMIC VEIN cause of absence of valves in angular, facial, ophthalmic veins
207
the most common neck space infection that involves the sublingual, submandibular, and submental spaces
Ludwig's Angina
208
submandibular space drains infxns from what teeth? where in relation to mylohyoid?
mand premolars and molars -> apices lie BELOW mylohyoid
209
sublingual space contains what gland
sublingual
210
submental space drains infections from what teeth? where in relation to mylohyoid?
medial part of submaxillary space | -drains from mand incisors and canines -> their apices lie ABOVE mylohyoid
211
most common site for supernumerary tooth is
maxillary incisor area, called a "mesiodens"
212
what Class lever is used for ext?
Class II | -teeth are ext by LUXATION perpendicular to long axis
213
luxation is
loosening of tooth by progressive severing of PDL fibers
214
what scalpel is used universally for all OS
#15
215
3 incisions used in OS
1. linear - for apicoectomies 2. releasing - do it at the LINE ANGLE 3. semi-lunar - for apicoetomies
216
suture sizing is based on 2 things
strength and diameter smallest diameter should be used ex. 9-0 has least strength and smallest diameter 3-0 and 4-0 are most common
217
most severe tissue rxn occurs with what kind of suture material?
plain catgut (resorbable - cause inflammatory rxn)
218
3 types of Resorbable sutures
1. plain gut - from sheep intestin, susceptible to rapid digestion 2. chromic gut - more resistant 3. polyglycolic acid - doesn't break down, more $
219
3 types of Non-Resorbable sutures
1. silk - multifilamentous, for INTRAORAL suturing 2. nylon - for FACIAL LACERATIONS 3. polypropylene - least likely to inflame should remove in 5-7 days
220
what is the Caldwell-Luc approach
opening made into max sinus via incision into canine fossa above level of premolar roots
221
teeth are resistant to crush but are not resistant to __
shear | -> place forcep beaks parallel to long axis
222
what is the primary direction for extracting: | max primary/deciduous molars? adult max molars?
max primary/decid -> PALATAL adult -> BUCCAL
223
genial tubercules are the attachment for what muscle?
suprahyoid - on lingual surface of mandible - NEVER excise cause if you did the tongue would be flaccid
224
dry socket is most common after ext what teeth
mandibular molars - usually 2-4 days after tooth ext - tx by flushing, place EUGENOL sedative dressing
225
pericoronitis assoc. with
crown of partially erupted tooth, most common with mand 3rd molar
226
5 phases of healing an extraction site
1. hemorrhage and blood clot 2. granulation tissue *GLUCOCORTICOIDS retard healing! 3. replacement of GT by CT and epithelialization 4. replacement of CT by fibrillar bone 5. recontour alveolar bone and bone maturation
227
3 stages of wound healing
1. inflammatory - vascular and cellular, neutrophils and lymphocytes predominate, macrophage is most important cell in healing! 2. proliferative (firbroblastic) - new collagen and blood vessels 3. maturation (remodeling)
228
what is the agent of choice to debride intraoral wounds?
3% H2O2
229
primary intention involves
both endosteal and periosteal proliferation | -little fibrous tissue is produced, with minor callus formation
230
secondary intention involves
mostly ENDOsteal proliferation | -lots fibrous tissue formed and callus is formed
231
greatest osteogenic potential occurs with what kind of graft?
autogenous cancellous graft and hemopoietic marrow
232
allogenic grafts (allografts or homografts)
SAME SPECIES most common is FREEZE-DRIED bone, or freeze-dried decalcified bone
233
autogenous grafts (autografts)
SAME INDIVIDUAL - most often used in OS - to restore large areas of lost mandibular bones after surgery or trauma
234
bone marrow for grafting is usually taken from
the ILIAC CREST (also used for ridge augmentation)
235
isogenic grafts (isografts or syngenesioplastic grafts)
SAME SPECIES, but GENETICALLY RELATED
236
xenogenic implants (xenografts or heterografts)
ANOTHER SPECIES not used in surgery
237
rejection of grafts is most common with these 2 types
ALLOgraft and XENOgraft
238
alloplastic graft
SYNTHETIC, tends to migrate from position where it was placed
239
hydroxyapatite is most commonly used for what procedure?
ridge augmentation - when placed in a subperiosteal environment, it bonds physically and chemically to bone - biocompatible, non-resorbable - cons: migration, poor ridge form, abnormal color, mental nerve neuropathy
240
high speed turbine drills are ok/not ok?
TOTALLY UNACCEPTABLE - tissue emphysema - septic cellulitis
241
2 techniques for frenectomy
1. simple excision and Z-plasty - when it's narrow | 2. V-Y plasty (localized vestibuloplasty) - good for lengthening, less scars
242
best way to enlarge prominence of chin is by
osteotomy - horizontal sliding
243
closed reduction is
closing the space btw a fractured bone without cutting through soft tissue or surrounding bone
244
systemic contraindications to elective surgery include
- blood dysplasias (hemophilia, leukemia) - uncontrolled diabetes mellitus - Addison's disease or any steroid deficiency - fever - nephritis - cardiac disease (usually not within 6 months of infarction)
245
most common indication for tooth transplantation is severe decay of what tooth? success is most predictable when roots are how much formed? most likely cause of failure is what? sequelae include?
1st molar (3rd molar placed) roots 1/3-1/2 formed with open apices failure with chronic, progressive EXTERNAL root resorption sequelae -> ankylosis and root resorption
246
contraindications to implant placement include
- diabetes - pituitary and adrenal insufficiency - hypothyroidism - tuberculosis - sarcoidosis - hx of uncontrolled bleeding
247
implants placed where have the highest failure rate?
maxillary anterior
248
3 types of bone-implant interface (integrations)
1. fibro-osseous integration - CT encapsulated implant within bone 2. osseointegration - most predictable long term stability, anchored into living bone 3. biointegration - hydroxyapatite or bioglass that bonds to bone
249
3 main groups of implants
1. endosseous - most common (80%), comes in 2 types - root-form: cylindrical, most common - blade-form (plate-form): when not enough bone 2. subperiosteal - below periosteum but above bone 3. transosseous - in atrophic mandible where root form could compromise strength of jaw
250
implant success requires
adequate transfer of force and biocompatibility histo - 35-90% bone contact, CT adhesion above bone clinically - no significant bone loss, no infxn, no mobility
251
4 types of biopsies
1. incisional - only part of lesion, a highly suspicious lesion 2. excisional - most often for oral lesions 3. needle - aspiration 4. exfoliative cytology - pap smear
252
what is the fixative used for routine biopsy?
10% formalin
253
biopsy indications
persists over 2 weeks, persistent hyperkeratotic changes, malignant characteristics, inflammatory lesion that doesn't respond to local tx in 2 weeks, persistent swelling
254
dentigerous cysts (primordial/follicular)
assoc. with crowns of unerupted tooth, result of degenerative changes in reduced enamel epithelium
255
eruption cysts
can incise or "deroof"
256
enucleation is
total removal of cystic lesion, used for congenital cysts, mucoceles, odontogenic cysts
257
marsupialization, decompression, partsch operation all create a __ in the wall of a cyst
surgical window, sac is opened and emptied
258
__ is the tx for ranulas, or a cyst large and close to vital structures
marsupialization
259
symptoms of dehydration
``` decr. BP weight loss incr. HR CO body temp sunkey eyeballs ```
260
secondary pulmonary hypertension is most often caused by what condition
COPD
261
COPD disorders (4)
1. bronchial asthma - dyspnea and wheezing 2. emphsema - often with chronic bronchitis 3. bronchiectasis - purulent sputum, hemoptysis 4. chronic bronchitis - excess mucus, productive cough, assoc. with smoking
262
common results of chronic bronchitis
cor pulmonale - enlarged heart right ventricle, airway narrowing, squamous metaplasia
263
atelectasis
collapse of part or all of a lung - most common anesthetic complication within first 24 hrs after general anesthesia - prolonged can lead to PNEUMONIA
264
pneumothorax is
presence of air in pleural cavity
265
__ and __ are the 2 most common causes of fever in a pt who had general anesthesia
pneumonitis (lung inflamed) | atelectasis
266
asthma is a syndrome with these 3 symptoms what drugs to avoid? how do you treat acute asthma attack?
dyspnea, cough, wheezing avoid: aspirin, NSAIDs, barbiturates, narcotics, erythromycin tx -> inhale selective beta 2 agonist (terbutaline, albuterol) -> if doesn't work then EPI
267
most severe clinical form of asthma is
status asthmaticus | -airway obstruction can lead to respiratory acidosis -> death
268
hemophelia is PTT is PT is bleeding time is
hereditary bleeding disorder, mostly males PTT is PROLONGED normal PT, BT
269
hemophelia __ and __ are sex linked recessive
A, B A - factor VIII deficiency B (christmas disease) - factor IX (plasma thromboplastin component) deficiency
270
hemophelia C (Rosenthal's syndrome) has a deficiency in
factor XI (plasma thromboplastin antecedent)
271
Von Willebrand's disease is inherited how?
autosomal dominant | -deficient in VWF (binding site for factor VIII, facilitates platelet adhesion to collagen for platelet plug)
272
most common cause of hemorrhagic disorders 3 ways this happens
thrombocytopenia, low platelets < 150K 1. decr. platelet production by bone marrow 2. incr. trapping of platelets by spleen 3. faster destruction of platelets
273
thrombocytopenia clinical features
purpuric lesions, nosebleeds, GI bleeding, urinary tract bleeding, severe hemorrhage
274
2 concerns when doing surgery on thrombocytopenia pts
post-op bleeding and | adrenal insufficiency
275
drugs that can potentiate bleeding after ext include
``` aspirin anti-coagulants broad-spec antibiotics alcohol anticancer drugs ```
276
best test to determine if OS can be safe on a pt taking coumadin
normal prothrombin time
277
this test detects coagulation defects of the intrinsic system, basic test for hemophilia
partial thromboplastin time (PTT) | normal is 25-36 sec
278
anti-coagulants include these drugs pts will most likely have prolonged __ and __ times
dicumarol, heparin, antithrombin III, enoxaparin, warfarin long PT and BT
279
__ and __ drugs inhibit platelet aggregation
apirin | NSAIDs
280
ecchymosis
hemorrhage into skin and subcutaneous tissue | -RBCs degrade, hemoglobin converted through bilirubin hemosiderin
281
most serious potential complication after ext on pt previously irradiated
osteoradionecrosis | -condition of non-vital bone
282
osteomyelitis is most often caused by what organism in kids what bones, in adults?
staphylococcus aureus -reduced blood supply predisposes bone to osteomyelitis kids -> long bones adults -> vertebrae, pelvis acute osteomyelitis more common in mandibule because blood supply better in max.
283
ABC of CPR
airway breathing - 12 breaths/min circulation - 15 compressions every 2 breaths
284
if CPR is effective, the pupils will __ if you did too much pressure then what organ may be injured? interrupting compressions can result in?
pupils CONSTRICT can damage LIVER less blood flow and BP drop to 0!
285
if normal BP cuff on obese pt, then reading will be low/high?
falsely HIGH
286
in congestive heart failure, what part of the heart fails first? common CHF signs
left ventricle signs - exertional dyspnea, paroxysmal nocturnal dyspnea (earliest and most common sign!), peripheral edema, cyanosis
287
what is given to manage pts with chest discomfort or possible MI?
nitroglycerin given sublingually
288
calcium levels are regulated by what hormone
parathyroid hormone | -if more PTH then bone resorption to increase calcium levels
289
low serum calcium will cause __ of nerves and muscles
hyperirritability
290
serum calcium is increased in these 4 conditions
1. hyperparathyroidism 2. chronic glomerulonephritis 3. hypervitaminosis D 4. multiple myeloma DEcreased in diabetes mellitus
291
phosphorus conc. is regulated by what hormone?
parathyroid hormone | -increase in hormone cause increase in phosphate excretion -> decrease in plasma phosphorus conc.
292
in health, ratio of calcium:phosphorus in blood is
10:4
293
blood glucose conc. is regulated by __ and __
insulin and glucagon
294
serum glucose is increased in these conditions: normal serum conc. of glucose is __ mg/dl
diabetes mellitus adrenal tumors incr. growth hormone liver dysfunction 70-120 mg/dl
295
glucocorticoid secretion is stimulated by __ which is produced in the __
by ACTH, produced in the anterior pituitary
296
__ secretes 20 mg of hydrocortisone daily
adrenal cortex
297
pts on lots of steroids repress production of __ it takes how long to regain full adrenal cortical fxn?
ACTH -> atrophy of adrenal cortex 1 yr
298
erythema multiforme is a hypersensitivity syndrome charactereized by: a severe form is called the __ syndrome
polymorphouse eruption, bullae and target "bulls eye shaped" lesions severe form -> Stevens-Johnson Syndrome
299
Cushin's syndrome is caused by? most common cause?
prolonged exposure of body's tissues to high levels of CORTISOL hormone most common cause is pituitary adenomas
300
metabolic alkalosis major effect on body is major causes? tx?
over-excitable nervous system, can cause tetany (tonic spasm) causes - diuretics, vomiting gastric acid, overactive adrenal gland (cushing's syndrome) tx -> ammonium chloride
301
respiratory alkalosis major cause? tx?
hyperventilation, liver cirrhosis, low oxygen in blood (high altitude), apirin overdose LESS COMMON than respiratory acidosis tx -> ammonium chloride
302
metabolic acidosis causes? tx?
CNS depressed, disorientation, comatosed -always during CPR major causes - chronic renal failure, diabetic ketoacidosis, lactic acidosis, poisons, diarrhea tx -> sodium bicarb
303
respiratory acidosis causes? tx?
buildup of CO2 in blood causes - hypoventilation, emphysesma, chronic bronchitis, severe pneumonia, pulmonary edema, astha tx -> sodium bicarb
304
most common pancreatic endocrine disorder and metabolic disease invooving glucose and lipids
diabetes
305
classic triad of diabetes is
polydipsia polyuria polyphagia
306
how to tx hypoglycemia in UNCONSCIOUS diabetic? CONSCIOUS diabetic?
unconscious -> IV injection of 50% dextrose in water conscious -> admin of oral carb (eat)
307
#1 cause of kidney disease, 40% of kidney failures is
diabetes | high BP is 2nd cause
308
end stage renal disease (SRD) is when there is? pts often taking what drugs?
permanent and almost complete loss of kidney function -pts often on steroid therapy, more tendency for infxn and bleeding
309
whn tx pts with renal insufficiency and pts on hemodialysis you should
avoid drugs metabolized or excreted by kidneys avoid NSAIDs (nephrotoxic) do OS day after dialysis
310
rheumatic fever is an acute inflammatory disease with systemic manifestations and involved with heart valves, which foollows what infection? how to tx?
group A beta-hemolytic streptococcus NOT an infection, this is an inflammatory RXN to an infection tx with penicillin
311
clinical dx of rheumatic fever when 2 criteria met. what are the major jones criteria? minor?
major jones - carditis, arthritis, chorea, erythema marginatum, subcutaneous nodules minor - fever, arthralgia, hx of rheumatic fever, EKG changes, lab tests
312
what valve is most commonly damaged from carditis resulting in rehumatic heart disease?
MITRAL (btw left atrium and left ventricle) the pulmonary is rarely involved