Orthopaedic surgery, antibacterial prophylaxis Flashcards
Q: What is the recommended antibacterial prophylaxis for joint replacement, including hip and knee surgery?
A: Single dose of i/v** cefuroxime** alone or i/v flucloxacillin + i/v gentamicin. Additional doses may be given for prolonged procedures or if there is major blood loss.
Q: When should intravenous antibacterial prophylaxis be administered for joint replacement surgery?
A: Up to 30 minutes before the procedure.
Q: When is a combination of i/v teicoplanin (or vancomycin) + i/v gentamicin recommended in joint replacement surgery?
A: If there’s a history of allergy to penicillins or cephalosporins or if there’s a high risk of meticillin-resistant Staphylococcus aureus.
Q: What is the recommended prophylaxis for closed fractures in orthopaedic surgery?
A: Single dose of i/v cefuroxime or i/v flucloxacillin. Additional doses may be given for prolonged procedures or if there is major blood loss.
Q: When should intravenous antibacterial prophylaxis be administered for closed fractures?
A: Up to 30 minutes before the procedure.
Q: When is a single dose of i/v teicoplanin (or vancomycin) recommended for closed fractures?
A: If there’s a history of allergy to penicillins or cephalosporins or if there’s a high risk of meticillin-resistant Staphylococcus aureus.
Q: What is the recommended prophylaxis for open fractures in orthopaedic surgery?
A: Use i/v co-amoxiclav alone or i/v cefuroxime + i/v metronidazole (or i/v clindamycin alone if there’s a history of allergy to penicillins or cephalosporins).
Q: When should prophylaxis for open fractures begin, and when should it continue until?
A: Start prophylaxis within 3 hours of injury and continue until soft tissue closure (maximum 72 hours).
Q: What should be used at the first debridement in open fractures?
A: A single dose of i/v cefuroxime + i/v metronidazole + i/v gentamicin or i/v co-amoxiclav + i/v gentamicin (or i/v clindamycin + i/v gentamicin if there’s a history of allergy to penicillins or cephalosporins).
Q: What is the recommended prophylaxis at the time of skeletal stabilization and definitive soft tissue closure in open fractures?
A: A single dose of i/v gentamicin + i/v teicoplanin (or vancomycin). Intravenous antibacterial prophylaxis should be given up to 30 minutes before the procedure.
Q: What is the recommended prophylaxis for high lower-limb amputation in orthopaedic surgery?
A: Use i/v co-amoxiclav alone or i/v cefuroxime + i/v metronidazole.
Q: How long should antibacterial prophylaxis be continued after a high lower-limb amputation procedure?
A: Continue for at least 2 doses after the procedure (maximum duration of prophylaxis is 5 days). If there’s a history of allergy to penicillin or cephalosporins, or if there’s a high risk of meticillin-resistant Staphylococcus aureus, use i/v teicoplanin (or vancomycin) + i/v gentamicin + i/v metronidazole.
Q: What alternative administration method for i/v metronidazole is suggested, and when should it be given?
A: It may alternatively be given by suppository, 2 hours before surgery, to allow for adequate absorption.
Q: What is the recommended antibacterial prophylaxis for joint replacement, including hip and knee surgery?
A: Single dose of i/v cefuroxime alone or i/v flucloxacillin + i/v gentamicin. Additional doses may be given for prolonged procedures or if there is major blood loss.
Q: When should intravenous antibacterial prophylaxis be administered for joint replacement surgery?
A: Up to 30 minutes before the procedure.
Q: When is a combination of i/v teicoplanin (or vancomycin) + i/v gentamicin recommended in joint replacement surgery?
A: If there’s a history of allergy to penicillins or cephalosporins or if there’s a high risk of meticillin-resistant Staphylococcus aureus.
Q: What is the recommended prophylaxis for closed fractures in orthopaedic surgery?
A: Single dose of i/v cefuroxime or i/v flucloxacillin. Additional doses may be given for prolonged procedures or if there is major blood loss.
Q: When should intravenous antibacterial prophylaxis be administered for closed fractures?
A: Up to 30 minutes before the procedure.
Q: When is a single dose of i/v teicoplanin (or vancomycin) recommended for closed fractures?
A: If there’s a history of allergy to penicillins or cephalosporins or if there’s a high risk of meticillin-resistant Staphylococcus aureus.
Q: What is the recommended prophylaxis for open fractures in orthopaedic surgery?
A: Use i/v co-amoxiclav alone or i/v cefuroxime + i/v metronidazole (or i/v clindamycin alone if there’s a history of allergy to penicillins or cephalosporins).
Q: When should prophylaxis for open fractures begin, and when should it continue until?
A: Start prophylaxis within 3 hours of injury and continue until soft tissue closure (maximum 72 hours).
Q: What should be used at the first debridement in open fractures?
A: A single dose of i/v cefuroxime + i/v metronidazole + i/v gentamicin or i/v co-amoxiclav + i/v gentamicin (or i/v clindamycin + i/v gentamicin if there’s a history of allergy to penicillins or cephalosporins).
Q: What is the recommended prophylaxis at the time of skeletal stabilization and definitive soft tissue closure in open fractures?
A: A single dose of i/v gentamicin + i/v teicoplanin (or vancomycin). Intravenous antibacterial prophylaxis should be given up to 30 minutes before the procedure.
Q: What is the recommended prophylaxis for high lower-limb amputation in orthopaedic surgery?
A: Use i/v co-amoxiclav alone or i/v cefuroxime + i/v metronidazole.
Q: How long should antibacterial prophylaxis be continued after a high lower-limb amputation procedure?
A: Continue for at least 2 doses after the procedure (maximum duration of prophylaxis is 5 days). If there’s a history of allergy to penicillin or cephalosporins, or if there’s a high risk of meticillin-resistant Staphylococcus aureus, use i/v teicoplanin (or vancomycin) + i/v gentamicin + i/v metronidazole.
Q: What alternative administration method for i/v metronidazole is suggested, and when should it be given?
A: It may alternatively be given by suppository, 2 hours before surgery, to allow for adequate absorption.
These flashcards can help you remember the key points for antibacterial prophylaxis in orthopaedic surgery.
it is GFC
not
KFC!!
prophylaxis as gentamicin,flucloxacillin and cefuraxime
