Orthopaedic surgery, antibacterial prophylaxis Flashcards

1
Q

Q: What is the recommended antibacterial prophylaxis for joint replacement, including hip and knee surgery?
A: Single dose of i/v** cefuroxime** alone or i/v flucloxacillin + i/v gentamicin. Additional doses may be given for prolonged procedures or if there is major blood loss.

Q: When should intravenous antibacterial prophylaxis be administered for joint replacement surgery?
A: Up to 30 minutes before the procedure.

Q: When is a combination of i/v teicoplanin (or vancomycin) + i/v gentamicin recommended in joint replacement surgery?
A: If there’s a history of allergy to penicillins or cephalosporins or if there’s a high risk of meticillin-resistant Staphylococcus aureus.

Q: What is the recommended prophylaxis for closed fractures in orthopaedic surgery?
A: Single dose of i/v cefuroxime or i/v flucloxacillin. Additional doses may be given for prolonged procedures or if there is major blood loss.

Q: When should intravenous antibacterial prophylaxis be administered for closed fractures?
A: Up to 30 minutes before the procedure.

Q: When is a single dose of i/v teicoplanin (or vancomycin) recommended for closed fractures?
A: If there’s a history of allergy to penicillins or cephalosporins or if there’s a high risk of meticillin-resistant Staphylococcus aureus.

Q: What is the recommended prophylaxis for open fractures in orthopaedic surgery?
A: Use i/v co-amoxiclav alone or i/v cefuroxime + i/v metronidazole (or i/v clindamycin alone if there’s a history of allergy to penicillins or cephalosporins).

Q: When should prophylaxis for open fractures begin, and when should it continue until?
A: Start prophylaxis within 3 hours of injury and continue until soft tissue closure (maximum 72 hours).

Q: What should be used at the first debridement in open fractures?
A: A single dose of i/v cefuroxime + i/v metronidazole + i/v gentamicin or i/v co-amoxiclav + i/v gentamicin (or i/v clindamycin + i/v gentamicin if there’s a history of allergy to penicillins or cephalosporins).

Q: What is the recommended prophylaxis at the time of skeletal stabilization and definitive soft tissue closure in open fractures?
A: A single dose of i/v gentamicin + i/v teicoplanin (or vancomycin). Intravenous antibacterial prophylaxis should be given up to 30 minutes before the procedure.

Q: What is the recommended prophylaxis for high lower-limb amputation in orthopaedic surgery?
A: Use i/v co-amoxiclav alone or i/v cefuroxime + i/v metronidazole.

Q: How long should antibacterial prophylaxis be continued after a high lower-limb amputation procedure?
A: Continue for at least 2 doses after the procedure (maximum duration of prophylaxis is 5 days). If there’s a history of allergy to penicillin or cephalosporins, or if there’s a high risk of meticillin-resistant Staphylococcus aureus, use i/v teicoplanin (or vancomycin) + i/v gentamicin + i/v metronidazole.

Q: What alternative administration method for i/v metronidazole is suggested, and when should it be given?
A: It may alternatively be given by suppository, 2 hours before surgery, to allow for adequate absorption.

A

Q: What is the recommended antibacterial prophylaxis for joint replacement, including hip and knee surgery?
A: Single dose of i/v cefuroxime alone or i/v flucloxacillin + i/v gentamicin. Additional doses may be given for prolonged procedures or if there is major blood loss.

Q: When should intravenous antibacterial prophylaxis be administered for joint replacement surgery?
A: Up to 30 minutes before the procedure.

Q: When is a combination of i/v teicoplanin (or vancomycin) + i/v gentamicin recommended in joint replacement surgery?
A: If there’s a history of allergy to penicillins or cephalosporins or if there’s a high risk of meticillin-resistant Staphylococcus aureus.

Q: What is the recommended prophylaxis for closed fractures in orthopaedic surgery?
A: Single dose of i/v cefuroxime or i/v flucloxacillin. Additional doses may be given for prolonged procedures or if there is major blood loss.

Q: When should intravenous antibacterial prophylaxis be administered for closed fractures?
A: Up to 30 minutes before the procedure.

Q: When is a single dose of i/v teicoplanin (or vancomycin) recommended for closed fractures?
A: If there’s a history of allergy to penicillins or cephalosporins or if there’s a high risk of meticillin-resistant Staphylococcus aureus.

Q: What is the recommended prophylaxis for open fractures in orthopaedic surgery?
A: Use i/v co-amoxiclav alone or i/v cefuroxime + i/v metronidazole (or i/v clindamycin alone if there’s a history of allergy to penicillins or cephalosporins).

Q: When should prophylaxis for open fractures begin, and when should it continue until?
A: Start prophylaxis within 3 hours of injury and continue until soft tissue closure (maximum 72 hours).

Q: What should be used at the first debridement in open fractures?
A: A single dose of i/v cefuroxime + i/v metronidazole + i/v gentamicin or i/v co-amoxiclav + i/v gentamicin (or i/v clindamycin + i/v gentamicin if there’s a history of allergy to penicillins or cephalosporins).

Q: What is the recommended prophylaxis at the time of skeletal stabilization and definitive soft tissue closure in open fractures?
A: A single dose of i/v gentamicin + i/v teicoplanin (or vancomycin). Intravenous antibacterial prophylaxis should be given up to 30 minutes before the procedure.

Q: What is the recommended prophylaxis for high lower-limb amputation in orthopaedic surgery?
A: Use i/v co-amoxiclav alone or i/v cefuroxime + i/v metronidazole.

Q: How long should antibacterial prophylaxis be continued after a high lower-limb amputation procedure?
A: Continue for at least 2 doses after the procedure (maximum duration of prophylaxis is 5 days). If there’s a history of allergy to penicillin or cephalosporins, or if there’s a high risk of meticillin-resistant Staphylococcus aureus, use i/v teicoplanin (or vancomycin) + i/v gentamicin + i/v metronidazole.

Q: What alternative administration method for i/v metronidazole is suggested, and when should it be given?
A: It may alternatively be given by suppository, 2 hours before surgery, to allow for adequate absorption.

These flashcards can help you remember the key points for antibacterial prophylaxis in orthopaedic surgery.

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it is GFC
not
KFC!!

A

prophylaxis as gentamicin,flucloxacillin and cefuraxime

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