Flashcards in OSCE Study Book Questions Deck (21):
Which of the following is a RF for rapid cycling mania?
1. Hyperthyroidism 2. Bipolar II Disorder 3. Male gender 4. Depressive episode at onset 5. Shorter duration of illness
Bipolar II Disorder. Rapid cycling is a specifier of the longitudinal course of bipolar I or II Disorders.
What is defined as 4 mood episodes within 12 months that meet the criteria for a manic, Hypomania, or major depressive episode. Episodes are demarcated by partial or full remission for at least 2 month or by a switch to an episode of opposite polarity. RF include; female gender, bipolar II subtype, longer duration of illness, family Hx of mood disorders, clinical or sub clinical hypothyroidism, poor response to lithium, use of antidepressants
Rapid cycling mania specifier
Which of the following statements is true about buspirone?
1. It is a partial 5HT antagonist 2. It brings with high affinity to benzodiazepine receptors 3. It has anticonvulsant properties 3. It does not cause sedation in the elderly
Does not cause sedation in the elderly.
Buspirone hydrochloride is an anxiolytics. What receptors does it act on and what receptor does it not bind to?
Binds to 5HT and does not bind to GABA.
What are the major SE of Buspirone?
HA, nausea, dizziness, and tension.
What are the rare SE of buspirone?
Tachycardia, palpitations, CP, drowsiness, confusion, and seizures
Which of the following is not associated with ECT?
1. Arrhythmia 2. BP changes 3. ECG changes 4. Permanent neuro deficits 5. Prolonged seizures
Which of the following is true about mono amine oxidase inhibitors (MAOIs)? 1. The antidepressant activity of MAOIs is directed toward mono amine oxidase B inhibition 2. Mono amine oxidase A specifically binds to serotonin
Mono amine oxidase A specifically binds to serotonin.
MAOIs differ from each other in enzyme activity. There are 2 subtypes of MAO enzymes; A and B. MAOa binds to 5HT/NE and MAOb binds to phenylethylamine.
Which of the following statements is true about GABA receptors? 1. They are predominant excitatory receptors in the CNS 2. GABAb receptors are G protein - coupled receptors.
GABAb receptors are G protein coupled receptors
GABA is the major ______ (inhibitory/excitatory) NT in the CNS
BZDs exert their action by potentiating the activity of _______ receptors
BZD binding increases the frequency of opening of the ______ ______ complexed with the _____ receptor.
Chloride Channel. GABAa.
BZD increases the frequency of opening of the chloride channel complexed with the GABAa receptor.
GABAb receptors increase ______ levels via G protein coupling
GABAb receptors increase potassium levels via G protein coupling
GABAc receptors are direct coupled receptors with ligand gated ______ ____ channels
GABAc receptors are direct coupled receptors with ligand gated chloride ion channels.
Methadone is a ______ (full/partial) opiate agonist
Methadone is a full opiate agonist
Buprenorphine is a _______ (full/partial) opiate agonist
Buprenorphine is a partial opiate agonist.
Does naloxone or naltrexone have a longer duration of action?
Which of the following is not a temperamental variable as define by Alexander Thomas? 1. Activity level 2. Distract ability 3. Low adaptability 4. Intensity of reaction 5. Regularity
Low adaptability is not a temperamental variable
What are the nine temperamental variables?
Activity level, persistence, distractibility, initial reaction, adaptability, mood, intensity of reaction, sensitivity or sensory threshold, regularity or rhythmicity
Is absent tendon reflexes a feature of normal sleep?