Flashcards in Osteoarthritis/DJD Deck (13)
Most common form of arthritis worldwide
[also leading cause of pain and disability of lower extremity]
Risk factors for OA
OA is characteristically non-inflammatory and without systemic symptoms. The pain is _____ by rest, morning stiffness is brief, and it is oligoarticular
Pathophysiology of RA involves a combination of multifactorial stressors including the consequences of aging, _______ articular cartilage loss (type II), increasing thickness and _____ of subchondral bone plate, outgrowth of ______ at the joint margin, joint injury, and extracellular matrix degeneration.
Weakness of muscles bridging the joint may also play a role
Clinical manifestations of OA
Usually weight bearing and frequently used joints
Usually >50 y/o
Insidious onset of intermittent sxs, becomes more persistent and severe over time
Pain worse with activity, relieved by rest
Crepitus, decreased ROM, effusion (cool, not hot)
Heberdens and bouchard nodes
Hip involvement manifests as groin pain
Spondylosis and spinal stenosis
What are some potential findings on radiographs of OA?
Asymmetric joint space narrowing
Osteophytes and marginal lipping
Joint mice (loose particles)
Primary OA is the most common type, no identifiable cause is recognized.
What are the most common joints affected in this type?
1st carpometacarpal joint
Hip and knee
Type of osteoarthritis that affects DIP and PIP joints but is more painful than typical hand OA; more common in women and shows central erosions on radiographs with “seagull” apearance in finger joints
Erosive OA (inflammatory OA)
[note that central erosions are erosive OA, while marginal erosions would indicate RA]
Secondary causes of OA
Surgical repair (ACL, meniscus, etc)
What joints are typically affected in OA secondary to hemochromatosis?
2nd/3rd MCP joints
What joints are typically affected in OA secondary to pseudogout?
What joints are typically affected in OA secondary to hyperparathyroidism?