Other

Question 1

Order of strength of bonding within and between molecules in solution

stongest to weakest

Answer 1

Covalent > ion-dipole > H-bonding > van der waals

Question 2

how do you calculate isoelectric points of a structure?

Answer 2

add all the pKa values together and divide by the number of vales (similar to finding a mean average).

Question 3

define lipids

Answer 3

• Lipids are a group of naturally occurring, significantly hydrophobic, molecules
• fats, waxes, sterols, fat-soluble vitamins (such as vitamins A, D, E,
  and K)
• monoglycerides, diglycerides, triglycerides and phospholipids.

Question 4

drug discovery

Answer 4

It is the process which ascertains the effectiveness and safety of potential
drug candidates.

Question 5

what dies allosteric inhibition of an enzyme involve?

Answer 5

Inhibition of the enzyme through the binding of an allosteric inhibitor outside
of the enzymes’ active site.

Question 6

What is a partial agonist?

Answer 6

Molecules that have an agonistic effect on the receptor, but only ever
achieve a submaximal response.

Question 7

What are the protein structures called that are expressed within the cell
membranes and interact with endogenous signalling molecules or some drugs
to initiate an intracellular response?

Answer 7

Receptors

Question 8

What primary intermolecular force determines alpha helix, beta sheets and parallel beta sheets confirmation?

Answer 8

Hydrogen bonding
* alpha helix - between carbonyl oxygen and amide hydrogen of the peptide backbone.
* beta sheets - between backbone carbonyl and amino groups
* parallel beta sheets - between carbonyl oxygen of one amino acid and the amide hydrogen of aother, running in the same direction.

Question 9

why are DNA sequences written in triads (groups of three letters)?

Answer 9

to show the seperate codons. three nucleotides (letters) represents a codon, which represents an individual amino acid.