Other antimicrobials and their clinical indications Flashcards Preview

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Flashcards in Other antimicrobials and their clinical indications Deck (27):
1

Amphotericin B IV

Aspergillus and cryptococcal meningitis.
Not first line for candida
Ampho-terrible side effects

2

Nystatin

Oropharyngeal and vaginal candidiasis
Topical only

3

Fluconazole IV/PO

Invasive C. albicans, esophageal canddiasis
Not for non-alibicans Candida

4

Itraconazole PO

Oral stepdown fro coccidiomycosis, blastomycosis, histoplasmosis

5

Voriconazole IV/PO

reserve for aspergillus, fusarium, or drug resistant fungal infections

Broad spectrum

6

Posaconazole PO

Broadest spectrum azole, reserve for fusarium or other hard cases

7

Anidulafungin IV

serious non-albicans Candida infection

8

Caspofungin IV

serious non-albicans Candida infection

9

Micafungin IV

serious non-albicans Candida infection

10

Terbinafine

tinea capitis, onychomycosis, tinea pedis, tinea cruris, tinea corporis, tinea versicolor

Can be topical or PO

11

Clotrimazole

cream for tinea and cutaneous candidiasis

12

Ciclopirox

nail lacquer for mild onychomycosis, cream for tinea

13

Tolnaftate

tinea cream, powder, solution, spray

14

Chloroquine

All 5 plasmodium species, but resistance developing. Prophylaxis or treatment

15

Mefloquine

P. falciparum, P. vivax prophylaxis

16

Atovaquone/proguanil

P. falciparum prophylaxis and treatment

17

Artesunate

P. falciparum treatment for severe malaria

18

Quinine

P. falciparum, P. vivax, 2nd line treatment for severe malaria

19

Primaquine

P. ovale, P. vivax prophylaxis

20

Albendazole

strongyloides, roundworm, pinworm, whipworm, hookworm

21

Mebendazole

roundworm, pinworm, whipworm, hookworm (NOT strongyloides)

22

Ivermectin

mainstay is strongyloidiasis

23

Pyrantel pamoate

pinworm, hookworm

24

Praziquantel

intestinal tapeworms

25

Iodoquinol

Dientameoba fragilis, amebiasis

26

Paromomycin

alternative for Dientamoeba, amebiasis

27

Permethrin

scabies, lice
available in a creme rinse, lotion