Overdose and Poisoning Flashcards Preview

(finals) Treatment algorithms > Overdose and Poisoning > Flashcards

Flashcards in Overdose and Poisoning Deck (8)
Loading flashcards...
1

Paracetamol Overdose

1. Establish timing and dosing of overdose to assign treatment group

(if 150MG/kg within 1hr = Activated charcoal and immediate treatment )
(if staggered overdose = immediate treatment)
(if 1-4hrs after ingestion, take bloods at 4hrs and compare to nomogram)
(if >4-8hrs take bloods immediately and compare to nomogram)
(if 8-24 hrs take bloods immediately and treat whilst waiting for result)

2. NAC (N-Acetylcystine/ Parvolex) in 3 infusions
1. 150mg/kg over 1 hr
2. 50mg/kg over 4hrs
3. 100mg/kg over 16hours

3. Have chlorphenamine ready in case of rash (common SE) only stop infusion in anaphylaxis- methionine alternative.

4. keep an eye on hypoglycemia

2

Salicylate (asprin) poisoning

1. Correct dehydration
2. Heart monitor
3. Activated charcoal if early
4. Blood and Urine monitoring-
5. Correct acidosis with
-Sodium Bicarbinate
-Dialysis

3

Opioid Overdose

NALOXONE
(IM first if risk of absconding)
0.4-2mg IV, repeat every 2 mins until breathing restored.
Atropine to ease withdawral
Sedation
Methadone for frequent users

4

Warfarin

Vitamin K

5

CO

High flow 100% O2
Mannitol is severe
Hyperbaric O2 in specalist centre

6

Cyanide

Sodium nitrate / Sodium Thiosulphate

7

Alcohol Poisoning

If ingested within 1hr NG aspiration and gastric lavage

Supportive Care:
-Temp*
-BM*
-Fluids*
-also track HR, BP and GCS (be ready to intubate)
- other bloods U&E, V/ABG, Blood Alcohol,
-ECG
-CT head

8

Neuroleptic Malignant Syndrome following anti-psychotics

Discontinue drug
DANTROLENE IV
Supportive measures
-cooling
-intubate / ventilate
-IVI
-Dialysis
Measure response in CK, Urinary myoglobin, U&E, ABG, FBC, and coagulation and support for at least 7/7