Overview of Antibody-Mediated Immunity

Question 1

Describe the characteristics of mature B cells and the roles of the major subsets of mature B cells in antibody-mediated immunity.

Answer 1

x

Question 2

Describe the general features and results of signaling through the B cell antigen receptor, including co-receptor signaling.

Answer 2

x

Question 3

Describe the presentation of protein antigens by B cells to helper T cells, the key components of T cell help and the results of T cell help for B cells, including germinal centers.

Answer 3

x

Question 4

Explain the general process and significance of immunoglobulin heavy chain isotype switching, somatic hypermutation of immunoglobulin genes and affinity maturation of antibody responses.

Answer 4

x

Question 5

Compare and contrast the characteristics and functions of plasma cells and memory B cells.

Answer 5

x

Question 6

Compare and contrast antibody responses to T cell-dependent and T cell-independent antigens.

Answer 6

x

Question 7

Compare and contrast the characteristics and effector functions of the different antibody isotypes.

Answer 7

x

Question 8

Explain the functions of the neonatal Fc receptor and the role of maternal IgG in neonatal immunity.

Answer 8

x