Oxygen Flashcards

1
Q

How does CFTR gene alteration lead cause symptoms of CF

A

Must maintain a balance of water and, Na+, Cl+ so mucus is thin enough to move out of the lungs and removed bacteria and virus trapped in it
Chloride channel cannot open - not enough Cl- are removed - mucus becomes too thick, cannot be clear, bacteria and virus grows.

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2
Q

Purpose of low flow nasal cannula and how much O2 they deliver

A

Low flow nasal cannula/prongs 1L - 4L from 24%-36% O2

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3
Q

examples of inhaled corticosteroids

A

Becotide, Clenil, QVAR

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4
Q

examples of oral corticosteroids

A

. prednisolone, hydrocortisone

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5
Q

Purpose of low flow mask and how much O2 they deliver

A

deliver more oxygen than nasal cannula 6-8L/min 40-50%O2

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6
Q

Purpose of high flow mask and how much O2 they deliver

A

up to 15L/min OR 60% O2 high oxygen demand, Venturi valves for more accuracy

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7
Q

Purpose of reservoir mask and how much O2 they deliver

A

purpose of bag attached to reservoir mask. Contains 1L reservoir helps to increase the inspired oxygen concentration by preventing oxygen loss during inspiration. Because of the valve (non rebreathing) it prevents CO2 from building up so 55-90% O2 is delivered at 6-15L/min. if no valve is present (Partial rebreathing) 35-60% 6-15L/min.

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8
Q

function of mMRAC scale for reviewing COPD

A

shows how easy they get breathless throughout the day. e.g. I only get breathless w/ strenuous exercise = grade 0

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9
Q

function of CAT scale for reviewing COPD

A

how often they cough, do they have mucus, chest tightness etc

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10
Q

Describe haldane effect

A

oxygenated blood - haemoglobin has a high affinity to pick up O2
deoxygenated blood - haemoglobin has affinity to pick up CO2

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11
Q

describe hypoxic theory

A

normal - high levels of CO2 drive inspirationÂ
hypercapnic patients - chronic elevated levels of CO2 (chemoreceptors desensitised) therefore decreased O2 drives respiration

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