Flashcards in P4 +5 - Disorders of growth and neoplasia 2/3 Deck (74)
What are the 2 classifications of tumours?
what are the 2 behaviours of tumours?
Benign v Malignant
what is the growth patten of benign tumours?
Expand and Remain localised
what is the growth rate of benign tumours?
what are the clinical effects of benign tumours?
local pressure effects: hormone secretion
what is the treatment for benign tumours?
what is the histology of benign tumours?
Resembles tissue of origin
what is the nuclei of benign tumours?
small, regular, uniform
what are the mitoses of benign tumours?
what is the growth patten of malignant tumours?
Infiltrate locally, metastasize (spread to distant sites)
what is the growth rate of malignant tumours?
what is the clinical effects of malignant tumours?
Local pressure and destruction,
Inappropriate hormone secretion
what is the treatment for malignant tumours?
Excision and additional therapy if metastases
what is the histology of malignant tumours?
Variable, many differ from tissue of origin
what is the nuclei of malignant tumours?
what are the mitoses of malignant tumours?
Numerous, including abnormal forms
How can tumours be further classified?
-the cell type they resemble, ie their differentiation
-Most tumours resemble to some extent the tissue from which they arise
what is the benign tumour of covering epithelia?
what is the malignant tumour of covering epithelia?
what is the benign tumour of Glandular epithelia?
what is the malignant tumour of glandular epithelia?
What are the benign tumours of smooth muscle, skeletal. muscle, bone forming, cartilage fibrous, blood vessels , adipose?
What are the malignant tumours of smooth muscle, skeletal. muscle, bone forming, cartilage fibrous, blood vessels , adipose?
what may some highly malignant tumours be?
undifferentiated ie do not show any definite form of differentiation
Why does tumour type matter?
-Different tumour types behave in different ways
-Different benign tumours can behave differently
-Not all malignant tumours are equally malignant
What is the prognosis?
-Prediction of the probable course and outcome of disease
-Appropriate treatment and estimate survival
What does cancer prognosis include?
-Tumour Grade (Histology)
-Tumour Stage (Histology, Clinical, Radiological)
-Other Parameters (Patient ,Tumour)
What does knowing patterns of spread of tumour types aid?
diagnosis, staging and treatment
what is important anatomical knowledge to know for tumours?
Sentinal lymph node biopsy