p53 protein

Question 1

what role does p53 have?

Answer 1

it is a tumor supressor

Question 2

What does p53 activate and for what?

Answer 2

activates other proteins to repair damaged DNA

Question 3

what can p53 also activate?

Answer 3

apoptosis

Question 4

what is apoptosis

Answer 4

programmed death of cells if damaged cannot be repaired

Question 5

What is oncogene

Answer 5

a gene that can transform a cell into a tumor cell (in certain circumstances)

Question 6

what does it mean to have a mutated p53 protein

Answer 6

it means the p53 protein is not functioning so when a error/tumor is detected, it wont make the undergo cell-suicide or be able to repair it so it allows tumor cell to keep dividing

Question 7

1st mutation/loss? result?

what kind of gene is activated

Answer 7

1 out of the 2 p53 gene is not working
susceptible to cancer

Oncogene is activated

Question 8

2nd mutation/loss?

what does it lead to

Answer 8

2 out of 2 p53 gene is not working so it will lead to cancer

Question 9

What is the working p53 protein’s process? : aptosis

Answer 9

Bad shit is detected –> p53 attacks bad cell –> cell suicide

Question 10

What is the working p53 protein’s process?: non aptosis

Answer 10

bad shit is detected –> cell cycle arrest –> DNA repair –> cell cycle restart

Question 11

What is nonfunction p53 protein process?

Answer 11

bad shit is detected –> p53 isn’t functioning –. uncontrolled cell division due to cell cycle continuing