PACES revision Flashcards
GI history?
Blood/mucus in stool
Abdo pain
Diarrhoea/constipation
Bloating
Frequency of passing stools
Dark urine/pale stools
Ask about previous surgeries
FLAWS
Diverticulitis presentation
acute left iliac fossa pain +/- diarrhoea and fever
Peptic ulcer disease presentation
chronic epigastric pain +/- reflux symptoms
Important to remember?
ICE!!!
MSK history?
Pattern of joint involvement
Any history of trauma?
Fever, skin rash, weight loss, eye signs, bowel symptoms, scalp tenderness, red eyes, chest pain
Pain, swelling, stiffness, muscle pain, deformity
FLAWS
ICE
Cardiac histories?
Chest pain - SOCRATES
SOB
Swelling, orthopnoea, pink frothy sputum
Palpitations
Dizziness, syncope, claudication
Cardiac RF?
Hypertension (high blood pressure)
Hypercholesterolaemia (high cholesterol)
Family history (heart attack < 60 years old in biological relative)
Smoking
Diabetes
Resp history?
SOB
Wheeze
Cough +- productive
chest pain
Sputum
Haemoptysis
FLAWS
Smoking, pets, occupation, allergens
Recent travel
ICE
Differentiating COPD and asthma?
foot drop and a peripheral neuropathy
CMT, GBS, CIDP, diabetes, alcohol, B12 deficiency,
Side effects of cushing’s syndrome?
Osteoporosis, dyslipidaemia, HTN, T2DM
Causes of Cushing’s
C – Cushing’s disease (a pituitary adenoma releasing excessive ACTH)
A – Adrenal adenoma (an adrenal tumour secreting excess cortisol)
P – Paraneoplastic syndrome
E – Exogenous steroids (patients taking long-term corticosteroids)
Ix for cushing’s
Low dose dexamethasone suppression test
High dose dexamethasone suppression test
24-hour urinary free cortisol
Full blood count may show a high white blood cell count
U&Es may show low potassium if an adrenal adenoma is also secreting aldosterone
MRI brain for a pituitary adenoma
CT chest for small cell lung cancer
CT abdomen for adrenal tumours
Nelson’s syndrome
Involves the development of an ACTH-producing pituitary tumour after the surgical removal of both adrenal glands due to a lack of cortisol and negative feedback. It causes skin pigmentation (high ACTH), bitemporal hemianopia and a lack of other pituitary hormones.
Diagnosing addison’s disease
Short synacthen test
Secondary adrenal insufficiency?
caused by a reduction in adrenocorticotropic hormone release. May be seen as part of panhypopituitarism, an isolated deficiency, following brain injury or secondary to medications.
Tertiary adrenal insufficiency
caused by a reduction in corticotropin-releasing hormone, most commonly seen following chronic glucocorticoid steroid use.
Causes of acromegaly?
Pituitary adenoma
DI treatment?
desmopressin
Fluid restrict
Prolactinoma sx?
Visual field problems, headaches, lethargy, galactorrhoea, hair growth, decreased libido, gynaecomastia, infertility, irregular menstruation, painful breasts, impotence
Treatment of prolactinoma?
1st line = Bromocriptine/cabergoline
2nd line = transphenoidal surgery
SIADH?
Body weakness
Fatigue, dizziness, confusion, lethargy
Muscle cramps
Seizures
Ix: Urine analysis, hyponatraemia, low plasma osmolarity
Tx: Water restriction
splenomegaly and keloid scars
Sickle cell disease
Hypogonadotrophic hypogonadism
(low LH and FSH resulting in low testosterone), can be due to:
Pathology of the pituitary gland or hypothalamus
Suppression due to stress, chronic conditions or hyperprolactinaemia
Kallman syndrome
Steroid use