Paediatric Cancer

Question 0

Philadelphia chromosome can cause which cancer?

Answer 0

Leukaemia

Question 1

What’re the common paediatric cancers?

Answer 1

Leukaemia, CNS tumours, Lymphoma

Question 2

Many childhood cancers are derived from what cells?

Answer 2

Blast cells which are immature

Question 3

Wilms tumour

Answer 3

?

Question 4

Acute lymphoblastic leukaemia

Answer 4

Commonest malignancy in children. Peak age at 4. Pancytopenia

Question 5

What is seen on a blood film in leukaemia ?

Answer 5

Blast cells

Question 6

What’s the history of leukaemia in children?

Answer 6

Bone pain, weight loss

Question 7

Cushingoid appearance during leukaemia is due to?

Answer 7

Steroids

Question 8

Wilms tumour

Answer 8

Nephroblastoma. Peaks at 2-3 years. Typical metastasises to the lung. Associated with some congenital abnormalities

Question 9

Neuroblastoma

Answer 9

Arises from neural crest cells - sympathetic ganglion

Question 10

Presenting features of posterior fossit tumour

Answer 10

Early morning waking, N&V, impaired vision (papal oedema)

Question 11

Bone tumours are most likely to effect which age group?

Answer 11

Teenagers

Question 12

Down’s syndrome increases the risk of developing which cancer?

Answer 12

Leukaemia