MOCK QUESTIONS 201

Question 1

What is the first-line statin for a 77-year-old man diagnosed with unstable angina?

Answer 1

Atorvastatin 80mg (Because he’s agina, heart failure, NSTEMI/STEMI)

Question 2

What is the mechanism of action of rifampicin?

Answer 2

Inhibits transcription of bacterial genes by targeting bacterial RNA polymerase.

Question 3

Which drug is used to manage symptoms of acute episodes of angina?

Answer 3

A: Glyceryl trinitrate 400 microgram/dose sublingual spray.

Question 4

What is the treatment for a 24-year-old male with cloudy penile discharge diagnosed with chlamydia?

Answer 4

Doxycycline 100 mg twice daily for 7 days.

Question 5

What is the treatment for a 26-year-old female presenting with a chancre lesion, diagnosed with syphilis?

Answer 5

Benzylpenicillin 2.4 million units intramuscular injection.

Question 6

What structure prevents food from entering trachea ?

Answer 6

Epliglottis

Question 7

Which layer of alimentary canal has role in mucous secretion ?

Answer 7

Mucosa

Question 8

What organs secretes enzyme amylase ?

Answer 8

Salivatry glands

Question 9

Which cell produces Pro enzyme pepsinogen

Answer 9

Chief cell

Question 10

What cell produces intrinsic factor ?

Answer 10

Parietal cell

Question 11

Which cell produces HCL apart from Parietal cells ?

Answer 11

G (gGastric )cells

Question 12

Which vitamin does intrinsic factors help absorb ?

Answer 12

B12. Causes production of RBC

Question 13

Pepsin breaks down which food type ?

Answer 13

Protein

Question 14

Is food entering the stomach a drjver of the cephalic (1st phase )

Answer 14

NO

Question 15

Treatment for Cystic fibrosis ?

Answer 15

Dornase alfa

Question 16

Function of pancreas

Answer 16

Produces/secretes digestive enzymes
Produce insulin

Question 17

Function of liver

Answer 17

Makes bile
Removal of waste products
to make clotting factors ?

Question 18

follow digestion what state protien enters blood stream ?

Answer 18

amino acids

Question 19

Longest segment of alimentary canal ?

Answer 19

ileum

Question 20

Term to describe mixing movments that occur to chyme ?

Answer 20

Segmentation

Question 21

How do ppi’s work ?

Answer 21

Block H+/k+ ATPase pump. Results in reduction in H+ ions being pumped into stomach

Question 22

If bile ducts are damaged, What nutrient will be hardest to digest ?

Answer 22

Fats

Question 23

Where is Vitamin B12 absorbed

Answer 23

ileum (small intestine )

Question 24

List main features of GORD ? + red flag ?

Answer 24

Acid from stomach leaks up into oesophagus causing…

Heartburn
acid reflux
vomiting

Red flag = unexplained weight loss + Dysphagia (diff swallowing)

Question 25

How is GORD, peptic ulcers, H pylori diagnosed ?

Answer 25

Full drug history for all GORD = Endoscopy Urea breath test = H pylori infeection

Question 26

What a sentry drug ? give example

Answer 26

Antibiotics combined with another agent which allows drug to overcome bactieral resistance. Clavulanic acid sentry drug. It is combined with amoxicillin in co-amoxiclav to inhibit beta-lactamase enzymes

Question 27

What do Quinolones inhibit

Answer 27

DNA gyase

Question 28

What condition is

Question 29

What is a common resistance mechanism invlving enzyme production ?

Answer 29

Beta lactames

Question 30

Treatment for Herpes

Answer 30

Acyclovir

Question 31

What do beta lactams do ?

Answer 31

Inhibit cell wall synthesis (Penecillin)

Question 32

What do quinoloes do ?

Answer 32

Inhibit DNA gyrase

Question 33

Main treatment for Complicated UTI's ?

Answer 33

Ciproflaxcin

Question 34

Type of drug that inhibits viral entry ?

Answer 34

Entry inhibitors (Maraviroc)

Question 35

Type of drug that inhibits viral fusion

Answer 35

Viral inhibitors (Enfurviritide)

Question 36

Drug for complication UTI ?

Answer 36

1g Ciprofloxacin

Question 37

What is common resistance mechanism involving enzyme production ?

Answer 37

Beta lactamases

Question 38

MOA for macrolides ?

Answer 38

Inhibit Protein synthesis by targeting 50s ribosomal subunits

Question 39

MOA for Quinoloes ?

Answer 39

Inhibit bactieral DNA replication by targeting DNA gyrase

Question 40

MOA for beta lactames ?

Answer 40

Inhibit cell wall synthesis

Question 41

MOA for tetracyclines ?

Answer 41

Inhibit protein synthesis by targeting 30s ribosmal subunits