Substance misuse

Question 1

MOA of stimulant drugs + example ?

Answer 1

Increases Dopamine released into synaptic cleft (Amphetamines)

Question 2

MOA of Depressants + example ?

Answer 2

Increases GABA (Calming/anti-anxious neurotransmitter) . Results in LESS brain activity (Diazepam)

Question 3

Sings of drug misuse (Classified by ICD-10)

Answer 3

Withdrawl symptoms
Strong desire to use
Tolerance to drug
Continued use despite harm
(Need MORE than 3)

Question 4

Complications of Drug Misuse ?

Answer 4

Medical - Infection (HIV), kidney/liver damage
Psychiatric - Psychosis, withdrawl symptoms

Question 5

Common samples used in drug testing ?

Answer 5

Urine
Saliva
Hair

Question 6

drugs used for opiate withdrawal symptom relief?

Answer 6

Pain - Paracetamol/NSAIDS
Diarrohea - Loperamide
Anxiety - Diazepam

Question 7

Substitution medication for Opioid dependence ?

Answer 7

Methadone

Question 8

What is naloxone used for ?

Answer 8

IMMEDIATE reversal of opioid dependance

Question 9

What is naltrexone used for in addiction ?

Answer 9

LONG TERM opioid antagonist
Prevents relapse (cravings) by binding to opioid receptors WITHOUT activating them
Requires Liver function test

Question 10

UK alcohol consumption guidelines?

Answer 10

14 units alcohol / 140g

Question 11

What is FASD ?

Answer 11

Fetal Alcohol spectrum disorder. INCLUDES
Growth problems
Facial abnormalities
CNS damage

Question 12

medications for alcohol dependence treatment. ?

Answer 12

Disulfiram: makes alcohol aversive
Acamrpoaste : Reduces glutamate
Baclofen : GABA B agonist reduces craving