pain Flashcards
1
Q
naturally occurring opioids
A
morphine and codeine
2
Q
semisynthetic occur opioids
A
analogs of morphine -
heroin and dihydromorphone
higher risk for PONV ?
3
Q
synthetic opioids:
A
exogenous 4 groups morphinan derivatives diphenyl derivatives benzomorphans phenylpiperdines
4
Q
morphinan derivatives
A
levorphanol, butorphanol
5
Q
diphenyl derivatives
A
methadone, prolonged QT
6
Q
benzomorphans
A
phenzocaine, pentazocine,
7
Q
CYP2D6 alters
A
5 common mutations of CYP2D6 alter metabolism of CODIENE oxycodone hydrocodone methadone
Unpredictable, pharmacokinetics and half lives
