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Pharm 1 > Pain, inflammation, and fever prototypes > Flashcards

Pain, inflammation, and fever prototypes Flashcards

1
Q

ibuprofen drug classes

A

therapeutic: analgesic, anti-inflammatory, antipyretic
pharmacologic: NSAID, non-selective COX inhibitor

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2
Q

ibuprofen MOA

A

inhibits the conversion of arachidonic acid to cyclooxegenase (COX) which inhibits the production of prostaglandins
IMPORTANT: Prostaglandins generated by COX 1 & 2 can be BOTH protective (COX-1) and cause inflammation (COX-2)

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3
Q

ibuprofen uses

A

mild to moderate pain, fever, inflammation

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4
Q

ibuprofen nursing considerations

A

may cause GI bleeding or peptic ulcers, monitor hepatic and renal function, if allergic to Asprin avoid

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5
Q

aspirin drug classes

A

therapeutic: analgesic, anti-inflammatory, antipyretic
Pharmacologic: : NSAID, salicylate, non-selective COX inhibitor

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6
Q

aspirin MOA

A

inhibits synthesis of prostaglandins

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7
Q

aspirin uses

A

mild to moderate pain, treatment of fever, treatment of inflammation, may prevent stroke and heart attack

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8
Q

aspirin nursing considerations

A

GI irritation, don’t use with drugs that increase risk of bleeding, monitor hepatic renal function, may lead to Stevens-John syndrome

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9
Q

acetaminophen drug classes

A

therapeutic class: analgesic, antipyretic
pharmacologic class: analgesic

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10
Q

acetaminophen MOA

A

inhibits synthesis of prostaglandins in the brain

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11
Q

aceteminophen uses

A

mild to moderate pain, treatment of fever

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12
Q

acetaminophen nursing considerations

A

hepatoxic, to not use with alcoholics or hepatic insufficeincy; don’t exceed 3000mg/day

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13
Q

stevens-johnson syndrome (SJS)

A

caused by NSAIDs, serious reaction to medications that causes flu like symptoms then severe rash

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14
Q

morphine drug classes

A

therapeutic: analgesic
pharmacologic: opioid agonist

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15
Q

morphine MAO

A

works in the brain to inhibit pain sensation

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16
Q

morphine uses

A

moderate to severe pain not relieved by non-opioid medications, air hunger

17
Q

morphine nursing considerations

A

monitor for respiratory depression, sedation, urinary retention, nausea, constipation
administer stool softener
2 RN sign off

17
Q

naloxone drug classes

A

therapeutic class: reversal agent, antidote for opioids
Pharma class: CNS opioid receptor antagonist

18
Q

naloxone action

A

competes with opioids at the receptor site in the brain

19
Q

naloxone uses

A

reversal of opioid overdose

20
Q

naloxone nursing considerations

A

have drug available if giving opioids, may cause withdrawal symptoms

21
Q

methadone drug classes

A

therapeutic class: opioid analgesic
pharm class: long acting opioid agonist

22
Q

methadone MOA

A

work in brain to desensitize multiple pain receptors, blocks craving and euphoria

23
Q

methadone uses

A

uses to treat opioid disorder to facilitate medical withdrawal or chronic pain management

24
Q

methadone nursing considerations

A

may be used to facilitate opioid withdrawal after ICU stay
can cause respiratory depression
usually given as a taper overtime

25
Q

sumatriptan (Imitrex) drug classes

A

therapeutic class: vascular headache (migraine) support
pharm class: seratonin (5-HT) agonist

26
Q

sumatriptan MOA

A

causes vasoconstriction of blood vessels in the head

27
Q

sumatriptan uses

A

migraine treatment

28
Q

sumatriptan nursing considerations

A

not preventative, do not use with history of myocardial infarction, do not give with ergotamine based meds

29
Q

prednisone drug classes

A

therapeutic class: potent anti inflammatory
pharm: corticosteroid

30
Q

prednisone MOA

A

decrease inflammation and suppress immune system

31
Q

prednisone uses

A

allergic disorders, skin conditions, lupus, ulcerative colitis, Crohn’s, arthritis, psoriasis, asthma, COPD, etc

32
Q

prednisone nursing considerations

A

may cause Cushing’s syndrome, no not use with active infections, causes GI distress
Seven S’s (swollen, sepsis, sugar, skinny, sight, slowly, stress)

Pharm 1 (13 decks)

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