Pain Management Flashcards
(49 cards)
What is the definition of pain?
An unpleasant sensory and emotional experience associated with actual or potential tissue damage
Why is pain subjective?
Because it’s difficult to see, quantify, and varies between individuals
What are common causes of pain?
Injury
inflammation
cancer
unknown events
What are the types of pain mechanisms?
Neural
chemical
inflammatory mechanisms
What are the main categories of pain medication?
Opioid and non-opioid analgesics
What is tolerance?
A need to increase dosage to achieve the same effect over time
What causes opioid tolerance?
Decreased receptor sensitivity and number, discrupted receptor G protein
What is opioid-induced hyperalgesia?
Increased pain sensitivity due to chronic opioid use
How should clinicians respond to unexpected pain increase in opioid users?
Document pain reports and notify the physician
What is physical dependence?
A condition where withdrawal symptoms occur when the drug is stopped
What are the symptoms of opioid withdrawal?
Cravings\substance- seeking behavior
symptoms starting 5-10 hours after last dose
What are strong opioid agonists?
Drugs like morphine used for severe pain
What are mild-to-moderate opioid agonists?
Drugs like codeine used for moderate pain
What are mixed agonist-antagonist opioids?
Drugs that activate some receptors and block others
What are opioid antagonists?
Drugs like naloxone that block opioid receptors
How do opioids work at the spinal level?
They inhibit pain signal transmission to the brain
How do opioids work at the brain level?
They activate descending pain pathways to inhibit spinal synapses
What is the peripheral effect of opioids?
Reduce excitability of sensory neurons outside CNS
When are opioids commonly used?
Post-surgery
trauma
MI
cancer- related chronic pain
What is Patient Controlled Analgesia (PCA)?
A system allowing patients to self-administer controlled doses of pain medication
What are common opioid side effects?
Nausea
constipation
drowsiness
respiratory depression
What are serious adverse effects of opioids?
Cognitive impairments
mood changes
OH
falls
death
Why is therapy timing important with opioids?
Pain relief can improve participation if therapy is scheduled at peak drug effect
What is the onset time for oral hydromorphone?
30–90 minutes