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Anesthesiology Master > Pain Physio (EB) > Flashcards

Flashcards in Pain Physio (EB) Deck (37):
1

Why do people withhold analgesia

difficulties in recognizing pain. Lacking of knowledge in the appropriate use of analgesics. Fear of drug side effects

2

Why is it important to monitor the response to pain tx?

lots of consequences of pain

3

What 2 combinations of things is pain?

nociception and perception

4

What are the classic categorizations of pain (5)

disease Anatomy. General location Duration Intensity

5

What is physiologic/nociceptive pain? (3)

early-warning physiological protective system Touching things too hot, cold, sharp

6

What type of pain is essential for bodily integrity?

physiologic/nociceptive pain

7

What are the 2 types of pathological/clinical pain?

inflammatory Neuropathic

8

What type of pain is adaptive but still needs to be reduced?

inflammatory pain

9

What type pain must be treated?

neuropathic pain

10

What is the purpose of inflammatory pain?

assist in healing by discouraging physical contact or movement

11

What pain is not protective at all, just maladaptive?

neuropathic pain

12

What does neuropathic pain result from?

abnormal functioning of the NS

13

What fibers participate in nociception?

A-delta C A-beta

14

Pathway of nociception

transduction Transmission Modulation Projection Perception

15

What is the transduction of pain?

detection of innocuous and noxious information

16

What nerve fibers are responsible for "first pain" aka the pricking and sharp pain?

A-delta fibers

17

What type of receptors are Adelta fiber nociceptors composed of?

75% of low-threshhold 25% of high-threshold

18

What nociceptive fibers have a higher discharge rate?

A delta

19

What nociceptive fibers have a high threshold?

C fiber

20

What nociceptive fiber has a second/slow pain?

C fibers

21

What fibers have to be activated for the perception of acute pain?

both the Adelta and C nociceptors

22

What are the silent or sleeping nociceptors?

A delta and C fiber

23

What activates the silent/sleeping nociceptiors?

inflammation NOT activated by tissue damaging events

24

What stimulation are the silent/sleeping nociceptors very sensitive to?

mechanical

25

What fibers pick up a low intensity pain stimulus? What is their threshold?

A beta fibers Low threshold

26

What fibers pick up a high intensity pain stimulus? What is their threshold?

A delta and C fibers High threshold

27

What is it when A beta fibers are more easily excitable?

allodynia

28

What is it when A delta and C fibers are more easily excitable?

hyperalgesia

29

What does peripheral sensitization result in?

hyperalgesia at the site of injury (primary hyperalgesia)

30

What causes peripheral sensitization

inflammatory/sensitizing soup

31

What is responsible for pain memory?

central sensitization

32

What does central sensitization result in?

primary and secondary hyperalgesia and allodynia

33

What is wind-up

temporal summation of sensory inputs in the spinal cord

34

What drugs inhibit transduction of pain (4)

opioids Local anesthesia A2 agonists NSAIDs

35

What drugs inhibit transmission of pain (1)

local anesthesia

36

What drugs inhibit the perception of pain (5)

inhalants Sedatives Injectables Anesthesics NSAIDs

37

What drugs inhibit the projection of pain (6)

inhalant anesthetics Injectable anesthetics Local anesthetics Opioids A2 agonists ketamine