Pain/Regional Flashcards
(93 cards)
A-delta
myelinated, sharp, well localized pain, temp, touch (somatic)
C fibers
unmyelinated, poorly localized mechanical, thermal, chemical (visceral)
pain course
a-delta/c fibers send signal to doral horn (near substantia gelatinosa), travel up spinal cord to the thalamus via ipsilateral spinoreticulothalamic tract or contralateral spinothalamic tract, some travel to somatosensory cortex and some to anterior cingulated gyrus (limbic forebrain) for emotional processing
allodynia
pain due to non painful stim
hyperalgesia
increased response to pain
hyperesthesia
exaggerated pain to noxious stimuli
hypoalgesia
decreased pain to painful stimuli
dyesthesia
unpleasant, abnormal sensation (spon/evoked)
how many nodes of ranvier need to be blocked
3
CRPS 1 vs CRPS 2
no known insult, gradual onset vs known major nerve damage and distal to central spread, both don’t follow dermatomes
CRPS acute
(first stage) 1-4 weeks; red, hot, dry skin
CRPS dystrophic
(second stage) 4 weeks - 4 months; cold, clammy, white
CRPS atrophic
(third stage) after 4 months; muscle wasting, joint destruction, bone demineralization, hair loss, nail changes, thinning of skin
CRPS triad
- sensory (pain, allodynia, hyoeralgesia) 2. autonomic (edema, skin color, skin temp) 3. motor (muscle weakness, spasm, decreased ROM)
phantom limb pain
all amputees get over time, no difference traumatic or not, worse with more proximal amputation, can reactivate with spinal/epidural
phantom treatment
carbamazepine or calcitonin, TENS, narcotics (epidural/PO), peripheral/central neurolysis or nerve blocks, trigger point injections
TENS
transcutaneous electrical nerve stimulation - low intensity electrical stim releases endogenous endorphins that are inhibitory at spinal cord
spinal cord stim placement technique
needle into epidural space via paramedian using fluoro
myofascial pain syndrome
widespread aching, stiffness, erythema, fluctuations in pain intensity, 3rd/4th decade of life, can have trigger points
myofascial treatment
exercise, PT, massage, LA injections
Post herpetic neuralgia treatment
4-6 weeks post outbreak; TCAs, anticonvulsants, oral analgesics, sympathetic nerve blocks, topical LA, capsaician
ethyl alcohol
painful, immediate and profound neurolysis, hypobaric, long duration, high incidence of post neurolysis neuralgia, pure - somatic blocks, diluted - sympathetic
phenol
painless, delayed and less intense neurolysis, hyperbaric, short duration, LA properties, used for peripheral nerve blocks
methgb susceptible
benzocaine, prilocaine (build up o-toluidine), NO, G6P deficiency, methbg reductase deficiency (<4 months have this), nitrites/nitrates, anti-malaria meds, phenytoin