OpenAnesthesia Flashcards
pump flow range
1.6-3 L/min/m2
CPB mixed venous goals
SvO2 >65%
CPB glucose
aggressive (80-110 mg/dL) management ass with worse outcomes
meds to avoid with reproductive assistance, why?
droperidol and metoclopramide; both can increase prolactin levels, which can follicle maturation and corpus function
LMWH clearance
renally - prolonged in renal insufficiency, directly proportional to creatinine clearance
how to monitor enoxaparin
PTT is not usually monitored, can test anti-Xa activity (peak at 4 hours), therapeutic for tx 0.6-1.0 U/ml and ppx 0.1-0.3 U/ml
uterine atony risk factors
oxytocin, multiples, polyhydramnios, chorioamnionitis (NSAIDs irreversibly inhibit platelet function but little affect on uterine tone)
TRALI mechanism
GVHD - leukocytes/neutrophils causing flood of neutrophils and inflammatory mediators to lungs causing increased microvasc permeability
Haldane effect
Deoxygenated blood can carry increasing amounts of carbon dioxide
Bohr effect
an increase of carbon dioxide in the blood and a decrease in pH results in a reduction of the affinity of hemoglobin for oxygen
IgA deficiency considerations
blood products need to be washed before administration
cryo contains
VIII (100 IU), vWF, XIII, and fibrinogen (250 mg)
type
patient’s RBCs mixed with serum with known antigens (ABOD)
screen
(indirect) put patients serum with RBCs with known antigens
crossmatch
patient’s serum with donor cells
therapeutic hypothermia
32-34 for 24 hours
emergent therapy for stroke 2/2 air embolism
hyperbaric O2
HBO uses
arterial air embolism, CO poisoning, decompression sickness, severe anemia, hypoperfusion, gas gangrene
HBO MAC effects
decrease in MAC because HBO increases partial pressure of volatiles at higher barometric pressure and gas density increases so rotameter flowmeters will read falsely high (2% sevo at 1 atm produces same as 0.66% sevo at 3 atm)
1 mm Hg CO2 decrease - CBF?
decreases 3-4%, goal 30-35
goal CPP with increased ICP
60-70 mm Hg
prevention of contrast nephropathy
periprocedural continuous hemofiltration, oral N-acetylcysteine, bicarbonate infusion
predisposition to renal damage with contrast
Cr >1.5, GFR < 60, DM nephropathy, hypovolemia, high dose contrast media, multiple myeloma
pierre robin ass syndromes
stickler syndrome, velocardiofacial syndrome, treacher-collins