PALLIATIVE CARE Flashcards

(40 cards)

1
Q

END OF LIFE CARE
What is palliative care?

A
  • Holistic management of a pt in whom death is likely to be soon + where curative treatment no longer possible
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2
Q

END OF LIFE CARE
What care should be given to an end of life patient?

A
  • Basic care ALWAYS (warmth, comfort, shelter, freedom from pain, cleanliness, PO nutrition + hydration)
  • Artificial nutrition + hydration is considered treatment so may be withheld
  • Simplify meds, s/c if possible
  • Communication v important
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3
Q

END OF LIFE CARE
How does a patient at the end of their life present?

A
  • Sleepy, agitated, drifting in/out consciousness, confusion
  • Change in breathing pattern or dyspnoea
  • Decreased need for food + fluids
  • Loss of bladder or bowel control
  • Cold/bluish extremities, mottled skin
  • Death rattle
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4
Q

END OF LIFE CARE
What is the death rattle?
Is this dangerous?

A
  • Reduced ability to clear saliva + mucous from back of throat + hypersecretion leading to noisy airway
  • No, not painful or uncomfortable
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5
Q

END OF LIFE CARE
What issues presenting at the end of life can be managed pharmacologically?

A
  • Pain
  • Dyspnoea
  • Agitation + anxiety
  • Nausea
  • Constipation
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6
Q

END OF LIFE CARE
In terms of managing end of life care, what should be given for regular medication?

A

Syringe driver

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7
Q

END OF LIFE CARE
What are the aims of palliative care?

A

Help pt + relatives come to terms with death whilst optimising the quality of time left

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8
Q

END OF LIFE CARE
What does palliative care involve?

A

MDT approach – physical Sx relief, social, psychological, spiritual + family support

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9
Q

END OF LIFE CARE
what is the management of excessive secretions?

A

CONSERVATIVE
- avoid fluid overload = stop IV/SC fluids
- educate family that patient is not troubled

MEDICAL
- Hyoscine butylbromide 20mg SC
do not repeat within 1 hr, max dose 120mg in 24hrs

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10
Q

END OF LIFE CARE
In terms of managing end of life care, what should be given for pain + dyspnoea?

A

MORPHINE 20-30mg modified release per day with 5mg for breakthrough pain (e.g. 15mg modified release morphine BD + 5mg oral morphine for breakthrough pain)

OXYCODONE in mild/moderate renal impairment

ALFENTANIL, BUPRENORPHINE or FENTANYL in severe renal impairment

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11
Q

END OF LIFE CARE
In terms of managing end of life care, what should be given for nausea and vomiting?

A

Haloperidol 0.5-1.5mg SC
do not repeat within 4 hrs, max dose 3mg in 24hrs

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12
Q

END OF LIFE CARE
In terms of managing end of life care, what should be given for agitation, anxiety, or dyspnoea?

A

Midazolam 2.5-5mg SC
do not repeat within 1hr, max 4 doses in 24hrs

if not in terminal phase of illness
1st line = haloperidol
other options = chlorpromazine + levomepromazine

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13
Q

END OF LIFE CARE
In terms of managing end of life care, what should be given for constipation?

A

Start with stimulant laxative (senna) as opiates decrease peristalsis or stool softener if not on opiates, if not suppositories, enemas, PR evacuation

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14
Q

END OF LIFE CARE
In terms of managing end of life care, what should be given for haematuria?

A

large bleed = admission may be appropriate

non life-threatening bleeds
- encourage increased fluid intake
- exclude UTI
- etamsylate 500mg QDS
- consider referral for palliative radiotherapy

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15
Q

END OF LIFE CARE
In terms of managing end of life care, what should be given for hiccups?

A
  • chlorpromazine
  • haloperidol + gabapentin also used
  • dexamethasone if hepatic lesions
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16
Q

END OF LIFE CARE
how do you calculate the breakthrough dose for morphine?

A

1/6 of daily dose of morphine

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17
Q

END OF LIFE CARE
what should be prescribed alongside opioids?

18
Q

END OF LIFE CARE
how is metastatic bone pain managed?

A
  • strong opioids
  • bisphosphonates
  • radiotherapy
  • denosumab
19
Q

END OF LIFE CARE
what is the management of neuropathic pain?

A

1st line = amitriptyline, duloxetine, gabapentin or pregabalin
- if 1st line does not work, try one of other drugs
- tramadol may be used as rescue therapy
- topical capsaicin for localised neuropathic pain

20
Q

WHO ANALGESIC LADDER
what are the steps of the WHO pain ladder?

A

step 1 = non-opioid (e.g. paracetamol)
step 2 = weak opioid (e.g. codeine + non-opioid)
step 3 = strong opioid (e.g. morphine)

21
Q

OPIOIDS
give examples of weak opioids

A

codeine
dihydrocodeine

22
Q

OPIOIDS
give examples of strong opioids

A

morphine
diamorphine
oxycodone
hydromorphone
fentanyl
alfentanil
methadone

23
Q

OPIOIDS
what is the typical starting dose of morphine for opioid naive patients without renal impairment?

A

20-30mg daily

e.g. 10-15mg oral modified release morphine every 12 hrs

24
Q

MULTIPLE ORGAN DYSFUNCTION
what is it?

A

acute dysfunction of two or more organ systems

25
MULTIPLE ORGAN DYSFUNCTION what are the causes?
- sepsis = most common - liver failure - trauma - burns - shock - cardiac arrest - acute pancreatitis
26
MULTIPLE ORGAN DYSFUNCTION what are the clinical features?
- respiratory = hypoxia + ARDS - cardiovascular = shock + cardiac dysfunction - neurological = reduced consciousness - GI = ileus, malabsorption, jaundice - haematological = DIC - renal = AKI
27
MULTIPLE ORGAN DYSFUNCTION what scoring system can be used to assess the severity?
SOFA score
28
MULTIPLE ORGAN DYSFUNCTION what are the investigations?
- basic observations - blood tests (FBC, U&Es, CRP, clotting, LFTs) - ABG - CXR
29
MULTIPLE ORGAN DYSFUNCTION what is the management?
- sepsis 6 - treat underlying cause organ support - intubation + ventilation - inotropes, vasopressors + fluids - optimal glucose control + nutrition
30
METASTATIC DISEASE what is it?
process of cancer cells spreading from primary tumour site to other regions of the body
31
METASTATIC DISEASE what ways can cancer cells spread?
- local invasion - haematogenous - lymphatic
32
METASTATIC DISEASE what are the clinical features?
depends on where cancer has spread - bone = pain and fractures - brain = headaches, seizures or neurological deficits - lungs = cough, SOB or chest pain
33
METASTATIC DISEASE what are the investigations?
IMAGING - CT, MRI or PET scans - bone scans BIOPSY
34
METASTATIC DISEASE what is the management?
SURGERY - remove mets if accessible RADIATION - reduce the size of tumours + relieve symptoms CHEMOTHERAPY - systemic treatment to destroy cancer cells TARGETED THERAPIES - target cancer cells based on genetic makeup PALLIATIVE CARE - focus on relieving symptoms + improving quality of life
35
DEATH CONFIRMATION how is death confirmed?
- observed for signs of life for minimum 5 mins - confirmation of no palpable central pulse + no heart sounds + cardiac monitor has displayed asystole for >5 mins - absence of pupillary light reflex, corneal reflex + response to painful stimuli (supraorbital pressure)
36
DEATH CONFIRMATION how do you confirm lack of cardiac activity?
- lack of central pulse - lack of heart sounds on auscultation - cardiac monitor displaying asystole for >5 mins all of these should be looked for over a minimum of 5 minutes
37
DEATH CONFIRMATION how do you confirm lack of neurological activity?
- absence of pupillary light reflex - absence of corneal reflex - absence of response to painful stimuli (supraorbital pressure)
38
DEATH CONFIRMATION when is time of death confirmed?
can only be confirmed when lack of cardiac and neurological activity over 5 minutes has been confirmed
39
DEATH CONFIRMATION how do you confirm death if a patient has a DNACPR?
- absence of pupillary light reflex, corneal reflex + response to pain (supraorbital pressure) - no palpable central pulse + no heart sounds for 2 minutes - confirmation of no chest wall movement + no audible breath sounds for 2 minutes - no additional cardiac monitoring required in these patients
40
DEATH CONFIRMATION when can registered nurses confirm death?
all 3 must be present: - if death is expected + occurs in private residence, hospice, residential home or hospital - valid DNACPR document - no features that would prompt referral to coroner