PANCE_pharm

Question 1

(CME)
Which antibiotic is best to use against infections by anaerobic organisms?
a) erythromycin
b) penicillin
c) ceftriaxone
d) gentamicin
e) clindamycin

Answer 1

E) CLINDAMYCIN

Question 2

(CME)
Which of the following in high doses is associated with loss of red/green perception and optic neuritis?
f) gentamicin
g) ethambutol
h) doxycycline
i) streptomycin
j) vancomycin

Answer 2

G) ETHAMBUTOL

Question 3

(CME)
which of the following abx should NOT be used in pregnancy?
a) aminoglycosides & clindamycin
b) tetracyclines & metronidazole
c) azithromycin & clindamycin
d) erythromycin & meropenem
e) aminoglycosides & tetracyclines

Answer 3

E) AMINOGLYCOSIDES & TETRACYCLINES

Question 4

(CME)
which cephalosporin is best for MRSA infections?
f) cefuroxime
g) ceftaroline
h) ceftriaxone
i) cefazolin
j) cephalexin

Answer 4

G) CEFTAROLINE

(a 5th gen cephalosporin)

Question 5

(CME)
which of the following is an antipseudomonal penicillin?
a) nafcillin
b) oxacillin
c) dicloxacillin
d) piperacillin
e) I-don’t-know-a-cillin

Answer 5

D) PIPERACILLIN

Question 6

(RR)
what is the MOA of ondansetron?

Answer 6

serotonin receptor antagonist

Question 7

(RR)
what sulfa-containing antibiotic should be avoided in a pt with G6PD deficiency?

Answer 7

trimethoprim-sulfamethoxazole (TMP-SMX)

“since it contains a sulfa moiety which could precipitate hemolysis”

Question 8

(CME)
“What is the antidote for an overdose of benzodiazepines?”

Answer 8

FLUMAZENIL

Question 9

(CME)
“Which of the following causes mydriasis?
a) diphenhydramine
b) clonidine
c) thorazine
d) fentanyl”

Answer 9

A) DIPHENHYDRAMINE

Question 10

(RR)
What abx are used as a substitute for pt’s with a penicillin allergy?

Answer 10

macrolides

Question 11

REMEMBER:

CT with contrast is contraindicated in patients with

Answer 11

elevated Cr or signs of kidney failure

Question 12

(RR)
most notable abx that cause ototoxicity

Answer 12

aminoglycosides

Question 13

(RR)
name some drugs which cause permanent sensorineural hearing loss

Answer 13

aminoglycosides
erythromycin
tetracycline (esp in those w/ renal impairment)
chemo agents like cisplatin and 5-FU
sildenafil

Question 14

(RR)
name some drugs which cause reversible sensorineural hearing loss (reversible once agent is d/c’d)

Answer 14

ASA
acetaminophen
NSAIDs
loop diruetic
quinin
chlorquine

Question 15

(RR)
“What is a serious complication that develops in children who are given aspirin with a viral syndrome?”

Answer 15

“Reye’s syndrome”