Flashcards in Pancreatic Cancer Deck (12):
Functions of pancreas
Exocrine- digestive enzymes
Endocrine- islet cells involved with blood sugar regulation
RF pancreatic cancer
- chronic pancreatitis
- family history of global malignancy
- painless jaundice
- unintentional weight loss
- recent onset of atypical DM
- palpable mass (late stage)
- ascites (late stage)
- courvoisier's sign
What is courvoisier's sign?
non-tender palpable gallbladder with jaundice
LFT- increased and bilirubin increase if bile can't get out
CA 19-9 (pancreatic cancer tumor marker)
- Start with ultrasound to look at biliary system
- then do CT
- MRI is best imaging modality
- Endoscopic ultrasound lets us look at pancreas, biopsy the tumor and look at the lymph nodes around
- only curative approach is surgery
- stage 1 to 2b is most likely to be cured by radical resection
- do a whipple if tumor in head of pancreas
- distal pancreatectomy is tumor in body or tail
What is a whipple?
1. resection of head of pancreas
2. excise the duodenum and bile duct
3. reconstruction with intestine
What is a majority of primary pancreatic cancer?
Where do most cancers arise?
When most pancreatic cancers discovered where are they found?
metastasized to peripancreatic lymph nodes