Parathyroid Hormone Disorders

Question 1

What is the PT gland?

Answer 1

These are two sets of glands situated in the back of the thyroid gland, that produce, store and secrete PTH

Question 2

What type of hormone is PTH?

Answer 2

Protein hormone so unbound in circulation

Question 3

In what is PTH brojen down into?

Answer 3

N terminak fragment and C terminal fragment

Question 4

What fragment of PTH is thiught tobe the most active although both are?

Answer 4

N terminal

Question 5

What us tye major regulator of PTH release?

Answer 5

Free ionized calcium

Question 6

What other substances slightly regulate PTH aside Ca?

Answer 6

Mg
Biogenic amines
Vitamin D

Question 7

What is the relationship between calcium keevks and PTH release?

Answer 7

Low serum ionized calcium stimulates secretion of PTH which ultimately works to increase serum calcium through different mechanisms

Question 8

What are the functions of PTH?

Answer 8

Mineral homeostasis in kidney and bone

Increase plasma Ca and reduce plasma PO4

Question 9

What does the body require calcium for?

Answer 9

Muscle contraction (heart and muscle), hemostasis, cellular responsiveness and bone growth.