Parkinsons Flashcards
1
Q
What is the pathophysiology behind Parkinson’s
A
Decreased dopamine production and decreased dopamine recptors
2
Q
Cardinal Signs of Parkinson’s
A
Resting tremor, bradykinesia, and rigidity
3
Q
How to diagnose Parkinson’s; include criteria, imagining, and genetic testing options
A
2/3 Parkinson’s symptoms and improvement with levodopa
PET scan; reduced uptake of dopamine
Genetic testing; not routinely done but can be done in <40 yr olds
4
Q
Parkinson’s pharmacological treatment options
A
Carbidopa/levodopa
Selegiline or Relagiline - MAOBs
Tolcapone- COMPT
Caffeine
