Part 1

Question 1

He observe the plague in Athens that individuals who had previously contracted the disease recovered
(“immune” status)

Answer 1

Thucydides

Question 2

deliberately expose the individual to the material from smallpox lesion

Answer 2

variolation

Question 3

He discovered a relationship between exposure to cowpox and immunity to smallpox

Answer 3

Edward Jenner (1700s)

Question 4

Spearheaded the vaccination

Answer 4

Edward Jenner (1700s)

Question 5

He observed that foreign objects introduced into to your starfish larvae becomes surrounded by motile
cells that would attempt to destroy the invaders. He was the one who coined the term phagocytosis

Answer 5

Elie Metchniko

Question 6

the Father of Immunology; discovered the first attenuated vaccine

Answer 6

Louis Pasteur

Question 7

was the T figure in the development of both microbiology and immunology

Answer 7

Louis Pasteur

Question 8

Discovered Complement

Answer 8

Jules Bordet

Question 9

Discovered Precipitins

Answer 9

Robert Kaus

Question 10

First immunology related Nobel Prize for his work on serum therapy

Answer 10

Emil Alolf von Behring

Question 11

discovered that Immune response involved both cellular and humoral elements

Answer 11

Almoth Wright

Question 12

won the Nobel prize for the discovery of the genetic principles underlying the generation antibodies
with di erent specificities

Answer 12

Susumu Tonegawa

Question 13

Therapeutic vaccination First report of live “attenuated” vaccine for rabies

Answer 13

Pasteur

Question 14

Demonstration of cutaneous Delayed-type) hypersensitivity

Answer 14

koch

Question 15

Antibody formation theory

Answer 15

Ehrlich

Question 16

Development of polio vaccine

Answer 16

Salk, Sabin

Question 17

Graft-versus-host reaction

Answer 17

reed

Question 18

Development of human papillomavirus vaccine

Answer 18

Frazer

Question 19

Deals with the substances usually proteins that are present in the body fluids

Answer 19

Humoral Immunity

Question 20

Deals with the substances usually proteins that are present in the body fluids

Answer 20

Humoral Immunity

Question 21

The cellular aspect of immunity deals with the cells

Answer 21

Cellular immunity

Question 22

this immunity consists of
Anatomic barriers
Resident flora
Humoral factors
Cells

Answer 22

INNATE IMMUNITY

Question 23

has memory and specificity

Answer 23

adapative

Question 24

Considered non adaptive or nonspecific

Answer 24

Innate Immunity

Question 25

Response is the same for all pathogens or foreign substances after exposure

Answer 25

Innate Immunity

Question 26

Defense System that is designed the keep the microorganism from entering the body: They are structural barriers that prevent most infectious agent from entering the body

Answer 26

External Defense System

Question 27

This defense mechanism has no specificity and they limit the entry of all pathogens in respective of which one is trying to reach the integrity of the body

Answer 27

External Defense System

Question 28

They are non-pathogenic bacteria of the intestines, vagina and nasopharynx. They prevent the colonization of new microorganisms because the new microorganism cannot establish themselves in the region where other microbes are already thriving

Answer 28

resident flora

Question 29

defense mechanism that is designed to recognize the molecules that are unique to infection organism

Answer 29

Internal defense system

Question 30

kind of humoral factor that is Present in tears, sebaceous, and sweat gland secretions that will cleave the cell wall of bacteria

Answer 30

lysozyme

Question 31

present in tears, sebaceous and sweat glands secretions and it will bind iron which is an essential growth molecule for bacteria or microbes restricting the amount of iron that is essential for the growth of bacteria

Answer 31

lactoferrin

Question 32

Present in stomach which will digest bacterial surface protein and that would bind to cells that are present in the intestinal laminae

Answer 32

pepsin

Question 33

Provide host defense because many organisms cannot survive the acidic environment of the stomach and they are destroyed before entering the small intestine.

Answer 33

stomach acidity

Question 34

Made up of family of proteins (around 30 proteins) whose coordinated actions will lead to the destruction of microorganisms particularly the extracellular bacteria

Answer 34

complement

Question 35

Cells that are present in the bone marrow (bone marrow derived cells). They are recruited when the initial barriers have been breach and antigens sub succeeded in entering the body

Answer 35

Cellular defense

Question 36

Cells that will engulf and destroy foreign substances and microorganism

Answer 36

phagocytes

Question 37

Eliminate virally infected cells

Answer 37

neutrophils

Question 38

Eliminates helminths

Answer 38

eosinophils

Question 39

release substances into the local micro-environment that can facilitate recruitment of immune cells to the site of infection

Answer 39

mast cells and basophils